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Role of Placental Nutrient Sensing in Developmental Programming

Clinical obstetrics and gynecology, 2013-09, Vol.56 (3), p.591-601

2013

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Placental function in maternal obesity

Clinical science (1979), 2020-04, Vol.134 (8), p.961

2020

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Developmental origins of metabolic diseases

Physiological reviews, 2021-07, Vol.101 (3), p.739-795

2021

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Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches

Clinical science (1979), 2007-07, Vol.113 (1), p.1

2007

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Regulation of Nutrient Transport across the Placenta

Journal of Pregnancy, 2012-01, Vol.2012, p.179827-14

2012

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Placental Nutrient Transport in Gestational Diabetic Pregnancies

Frontiers in endocrinology (Lausanne), 2017-11, Vol.8, p.306-306

2017

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Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (41), p.12858-12863

2015

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Placental mTOR links maternal nutrient availability to fetal growth

Biochemical Society transactions, 2009-02, Vol.37 (Pt 1), p.295

2009

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Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2

Clinical science (1979), 2016-04, Vol.130 (7), p.499

2016

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Activation of Placental mTOR Signaling and Amino Acid Transporters in Obese Women Giving Birth to Large Babies

The journal of clinical endocrinology and metabolism, 2013-01, Vol.98 (1), p.105-113

2013

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Human placental lipid content and lipid metabolic enzyme abundance in obesity and across gestation

Clinical science (1979), 2022-10, Vol.136 (19), p.1389

2022

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Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Clinical science (1979), 2015-12, Vol.129 (12), p.1131

2015

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Increased glucose and placental GLUT-1 in large infants of obese nondiabetic mothers

American journal of obstetrics and gynecology, 2015-02, Vol.212 (2), p.227.e1-227.e7

2015

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Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

Clinical science (1979), 2020-01, Vol.134 (1), p.53

2020

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Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Scientific reports, 2017-06, Vol.7 (1), p.3982-15, Article 3982

2017

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

Clinical science (1979), 2021-09, Vol.135 (17), p.2049

2021

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Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis

Scientific reports, 2019-01, Vol.9 (1), p.246-246, Article 246

2019

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A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

Clinical science (1979), 2022-11, Vol.136 (21), p.1535

2022

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Full-Length Adiponectin Attenuates Insulin Signaling and Inhibits Insulin-Stimulated Amino Acid Transport in Human Primary Trophoblast Cells

Diabetes (New York, N.Y.), 2010-05, Vol.59 (5), p.1161-1170

2010

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Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

Clinical science (1979), 2020-12, Vol.134 (23), p.3123

2020

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Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7273

2023

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High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

The FASEB journal, 2009-01, Vol.23 (1), p.271-278

2009

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A potential role for lysophosphatidylcholine in the delivery of long chain polyunsaturated fatty acids to the fetal circulation

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-03, Vol.1864 (3), p.394-402

2019

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Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth

The Journal of physiology, 2007-07, Vol.582 (1), p.449-459

2007

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Role of Placental Nutrient Sensing in Developmental Programming

Placental function in maternal obesity

Developmental origins of metabolic diseases

Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches

Regulation of Nutrient Transport across the Placenta

Placental Nutrient Transport in Gestational Diabetic Pregnancies

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Placental mTOR links maternal nutrient availability to fetal growth

Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2

Activation of Placental mTOR Signaling and Amino Acid Transporters in Obese Women Giving Birth to Large Babies

Human placental lipid content and lipid metabolic enzyme abundance in obesity and across gestation

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Increased glucose and placental GLUT-1 in large infants of obese nondiabetic mothers

Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis

A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

Full-Length Adiponectin Attenuates Insulin Signaling and Inhibits Insulin-Stimulated Amino Acid Transport in Human Primary Trophoblast Cells

Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

A potential role for lysophosphatidylcholine in the delivery of long chain polyunsaturated fatty acids to the fetal circulation

Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth

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