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Applying the Retro-Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood-Brain Barrier

Angewandte Chemie International Edition, 2015-03, Vol.54 (13), p.3967-3972

International ed. in English, 2015

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Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

Scientific reports, 2022-09, Vol.12 (1), p.15810-15810, Article 15810

2022

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Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6016

2023

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The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

Schizophrenia research, 2016-11, Vol.177 (1-3), p.37-43

2016

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N-Methyl Phenylalanine-Rich Peptides as Highly Versatile Blood−Brain Barrier Shuttles

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2354-2363

2010

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The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia

European neuropsychopharmacology, 2017-02, Vol.27 (2), p.180-191

2017

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Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia

Journal of psychiatric research, 2014-11, Vol.58, p.189-196

2014

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The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

Biomedicines, 2022-08, Vol.10 (9), p.2117

2022

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Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor

Biomaterials, 2012-10, Vol.33 (29), p.7194-7205

2012

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Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

Cell chemical biology, 2018-08, Vol.25 (8), p.1031-1037.e4

2018

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The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-16

2021

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Applying the Retro-Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood-Brain Barrier

Angewandte Chemie, 2015-03, Vol.127 (13), p.4039-4044

2015

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A MALDI-TOF-based Method for Studying the Transport of BBB Shuttles—Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models

Scientific reports, 2019-03, Vol.9 (1), p.4875, Article 4875

2019

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Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7516-7524

2008

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Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors

Bioorganic chemistry, 2020-01, Vol.94, p.103365, Article 103365

2020

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Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation

Biochimica et biophysica acta. Biomembranes, 2019-07, Vol.1861 (7), p.1302-1316

2019

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HAI Peptide and Backbone Analogs—Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles

Scientific reports, 2018-12, Vol.8 (1), p.17932-11, Article 17932

2018

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Dual system for the central nervous system targeting and blood-brain barrier transport of a selective prolyl oligopeptidase inhibitor

Biopolymers, 2013-11, Vol.100 (6), p.662-674

2013

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Development of Innovative Antiatherosclerotic Peptides through the Combination of Molecular Modeling and a Dual (Biochemical‐Cellular) Screening System

Advanced therapeutics, 2020-08, Vol.3 (8), p.n/a

2020

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Peptide POP inhibitors for the treatment of the cognitive symptoms of schizophrenia

Future medicinal chemistry, 2013-09, Vol.5 (13), p.1509-1523

2013

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Rational design of a selective covalent modifier of G protein βγ subunits

Molecular pharmacology, 2011-01, Vol.79 (1), p.24-33

2011

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A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles

Advances in experimental medicine and biology, 2009, Vol.611, p.227-228

2009

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Does the Solid-Phase Synthesis of a Tetrapeptide Represent a Challenge at the Onset of the XXI Century? The Case of Cyclo [(3R)-3-hydroxydecanoyl-l-seryl-(3R)-3-hydroxydecanoyl-l-seryl]

International journal of peptide research and therapeutics, 2007-06, Vol.13 (1-2), p.313-327

2007

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RockGIS: a GIS-based model for the analysis of fragmentation in rockfalls

Landslides, 2017-10, Vol.14 (5), p.1565-1578

2017

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Simulation of Full-Scale Rockfall Tests with a Fragmentation Model

Geosciences (Basel), 2020-05, Vol.10 (5), p.168

2020

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Applying the Retro-Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood-Brain Barrier

Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia

The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

N-Methyl Phenylalanine-Rich Peptides as Highly Versatile Blood−Brain Barrier Shuttles

The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia

Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia

The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor

Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects

Applying the Retro-Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood-Brain Barrier

A MALDI-TOF-based Method for Studying the Transport of BBB Shuttles—Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models

Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors

Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation

HAI Peptide and Backbone Analogs—Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles

Dual system for the central nervous system targeting and blood-brain barrier transport of a selective prolyl oligopeptidase inhibitor

Development of Innovative Antiatherosclerotic Peptides through the Combination of Molecular Modeling and a Dual (Biochemical‐Cellular) Screening System

Peptide POP inhibitors for the treatment of the cognitive symptoms of schizophrenia

Rational design of a selective covalent modifier of G protein βγ subunits

A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles

Does the Solid-Phase Synthesis of a Tetrapeptide Represent a Challenge at the Onset of the XXI Century? The Case of Cyclo [(3R)-3-hydroxydecanoyl-l-seryl-(3R)-3-hydroxydecanoyl-l-seryl]

RockGIS: a GIS-based model for the analysis of fragmentation in rockfalls

Simulation of Full-Scale Rockfall Tests with a Fragmentation Model

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