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Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

PloS one, 2017-12, Vol.12 (12), p.e0184876

2017

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An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

The Journal of pharmacology and experimental therapeutics, 2012-04, Vol.341 (1), p.225

2012

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Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats

The Journal of pharmacology and experimental therapeutics, 2013-02, Vol.344 (2), p.397

2013

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Behavioral characterization of mice lacking GIRK/Kir3 channel subunits

Genes, brain and behavior, 2008-07, Vol.7 (5), p.523-531

2008

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Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder

Neuropharmacology, 2021-09, Vol.195, p.108653-108653, Article 108653

2021

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Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Molecular pharmaceutics, 2019-06, Vol.16 (6), p.2364-2375

2019

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Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats

Vaccine, 2012-06, Vol.30 (31), p.4617-4624

2012

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The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence

Vaccine, 2015-11, Vol.33 (46), p.6332-6339

2015

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Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse

Journal of immunological methods, 2014-03, Vol.405, p.74-86

2014

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Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

Biochemical pharmacology, 2012-02, Vol.83 (4), p.543-550

2012

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Oxycodone self-administration in male and female rats

Psychopharmacology, 2017-03, Vol.234 (6), p.977-987

2017

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Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats

Biochemical pharmacology, 2011-05, Vol.81 (9), p.1164-1170

2011

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A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats

The Journal of pharmacology and experimental therapeutics, 2019-02, Vol.368 (2), p.282

2019

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Preclinical Efficacy and Characterization of Candidate Vaccines for Treatment of Opioid Use Disorders Using Clinically Viable Carrier Proteins

Molecular pharmaceutics, 2018-11, Vol.15 (11), p.4947-4962

2018

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Development of vaccines for treatment of opioid abuse using carrier proteins suitable for pharmaceutical manufacturing

The Journal of immunology (1950), 2018, Vol.200 (1_Supplement), p.181-181.28

2018

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Alum adjuvant is more effective than MF59 in promoting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of candidate vaccines against opioid abuse in adult and old mice

The Journal of immunology (1950), 2018, Vol.200 (1_Supplement), p.181-181.20

2018

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Immunogenicity of individual vaccine components in a bivalent nicotine vaccine differ according to vaccine formulation and administration conditions

PloS one, 2013-12, Vol.8 (12), p.e82557-e82557

2013

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Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum

Vaccine, 2013-12, Vol.31 (52), p.6185-6193

2013

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Quantification of Housekeeping Transcript Levels During the Development of Bovine Preimplantation Embryos

Biology of reproduction, 2002-11, Vol.67 (5), p.1465-1472

2002

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Vasoconstriction Caused by Cocaine is Enhanced by Sodium Salicylate: Is Inducible Nitric Oxide Synthase mRNA Related?

Neuropsychopharmacology (New York, N.Y.), 2004-07, Vol.29 (7), p.1294-1300

2004

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Quantification of Housekeeping Transcript Levels During the Development of Bovine Preimplantation Embryos

Biology of reproduction, 2002-10, Vol.67 (5), p.1465-1472

2002

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Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system

Neuropsychopharmacology (New York, N.Y.), 2020-10, Vol.45 (11), p.1781-1792

2020

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Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity

The Journal of pharmacology and experimental therapeutics, 2022-05, Vol.381 (2), p.129

2022

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GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner

The Journal of neuroscience, 2015-05, Vol.35 (18), p.7131-7142

2015

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Effect of currently approved carriers and adjuvants on the pre-clinical efficacy of a conjugate vaccine against oxycodone in mice and rats

PloS one, 2014-05, Vol.9 (5), p.e96547

2014

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Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats

Behavioral characterization of mice lacking GIRK/Kir3 channel subunits

Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats

The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence

Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse

Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

Oxycodone self-administration in male and female rats

Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats

A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats

Preclinical Efficacy and Characterization of Candidate Vaccines for Treatment of Opioid Use Disorders Using Clinically Viable Carrier Proteins

Development of vaccines for treatment of opioid abuse using carrier proteins suitable for pharmaceutical manufacturing

Alum adjuvant is more effective than MF59 in promoting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of candidate vaccines against opioid abuse in adult and old mice

Immunogenicity of individual vaccine components in a bivalent nicotine vaccine differ according to vaccine formulation and administration conditions

Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum

Quantification of Housekeeping Transcript Levels During the Development of Bovine Preimplantation Embryos

Vasoconstriction Caused by Cocaine is Enhanced by Sodium Salicylate: Is Inducible Nitric Oxide Synthase mRNA Related?

Quantification of Housekeeping Transcript Levels During the Development of Bovine Preimplantation Embryos

Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system

Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity

GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner

Effect of currently approved carriers and adjuvants on the pre-clinical efficacy of a conjugate vaccine against oxycodone in mice and rats

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