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Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

Biochemical pharmacology, 2017-03, Vol.127, p.13-27

2017

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Structure-Antifungal Activity Relationships of Polyene Antibiotics of the Amphotericin B Group

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3815-3822

2013

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Bacterial eukaryotic type serine-threonine protein kinases: from structural biology to targeted anti-infective drug design

Current topics in medicinal chemistry, 2011-06, Vol.11 (11), p.1352-1369

2011

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Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

European journal of medicinal chemistry, 2016-04, Vol.112, p.114-129

2016

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Two approaches to the use of benzo[c][1,2]oxaboroles as active fragments for synthetic transformation of clarithromycin

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.452-456

2017

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Thienoquinolines as Novel Disruptors of the PKCε/RACK2 Protein–Protein Interaction

Journal of medicinal chemistry, 2014-04, Vol.57 (8), p.3235-3246

2014

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Synthesis and Characterization of 4,11-Diaminoanthra[2,3‑b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD+/NADH Ratio and SIRT1

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9522-9534

2015

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Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain

Bioorganic & medicinal chemistry, 2013-06, Vol.21 (11), p.2918-2924

2013

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Glycopeptide antibiotic analogs efficient against vancomycin-resistant bacteria: a patent evaluation (WO2013022763)

Expert opinion on therapeutic patents, 2013-12, Vol.23 (12), p.1625-1634

2013

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Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties

Drug design, development and therapy, 2018-01, Vol.12, p.2875-2885

2018

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Deboronation of New Clarithromycin-Benzo[c][1,2]oxaborole Conjugates

Anti-Infective Agents, 2019, Vol.17 (2), p.99-104

2019

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Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones

European journal of medicinal chemistry, 2014-10, Vol.86, p.797-805

2014

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Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1829-1835

2003

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Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates

Journal of photochemistry and photobiology. B, Biology, 2016-09, Vol.162, p.570-576

2016

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Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A

Journal of antibiotics, 2013-09, Vol.66 (9), p.523-530

2013

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Macrolactones built from the bis-3,4(indol-1-yl)maleimide scaffold

Tetrahedron, 2014-01, Vol.70 (3), p.625-630

2014

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Study on retroaldol degradation products of antibiotic oligomycin A

Journal of antibiotics, 2014-02, Vol.67 (2), p.153-158

2014

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Synthesis and properties of a novel brominated oligomycin A derivative

Journal of antibiotics, 2012-04, Vol.65 (4), p.223-225

2012

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Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics

Journal of antimicrobial chemotherapy, 2011-06, Vol.66 (6), p.1287-1294

2011

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A novel acyclic oligomycin A derivative formed via retro-aldol rearrangement of oligomycin A

Journal of antibiotics, 2012-08, Vol.65 (8), p.405-411

2012

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The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics

European journal of medicinal chemistry, 2011-01, Vol.46 (1), p.423-428

2011

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1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

Chemico-biological interactions, 2010-08, Vol.186 (3), p.255-266

2010

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Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (24), p.7387-7393

2011

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Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling

Molecular carcinogenesis, 2012-11, Vol.51 (11), p.881-894

2012

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N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

Biochemical pharmacology, 2008-02, Vol.75 (3), p.713-724

2008

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Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

Structure-Antifungal Activity Relationships of Polyene Antibiotics of the Amphotericin B Group

Bacterial eukaryotic type serine-threonine protein kinases: from structural biology to targeted anti-infective drug design

Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

Two approaches to the use of benzo[c][1,2]oxaboroles as active fragments for synthetic transformation of clarithromycin

Thienoquinolines as Novel Disruptors of the PKCε/RACK2 Protein–Protein Interaction

Synthesis and Characterization of 4,11-Diaminoanthra[2,3‑b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD+/NADH Ratio and SIRT1

Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain

Glycopeptide antibiotic analogs efficient against vancomycin-resistant bacteria: a patent evaluation (WO2013022763)

Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties

Deboronation of New Clarithromycin-Benzo[c][1,2]oxaborole Conjugates

Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones

Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches

Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates

Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A

Macrolactones built from the bis-3,4(indol-1-yl)maleimide scaffold

Study on retroaldol degradation products of antibiotic oligomycin A

Synthesis and properties of a novel brominated oligomycin A derivative

Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics

A novel acyclic oligomycin A derivative formed via retro-aldol rearrangement of oligomycin A

The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics

1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics

Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

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