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A quantitative systems pharmacology modeling platform for evaluating triglyceride profiles in patients with high triglycerides receiving evinacumab

CPT: pharmacometrics and systems pharmacology, 2021-11, Vol.10 (11), p.1332-1342

2021

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The skeletal structure of insulin-like growth factor I-deficient mice

Journal of bone and mineral research, 2001-12, Vol.16 (12), p.2320-2329

2001

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Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity

Endocrinology (Philadelphia), 2002-05, Vol.143 (5), p.1741-1747

2002

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Towards the enantioselective synthesis of (-)-euonyminol--preparation of a fully functionalised lower-rim model

Organic & biomolecular chemistry, 2013-04, Vol.11 (15), p.2514-2533

2013

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Fulvestrant: From the Laboratory to Commercial-Scale Manufacture

Organic process research & development, 2010-05, Vol.14 (3), p.544-552

2010

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Significant rate enhancement via potassium pivalate in a Miyaura borylation approach to verinurad

Tetrahedron letters, 2020-03, Vol.61 (10), p.151589, Article 151589

2020

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Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

Neuron (Cambridge, Mass.), 1995-04, Vol.14 (4), p.717-730

1995

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Corrigendum to “Significant rate enhancement via potassium pivalate in a Miyaura borylation approach to verinurad” [Tetrahedron Lett. 61 (2020) 151589]

Tetrahedron letters, 2020-07, Vol.61 (29), p.152027, Article 152027

2020

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A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet

Nature medicine, 1998-08, Vol.4 (8), p.934-938

1998

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Stanniocalcin 1 Alters Muscle and Bone Structure and Function in Transgenic Mice

Endocrinology (Philadelphia), 2002-09, Vol.143 (9), p.3681-3690

2002

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The Apoe-/- Mouse PhysioLab® Platform: A Validated Physiologically-based Mathematical Model of Atherosclerotic Plaque Progression in the Apoe-/- Mouse

Biodiscovery, 2012-09, Vol.3, p.1-13

2012

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Development of an SNAr Reaction: A Practical and Scalable Strategy To Sequester and Remove HF

Organic process research & development, 2018-09, Vol.22 (9), p.1086-1091

2018

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Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

Physiological genomics, 2002-12, Vol.11 (3), p.263-272

2002

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Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones

Chemical communications (Cambridge, England), 2014-01, Vol.50 (6), p.743-746

2014

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Development of an S N Ar Reaction: A Practical and Scalable Strategy To Sequester and Remove HF

Organic process research & development, 2018-09, Vol.22 (9), p.1086-1091

2018

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Development of the Convergent, Kilogram-Scale Synthesis of an Antibacterial Clinical Candidate Using Enantioselective Hydrogenation

Organic process research & development, 2020-04, Vol.24 (4), p.588-598

2020

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Process Development, Manufacture, and Understanding of the Atropisomerism and Polymorphism of Verinurad

Organic process research & development, 2022-03, Vol.26 (3), p.936-948

2022

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Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketonesElectronic supplementary information (ESI) available: 1H and 13C NMR spectra for all novel compounds and compounds prepared by a novel protocols. See DOI: 10.1039/c3cc47967f

2013-12

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Abstract 9560: Clinical Trial Simulations of Dyslipidemic Patients in a Mechanistic Model of Cardiovascular Disease Predict Little Impact on CHD Events by CETP Inhibitors

Circulation (New York, N.Y.), 2011-11, Vol.124 (suppl_21)

2011

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Improved synthesis of substituted pyrido[2,3-d]pyrimidinediones

Tetrahedron letters, 2011-07, Vol.52 (28), p.3657-3661

2011

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A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

Cell, 1987-09, Vol.50 (6), p.831-840

1987

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Dialkyl Sulfide Stabilisation in a Catalytic Dicuprate 1,6-Dienone Addition Process

Organic process research & development, 2011-01, Vol.15 (1), p.49-52

2011

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Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy

Metabolism, clinical and experimental, 2003-07, Vol.52 (7), p.916-921

2003

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Development of a Catalytic Cuprate 1,6-Conjugate Dienone Addition Process for the Manufacture of Fulvestrant EAS, a Key Intermediate in the Synthesis of Fulvestrant

Organic process research & development, 2010-09, Vol.14 (5), p.1188-1193

2010

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Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48

The Journal of biological chemistry, 1996-04, Vol.271 (17), p.9887-9890

1996

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A quantitative systems pharmacology modeling platform for evaluating triglyceride profiles in patients with high triglycerides receiving evinacumab

The skeletal structure of insulin-like growth factor I-deficient mice

Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity

Towards the enantioselective synthesis of (-)-euonyminol--preparation of a fully functionalised lower-rim model

Fulvestrant: From the Laboratory to Commercial-Scale Manufacture

Significant rate enhancement via potassium pivalate in a Miyaura borylation approach to verinurad

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

Corrigendum to “Significant rate enhancement via potassium pivalate in a Miyaura borylation approach to verinurad” [Tetrahedron Lett. 61 (2020) 151589]

A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet

Stanniocalcin 1 Alters Muscle and Bone Structure and Function in Transgenic Mice

The Apoe-/- Mouse PhysioLab® Platform: A Validated Physiologically-based Mathematical Model of Atherosclerotic Plaque Progression in the Apoe-/- Mouse

Development of an SNAr Reaction: A Practical and Scalable Strategy To Sequester and Remove HF

Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones

Development of an S N Ar Reaction: A Practical and Scalable Strategy To Sequester and Remove HF

Development of the Convergent, Kilogram-Scale Synthesis of an Antibacterial Clinical Candidate Using Enantioselective Hydrogenation

Process Development, Manufacture, and Understanding of the Atropisomerism and Polymorphism of Verinurad

Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketonesElectronic supplementary information (ESI) available: 1H and 13C NMR spectra for all novel compounds and compounds prepared by a novel protocols. See DOI: 10.1039/c3cc47967f

Abstract 9560: Clinical Trial Simulations of Dyslipidemic Patients in a Mechanistic Model of Cardiovascular Disease Predict Little Impact on CHD Events by CETP Inhibitors

Improved synthesis of substituted pyrido[2,3-d]pyrimidinediones

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

Dialkyl Sulfide Stabilisation in a Catalytic Dicuprate 1,6-Dienone Addition Process

Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy

Development of a Catalytic Cuprate 1,6-Conjugate Dienone Addition Process for the Manufacture of Fulvestrant EAS, a Key Intermediate in the Synthesis of Fulvestrant

Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48

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