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Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice

European journal of medicinal chemistry, 2023-02, Vol.247, p.115050-115050, Article 115050

2023

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Mannich Ketones as Possible Antimycobacterial Agents

Archiv der Pharmazie (Weinheim), 2017-09, Vol.350 (9), p.n/a

2017

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Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

Medicinal chemistry research, 2019-09, Vol.28 (9), p.1448-1460

2019

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Antifungal activity of fused Mannich ketones triggers an oxidative stress response and is Cap1-dependent in Candida albicans

PloS one, 2013-04, Vol.8 (4), p.e62142

2013

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Antifungal unsaturated cyclic Mannich ketones and amino alcohols: Study of mechanism of action

European journal of medicinal chemistry, 2009-05, Vol.44 (5), p.1823-1829

2009

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A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy

Molecules (Basel, Switzerland), 2019-11, Vol.24 (22), p.4197

2019

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The impact of 17β-estradiol on the estrogen-deficient female brain: from mechanisms to therapy with hot flushes as target symptoms

Frontiers in endocrinology (Lausanne), 2024-01, Vol.14, p.1310432-1310432

2024

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Proteomics-Based Identification of Retinal Protein Networks Impacted by Elevated Intraocular Pressure in the Hypertonic Saline Injection Model of Experimental Glaucoma

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12592

2023

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Application of Screening Experimental Designs to Assess Chromatographic Isotope Effect upon Isotope-Coded Derivatization for Quantitative Liquid Chromatography–Mass Spectrometry

Analytical chemistry (Washington), 2014-07, Vol.86 (14), p.7033-7040

2014

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Comparative Proteomics Analysis Reveals Unique Early Signaling Response of Saccharomyces cerevisiae to Oxidants with Different Mechanism of Action

International journal of molecular sciences, 2020-12, Vol.22 (1), p.167

2020

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The Antagonist pGlu-βGlu-Pro-NH2 Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor

Molecules (Basel, Switzerland), 2021-09, Vol.26 (17), p.5397

2021

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Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1686

2021

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An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease

Hormones and behavior, 2018-02, Vol.98, p.16-21

2018

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Cholinergic Neurons in the Basal Forebrain Promote Wakefulness by Actions on Neighboring Non-Cholinergic Neurons: An Opto-Dialysis Study

The Journal of neuroscience, 2016-02, Vol.36 (6), p.2057-2067

2016

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Diastereoselective hydroalkoxycarbonylation of terpenes and vinyl-estrone

Journal of molecular catalysis. A, Chemical, 2001-01, Vol.165 (1), p.15-21

2001

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Selective Chemoprecipitation and Subsequent Release of Tagged Species for the Analysis of Nitropeptides by Liquid Chromatography–Tandem Mass Spectrometry

Molecular & cellular proteomics, 2011-08, Vol.10 (8), p.M110.002923-M110.002923, Article M110.002923

2011

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The Prodrug DHED Delivers 17β-Estradiol into the Retina for Protection of Retinal Ganglion Cells and Preservation of Visual Function in an Animal Model of Glaucoma

Cells (Basel, Switzerland), 2024-06, Vol.13 (13), p.1126

2024

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Effect of estradiol replacement on hippocampal concentrations of estrogens in aged rhesus macaques maintained on an obesogenic diet

Biochemistry and biophysics reports, 2023-09, Vol.35, p.101548-101548, Article 101548

2023

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17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics

Pharmaceutics, 2020-01, Vol.12 (2), p.101

2020

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Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males

Pharmaceutics, 2021-09, Vol.13 (9), p.1392

2021

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Factors That Contribute to the Misidentification of Tyrosine Nitration by Shotgun Proteomics

Molecular & cellular proteomics, 2008-12, Vol.7 (12), p.2442-2451

2008

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Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model

Pharmaceuticals (Basel, Switzerland), 2020-06, Vol.13 (6), p.119

2020

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Analytical challenges in chemical-enzymatic drug targeting

Advanced drug delivery reviews, 1994-06, Vol.14 (2), p.301-317

Prokai, Laszlo

1994

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Targeted Delivery of Small Interfering RNA Using Reconstituted High-Density Lipoprotein Nanoparticles

Neoplasia (New York, N.Y.), 2011-04, Vol.13 (4), p.309-IN8

2011

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Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

Biochemistry (Easton), 2010-07, Vol.49 (29), p.6263-6275

2010

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Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice

Mannich Ketones as Possible Antimycobacterial Agents

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

Antifungal activity of fused Mannich ketones triggers an oxidative stress response and is Cap1-dependent in Candida albicans

Antifungal unsaturated cyclic Mannich ketones and amino alcohols: Study of mechanism of action

A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy

The impact of 17β-estradiol on the estrogen-deficient female brain: from mechanisms to therapy with hot flushes as target symptoms

Proteomics-Based Identification of Retinal Protein Networks Impacted by Elevated Intraocular Pressure in the Hypertonic Saline Injection Model of Experimental Glaucoma

Application of Screening Experimental Designs to Assess Chromatographic Isotope Effect upon Isotope-Coded Derivatization for Quantitative Liquid Chromatography–Mass Spectrometry

Comparative Proteomics Analysis Reveals Unique Early Signaling Response of Saccharomyces cerevisiae to Oxidants with Different Mechanism of Action

The Antagonist pGlu-βGlu-Pro-NH2 Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor

Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications

An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease

Cholinergic Neurons in the Basal Forebrain Promote Wakefulness by Actions on Neighboring Non-Cholinergic Neurons: An Opto-Dialysis Study

Diastereoselective hydroalkoxycarbonylation of terpenes and vinyl-estrone

Selective Chemoprecipitation and Subsequent Release of Tagged Species for the Analysis of Nitropeptides by Liquid Chromatography–Tandem Mass Spectrometry

The Prodrug DHED Delivers 17β-Estradiol into the Retina for Protection of Retinal Ganglion Cells and Preservation of Visual Function in an Animal Model of Glaucoma

Effect of estradiol replacement on hippocampal concentrations of estrogens in aged rhesus macaques maintained on an obesogenic diet

17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics

Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males

Factors That Contribute to the Misidentification of Tyrosine Nitration by Shotgun Proteomics

Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model

Analytical challenges in chemical-enzymatic drug targeting

Targeted Delivery of Small Interfering RNA Using Reconstituted High-Density Lipoprotein Nanoparticles

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

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