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What is new in LC-MS proteomics: Techniques and applications in IVIVE and precision medicine

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100563, Article 100563

Prasad, Bhagwat

2024

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S8.4 - Integrated quantitative proteomics and metabolomics approach for discovery and validation of UGT2B17 biomarker to predict drug metabolism

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S14-S14

Prasad, Bhagwat

2020

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Quality-by-design (QBD) approach to address rigor and reproducibility in dmet quantitative proteomics

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S70-S70

Prasad, Bhagwat

2019

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Bacterial chromate reductase, a potential enzyme for bioremediation of hexavalent chromium: A review

Journal of environmental management, 2014-12, Vol.146, p.383-399

2014

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Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.802-808

2019

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Quantitative analysis of hepatic transporters and DMEs during growth and development

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S12-S12

Prasad, Bhagwat

2017

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Utility of Quantitative Proteomics for Enhancing the Predictive Ability of Physiologically Based Pharmacokinetic Models Across Disease States

Journal of clinical pharmacology, 2020-10, Vol.60 (S1 Suppl 1), p.S17-S35

2020

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Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics

The AAPS journal, 2014-07, Vol.16 (4), p.634-648

2014

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Meta-Analysis of Food Effect on Oral Absorption of Efflux Transporter Substrate Drugs: Does Delayed Gastric Emptying Influence Drug Transport Kinetics?

Pharmaceutics, 2021-07, Vol.13 (7), p.1035

2021

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Can LS180 cells predict metabolism and drug-drug interaction potential of UGT2B17 substrates?

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100917, Article 100917

2024

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Harnessing Solute Carrier Transporters for Precision Oncology

Molecules (Basel, Switzerland), 2017-03, Vol.22 (4), p.539

2017

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Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.131-141

2019

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Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

Pharmaceutical research, 2020-12, Vol.37 (12), p.250, Article 250

2020

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Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics

Drug metabolism and disposition, 2016-12, Vol.44 (12), p.1920-1924

2016

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Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.216-223

2017

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Protein Abundance of Clinically Relevant Multidrug Transporters along the Entire Length of the Human Intestine

Molecular pharmaceutics, 2014-10, Vol.11 (10), p.3547-3555

2014

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Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins

Drug metabolism and disposition, 2015-12, Vol.43 (12), p.1872-1881

2015

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Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Drug metabolism and disposition, 2015-03, Vol.43 (3), p.367-374

2015

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Novel metabolomics approach to identify biomarkers of organic anion renal transporters

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100805, Article 100805

2024

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Global Proteomics Analysis of Lysophosphatidic Acid Signaling in PC-3 Human Prostate Cancer Cells: Role of CCN1

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2067

2024

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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.525-543

2019

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Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex

Drug metabolism and disposition, 2014-01, Vol.42 (1), p.78-88

2014

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Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

Clinical pharmacology and therapeutics, 2019-07, Vol.106 (1), p.228-237

2019

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Interindividual Variability in the Hepatic Expression of the Human Breast Cancer Resistance Protein (BCRP/ABCG2): Effect of Age, Sex, and Genotype

Journal of pharmaceutical sciences, 2013-03, Vol.102 (3), p.787-793

2013

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Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human

Molecular pharmaceutics, 2020-11, Vol.17 (11), p.4114-4124

2020

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What is new in LC-MS proteomics: Techniques and applications in IVIVE and precision medicine

S8.4 - Integrated quantitative proteomics and metabolomics approach for discovery and validation of UGT2B17 biomarker to predict drug metabolism

Quality-by-design (QBD) approach to address rigor and reproducibility in dmet quantitative proteomics

Bacterial chromate reductase, a potential enzyme for bioremediation of hexavalent chromium: A review

Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics

Quantitative analysis of hepatic transporters and DMEs during growth and development

Utility of Quantitative Proteomics for Enhancing the Predictive Ability of Physiologically Based Pharmacokinetic Models Across Disease States

Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics

Meta-Analysis of Food Effect on Oral Absorption of Efflux Transporter Substrate Drugs: Does Delayed Gastric Emptying Influence Drug Transport Kinetics?

Can LS180 cells predict metabolism and drug-drug interaction potential of UGT2B17 substrates?

Harnessing Solute Carrier Transporters for Precision Oncology

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Protein Abundance of Clinically Relevant Multidrug Transporters along the Entire Length of the Human Intestine

Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins

Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Novel metabolomics approach to identify biomarkers of organic anion renal transporters

Global Proteomics Analysis of Lysophosphatidic Acid Signaling in PC-3 Human Prostate Cancer Cells: Role of CCN1

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex

Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

Interindividual Variability in the Hepatic Expression of the Human Breast Cancer Resistance Protein (BCRP/ABCG2): Effect of Age, Sex, and Genotype

Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human

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