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Carbohydrate Sensing Through the Transcription Factor ChREBP

Frontiers in genetics, 2019-06, Vol.10, p.472-472

2019

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Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

The Journal of clinical investigation, 2008-03, Vol.118 (3), p.829-838

2008

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Sweet Sixteenth for ChREBP: Established Roles and Future Goals

Cell metabolism, 2017-08, Vol.26 (2), p.324-341

2017

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Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

The Journal of clinical investigation, 2010-12, Vol.120 (12), p.4316-4331

2010

Volltextzugriff (PDF)

Hepatokines: unlocking the multi-organ network in metabolic diseases

Diabetologia, 2015-08, Vol.58 (8), p.1699-1703

2015

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Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors

Biochimica et biophysica acta, 2011-08, Vol.1812 (8), p.995-1006

2011

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The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

The Journal of clinical investigation, 2012-06, Vol.122 (6), p.2176-2194

2012

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Editorial: The liver as an endocrine organ: Hepatokines and ketone bodies, novel hormones to be acknowledged

Frontiers in endocrinology (Lausanne), 2023-01, Vol.13, p.1117773-1117773

2023

Volltextzugriff (PDF)

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

Journal of hepatology, 2012-01, Vol.56 (1), p.199-209

2012

Volltextzugriff (PDF)

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Nature communications, 2018-05, Vol.9 (1), p.2092-18, Article 2092

2018

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Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

Molecular and Cellular Biology, 2013-06, Vol.33 (11), p.2202-2211

2013

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The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

Nature communications, 2024-02, Vol.15 (1), p.1879-1879, Article 1879

2024

Volltextzugriff (PDF)

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

Diabetes (New York, N.Y.), 2011-05, Vol.60 (5), p.1399-1413

2011

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Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity Associated Type 2 Diabetes

Diabetes (New York, N.Y.), 2018-07, Vol.67 (7), p.1310-1321

2018

Volltextzugriff (PDF)

MondoA/ChREBP: The usual suspects of transcriptional glucose sensing; Implication in pathophysiology

Metabolism, clinical and experimental, 2017-05, Vol.70, p.133-151

2017

Volltextzugriff (PDF)

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

Diabetes (New York, N.Y.), 2019-02, Vol.68 (2), p.305-317

2019

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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Cell reports (Cambridge), 2017-10, Vol.21 (2), p.403-416

2017

Volltextzugriff (PDF)

Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

Diabetes (New York, N.Y.), 2006-08, Vol.55 (8), p.2159-2170

2006

Volltextzugriff (PDF)

ChREBP, a transcriptional regulator of glucose and lipid metabolism

Annual review of nutrition, 2007-01, Vol.27 (1), p.179-192

2007

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New insights into the inter-organ crosstalk mediated by ChREBP

Frontiers in endocrinology (Lausanne), 2023-02, Vol.14, p.1095440-1095440

2023

Volltextzugriff (PDF)

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

Hepatology (Baltimore, Md.), 2015-10, Vol.62 (4), p.1086-1100

2015

Volltextzugriff (PDF)

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

Journal of hepatology, 2011-07, Vol.55 (1), p.145-153

2011

Volltextzugriff (PDF)

Role of ChREBP in hepatic steatosis and insulin resistance

FEBS letters, 2008-01, Vol.582 (1), p.68-73

2008

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Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

PloS one, 2017-07, Vol.12 (7), p.e0181393-e0181393

2017

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Carbohydrate Sensing Through the Transcription Factor ChREBP

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

Sweet Sixteenth for ChREBP: Established Roles and Future Goals

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

Hepatokines: unlocking the multi-organ network in metabolic diseases

Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

Editorial: The liver as an endocrine organ: Hepatokines and ketone bodies, novel hormones to be acknowledged

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity Associated Type 2 Diabetes

MondoA/ChREBP: The usual suspects of transcriptional glucose sensing; Implication in pathophysiology

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

ChREBP, a transcriptional regulator of glucose and lipid metabolism

New insights into the inter-organ crosstalk mediated by ChREBP

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

Role of ChREBP in hepatic steatosis and insulin resistance

Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

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