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A selective orexin-1 receptor antagonist reduces food consumption in male and female rats

Regulatory peptides, 2000-12, Vol.96 (1), p.45-51

2000

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Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14897-14911

2023

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Discovery of a series of ester-substituted NLRP3 inflammasome inhibitors

Bioorganic & medicinal chemistry letters, 2020-12, Vol.30 (23), p.127560-127560, Article 127560

2020

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1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1907-1910

2001

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Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3299-3319

2021

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Progress in the development of neurokinin 3 modulators for the treatment of schizophrenia: molecule development and clinical progress

Future medicinal chemistry, 2013-09, Vol.5 (13), p.1525-1546

2013

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Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin‑2 Receptor

ACS pharmacology & translational science, 2020-08, Vol.3 (4), p.706-719

2020

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1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1741-1745

2007

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Structure–activity analysis of truncated orexin-A analogues at the orexin-1 receptor

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.737-740

2001

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Synthesis of substituted 2-mercaptobenzaldehydes and 2-substituted benzo[ b]thiophenes

Tetrahedron letters, 2000-07, Vol.41 (28), p.5415-5418

2000

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Asymmetric oxidation of dithiane derivatives: Enantiomerically pure 1,3-dithiane 1-oxide

Tetrahedron: asymmetry, 1993-10, Vol.4 (10), p.2139-2142

1993

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Structural requirements of olefinic 5-substituted deoxyuridines for antiherpes activity

Journal of medicinal chemistry, 1983-09, Vol.26 (9), p.1252-1257

1983

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Thromboxane synthase inhibitors. Synthesis and pharmacological activity of (R)-, (S)-, and (.+-.)-2,2-dimethyl-6-[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl]ethoxy]hexanoic acids

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1812-1818

1987

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An unexpected rearrangement of 4-alkylaminoindoles

Journal of the Chemical Society. Chemical communications, 1982 (23), p.1356

1982

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Synthestic approaches to the teleocidin-related tumour promoters: a total synthesis of (±)-indolactam V

Journal of the Chemical Society. Chemical communications, 1986 (4), p.344-346

1986

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A Model for the Synthesis of the Tigliane and Daphnane Diterpenes Using an Intramolecular Diels-Alder Reaction

Synlett, 1991-07, Vol.1991 (7), p.472-474

1991

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ChemInform Abstract: Synthesis of Substituted 2-Mercaptobenzaldehydes and 2-Substituted Benzo[b]thiophenes

ChemInform, 2000-09, Vol.31 (39), p.no-no

2000

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Dibenzoquinazoline diones as antihypertensive cyclic guanosine monophosphate phosphodiesterase inhibitors

Biochemical pharmacology, 1987-10, Vol.36 (20), p.3517-3521

1987

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Synthetic approaches to the teleocidin-related tumour promoters: a total synthesis of (±)-indolactam V

Journal of the Chemical Society. Chemical communications, 1986-02 (4), p.344-346

1986

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Major Update: Remdesivir for Adults With COVID-19 : A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

Annals of internal medicine, 2021-05, Vol.174 (5), p.663

2021

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Remdesivir for Adults With COVID-19 : A Living Systematic Review for American College of Physicians Practice Points

Annals of internal medicine, 2021-02, Vol.174 (2), p.209

2021

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Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

Annals of internal medicine, 2022-05, Vol.175 (5), p.701

2022

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Deep-sea mining of seafloor massive sulfides

Marine policy, 2010-05, Vol.34 (3), p.728-732

2010

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A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

Scientific reports, 2019-01, Vol.9 (1), p.201, Article 201

2019

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A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process

The lancet child & adolescent health, 2021-02, Vol.5 (2), p.133-141

2021

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A selective orexin-1 receptor antagonist reduces food consumption in male and female rats

Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

Discovery of a series of ester-substituted NLRP3 inflammasome inhibitors

1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization

Progress in the development of neurokinin 3 modulators for the treatment of schizophrenia: molecule development and clinical progress

Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin‑2 Receptor

1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1

Structure–activity analysis of truncated orexin-A analogues at the orexin-1 receptor

Synthesis of substituted 2-mercaptobenzaldehydes and 2-substituted benzo[ b]thiophenes

Asymmetric oxidation of dithiane derivatives: Enantiomerically pure 1,3-dithiane 1-oxide

Structural requirements of olefinic 5-substituted deoxyuridines for antiherpes activity

Thromboxane synthase inhibitors. Synthesis and pharmacological activity of (R)-, (S)-, and (.+-.)-2,2-dimethyl-6-[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl]ethoxy]hexanoic acids

An unexpected rearrangement of 4-alkylaminoindoles

Synthestic approaches to the teleocidin-related tumour promoters: a total synthesis of (±)-indolactam V

A Model for the Synthesis of the Tigliane and Daphnane Diterpenes Using an Intramolecular Diels-Alder Reaction

ChemInform Abstract: Synthesis of Substituted 2-Mercaptobenzaldehydes and 2-Substituted Benzo[b]thiophenes

Dibenzoquinazoline diones as antihypertensive cyclic guanosine monophosphate phosphodiesterase inhibitors

Synthetic approaches to the teleocidin-related tumour promoters: a total synthesis of (±)-indolactam V

Major Update: Remdesivir for Adults With COVID-19 : A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

Remdesivir for Adults With COVID-19 : A Living Systematic Review for American College of Physicians Practice Points

Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

Deep-sea mining of seafloor massive sulfides

A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process

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