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Functional deficit in hippocampal activity during fear extinction recall in the single prolonged-stress model of PTSD in male rats

Behavioural brain research, 2021-01, Vol.396, p.112902-112902, Article 112902

2021

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Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Analytical biochemistry, 2007, Vol.360 (1), p.30-40

2007

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Discovery of biaryls as RORγ inverse agonists by using structure-based design

Bioorganic & medicinal chemistry letters, 2016-05, Vol.26 (10), p.2459-2463

2016

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Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand

BMC structural biology, 2016-06, Vol.16 (1), p.7-7, Article 7

2016

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Novel and selective spiroindoline-based inhibitors of sky kinase

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.190-193

2012

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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.767-772

2013

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Studies on the Total Synthesis of Formamicin: Synthesis of the C(1)−C(11) Fragment

Organic letters, 2001-02, Vol.3 (3), p.453-456

2001

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An improved method for the synthesis of enantiomerically pure amino acid ester isocyanates

Journal of organic chemistry, 1992-12, Vol.57 (26), p.7364-7366

1992

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Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.1051-1055

2013

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Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.1046-1050

2013

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Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Bioorganic & medicinal chemistry, 2007-09, Vol.15 (17), p.5912-5949

2007

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Anti-1,3-diols by Addition of Dialkylzinc Reagents to 4-Acetoxy-1,3-dioxanes

Journal of organic chemistry, 1999-03, Vol.64 (6), p.2026-2037

1999

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Total Synthesis of Formamicin

Journal of the American Chemical Society, 2004-08, Vol.126 (30), p.9307-9317

2004

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Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3575-3580

2007

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Ketopiperazine-based renin inhibitors: Optimization of the “C” ring

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2500-2504

2006

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The discovery and preparation of disubstituted novel amino-aryl-piperidine-based renin inhibitors

Bioorganic & medicinal chemistry, 2005-01, Vol.13 (1), p.59-68

2005

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Discovery of novel non-peptidic ketopiperazine-based renin inhibitors

Bioorganic & medicinal chemistry, 2005-04, Vol.13 (7), p.2657-2664

2005

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Benzyl ether structure–activity relationships in a series of ketopiperazine-based renin inhibitors

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4713-4716

2005

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Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2371-2374

2005

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Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

Organic letters, 2004-10, Vol.6 (22), p.4069-4072

2004

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Dialkylzinc Additions to 4-Acetoxy-1,3-dioxanes: A Highly Stereoselective Route to Protected anti-1,3-Diols

Journal of organic chemistry, 1997-09, Vol.62 (19), p.6460-6461

1997

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Highly Diastereoselective Synthesis of Propargylic 1,2-a nti-Diol Derivatives Using α-Alkoxypropargylstannanes

Organic letters, 2001-09, Vol.3 (19), p.3057-3060

2001

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In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

MedChemComm, 2016-01, Vol.7 (6), p.1093-1101

2016

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Optimization of a Pd-catalyzed intramolecular α-arylation synthesis of tricyclo-[7.3.1.0 2,7]-trideca-2,4,6-trien-13-ones

Tetrahedron letters, 2010-08, Vol.51 (33), p.4441-4444

2010

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In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agentsThe authors declare no competing interests.Electronic supplementary information (ESI) available: Supplementary data associated with this article can be found in the online version. See DOI: 10.1039/c6md00128a

2016-06

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Functional deficit in hippocampal activity during fear extinction recall in the single prolonged-stress model of PTSD in male rats

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Discovery of biaryls as RORγ inverse agonists by using structure-based design

Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand

Novel and selective spiroindoline-based inhibitors of sky kinase

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ

Studies on the Total Synthesis of Formamicin: Synthesis of the C(1)−C(11) Fragment

An improved method for the synthesis of enantiomerically pure amino acid ester isocyanates

Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Anti-1,3-diols by Addition of Dialkylzinc Reagents to 4-Acetoxy-1,3-dioxanes

Total Synthesis of Formamicin

Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors

Ketopiperazine-based renin inhibitors: Optimization of the “C” ring

The discovery and preparation of disubstituted novel amino-aryl-piperidine-based renin inhibitors

Discovery of novel non-peptidic ketopiperazine-based renin inhibitors

Benzyl ether structure–activity relationships in a series of ketopiperazine-based renin inhibitors

Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

Dialkylzinc Additions to 4-Acetoxy-1,3-dioxanes: A Highly Stereoselective Route to Protected anti-1,3-Diols

Highly Diastereoselective Synthesis of Propargylic 1,2-a nti-Diol Derivatives Using α-Alkoxypropargylstannanes

In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

Optimization of a Pd-catalyzed intramolecular α-arylation synthesis of tricyclo-[7.3.1.0 2,7]-trideca-2,4,6-trien-13-ones

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