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Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Immunity (Cambridge, Mass.), 2014-01, Vol.40 (1), p.128-139

2014

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Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond

Pharmacology & therapeutics (Oxford), 2009-01, Vol.121 (1), p.29-40

2009

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Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages

Frontiers in immunology, 2021-07, Vol.12, p.691134-691134

2021

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Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host

Current opinion in pharmacology, 2013-12, Vol.13 (6), p.869-874

2013

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Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity

Frontiers in immunology, 2020-02, Vol.11, p.122-122

2020

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DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Nature communications, 2015-04, Vol.6 (1), p.6910-6910, Article 6910

2015

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Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

Pharmacology & therapeutics (Oxford), 2016-08, Vol.164, p.144-151

2016

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Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway

Cancer research (Chicago, Ill.), 2019-08, Vol.79 (15), p.3837-3850

2019

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Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer

Biochemical journal, 2015-07, Vol.469 (1), p.17-23

2015

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GPR109A Is a G-protein―Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.2826-2832

2009

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Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

The Journal of biological chemistry, 2010-09, Vol.285 (36), p.27601-27608

2010

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Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3

Biochemical journal, 2009-01, Vol.417 (1), p.379-389

2009

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The Niacin/Butyrate Receptor GPR109A Suppresses Mammary Tumorigenesis by Inhibiting Cell Survival

Cancer research (Chicago, Ill.), 2014-02, Vol.74 (4), p.1166-1178

2014

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Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

Endocrinology (Philadelphia), 2011-03, Vol.152 (3), p.1119-1129

2011

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High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

The FASEB journal, 2009-01, Vol.23 (1), p.271-278

2009

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SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer

The Journal of biological chemistry, 2011-09, Vol.286 (36), p.31830-31838

2011

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Canonical Wnt Signaling in CD11c + APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon

The Journal of immunology (1950), 2018-05, Vol.200 (9), p.3259-3268

2018

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The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

Biochemical journal, 2013-02, Vol.450 (1), p.169-178

2013

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SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter

Life sciences (1973), 2006-04, Vol.78 (21), p.2419-2425

2006

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Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

Biochemical journal, 2008-09, Vol.414 (3), p.343-355

2008

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Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

Biochemical journal, 2005-12, Vol.392 (Pt 3), p.655-664

2005

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Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis

Investigative ophthalmology & visual science, 2016-04, Vol.57 (4), p.1612-1619

2016

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SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases

Cancer research (Chicago, Ill.), 2006-12, Vol.66 (24), p.11560-11564

2006

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Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

Molecular and Cellular Biology, 2013-10, Vol.33 (19), p.3920-3935

2013

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Mouse Models of Colitis-Associated Colon Cancer

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2224, p.133

2021

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Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond

Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages

Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host

Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway

Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer

GPR109A Is a G-protein―Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3

The Niacin/Butyrate Receptor GPR109A Suppresses Mammary Tumorigenesis by Inhibiting Cell Survival

Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer

Canonical Wnt Signaling in CD11c + APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon

The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases

Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

Mouse Models of Colitis-Associated Colon Cancer

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