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Grp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH

The Journal of biological chemistry, 2024-06, Vol.300 (6), p.107346, Article 107346

2024

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Cell biology of prion strains in vivo and in vitro

Cell and tissue research, 2023-04, Vol.392 (1), p.269-283

2023

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Full-length prion protein incorporated into prion aggregates is a marker for prion strain-specific destabilization of aggregate structure following cellular uptake

Journal of biochemistry (Tokyo), 2023-07, Vol.174 (2), p.165-181

2023

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The Size and Stability of Infectious Prion Aggregates Fluctuate Dynamically during Cellular Uptake and Disaggregation

Biochemistry (Easton), 2021-02, Vol.60 (5), p.398-411

2021

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Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

PloS one, 2022-05, Vol.17 (5), p.e0267720-e0267720

2022

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Cell Biology Approaches to Studying Prion Diseases

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1658, p.83

Priola, Suzette A

2017

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The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

PloS one, 2024-02, Vol.19 (2), p.e0298095-e0298095

2024

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Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006491-e1006491

2017

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α-Synuclein strain propagation is independent of cellular prion protein expression in a transgenic synucleinopathy mouse model

PLoS pathogens, 2024-09, Vol.20 (9), p.e1012517

2024

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Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein

PLoS pathogens, 2024-07, Vol.20 (7), p.e1012350

2024

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Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

PloS one, 2019-07, Vol.14 (7), p.e0219457-e0219457

2019

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Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease

PLoS pathogens, 2024-04, Vol.20 (4), p.e1012087-e1012087

2024

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Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein

Nature methods, 2007-08, Vol.4 (8), p.645-650

2007

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Anchorless Prion Protein Results in Infectious Amyloid Disease Without Clinical Scrapie

Science (American Association for the Advancement of Science), 2005-06, Vol.308 (5727), p.1435-1439

2005

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Recombinant prion protein refolded with lipid and RNA has the biochemical hallmarks of a prion but lacks in vivo infectivity

PloS one, 2013-07, Vol.8 (7), p.e71081-e71081

2013

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Processing of high-titer prions for mass spectrometry inactivates prion infectivity

Biochimica et biophysica acta. Proteins and proteomics, 2018-11, Vol.1866 (11), p.1174-1180

2018

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Cellular prion protein is present in mitochondria of healthy mice

Scientific reports, 2017-02, Vol.7 (1), p.41556-41556, Article 41556

2017

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Mitochondrial Respiration Is Impaired during Late-Stage Hamster Prion Infection

Journal of virology, 2017-09, Vol.91 (18)

2017

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A Specific Population of Abnormal Prion Protein Aggregates Is Preferentially Taken Up by Cells and Disaggregated in a Strain-Dependent Manner

Journal of Virology, 2013-11, Vol.87 (21), p.11552-11561

2013

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Efficacy of Wex-cide 128 disinfectant against multiple prion strains

PloS one, 2023-08, Vol.18 (8), p.e0290325-e0290325

2023

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Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

Nature methods, 2008-03, Vol.5 (3), p.211-212

2008

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The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

PLoS pathogens, 2016-02, Vol.12 (2), p.e1005416-e1005416

2016

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PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection

Journal of virology, 2017-01, Vol.91 (2)

2017

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Prion strains depend on different endocytic routes for productive infection

Scientific reports, 2017-07, Vol.7 (1), p.6923-15, Article 6923

2017

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Susceptibility of Common Fibroblast Cell Lines to Transmissible Spongiform Encephalopathy Agents

The Journal of infectious diseases, 2004-02, Vol.189 (3), p.431-439

2004

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Grp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH

Cell biology of prion strains in vivo and in vitro

Full-length prion protein incorporated into prion aggregates is a marker for prion strain-specific destabilization of aggregate structure following cellular uptake

The Size and Stability of Infectious Prion Aggregates Fluctuate Dynamically during Cellular Uptake and Disaggregation

Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

Cell Biology Approaches to Studying Prion Diseases

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

α-Synuclein strain propagation is independent of cellular prion protein expression in a transgenic synucleinopathy mouse model

Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein

Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease

Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein

Anchorless Prion Protein Results in Infectious Amyloid Disease Without Clinical Scrapie

Recombinant prion protein refolded with lipid and RNA has the biochemical hallmarks of a prion but lacks in vivo infectivity

Processing of high-titer prions for mass spectrometry inactivates prion infectivity

Cellular prion protein is present in mitochondria of healthy mice

Mitochondrial Respiration Is Impaired during Late-Stage Hamster Prion Infection

A Specific Population of Abnormal Prion Protein Aggregates Is Preferentially Taken Up by Cells and Disaggregated in a Strain-Dependent Manner

Efficacy of Wex-cide 128 disinfectant against multiple prion strains

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection

Prion strains depend on different endocytic routes for productive infection

Susceptibility of Common Fibroblast Cell Lines to Transmissible Spongiform Encephalopathy Agents

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