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Signals that regulate food intake and energy homeostasis

Science (American Association for the Advancement of Science), 1998-05, Vol.280 (5368), p.1378-1383

1998

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Central nervous system control of food intake

Nature (London), 2000-04, Vol.404 (6778), p.661-671

2000

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Insulin in the brain : a hormonal regulator of energy balance

Endocrine reviews, 1992-08, Vol.13 (3), p.387-414

1992

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Obesity, diabetes and the central nervous system

Diabetologia, 1998-08, Vol.41 (8), p.863-881

1998

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Saturable transport of insulin from plasma into the central nervous system of dogs in vivo : a mechanism for regulated insulin delivery to the brain

The Journal of clinical investigation, 1993-10, Vol.92 (4), p.1824-1830

1993

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beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms

Diabetes (New York, N.Y.), 2001-02, Vol.50 (suppl 1), p.S160-S163

2001

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Localization of insulin receptor mRNA in rat brain by in situ hybridization

Endocrinology (Philadelphia), 1990-12, Vol.127 (6), p.3234-3236

1990

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Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

Neurology, 1998-01, Vol.50 (1), p.164-168

1998

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Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

Diabetes (New York, N.Y.), 1996-04, Vol.45 (4), p.531-535

1996

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Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight

Brain research, 1999-11, Vol.848 (1-2), p.114-123

1999

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Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

Nature medicine, 1996-05, Vol.2 (5), p.589-593

1996

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Evidence that plasma leptin and insulin levels are associated with body adiposity via different mechanisms

Diabetes care, 1997-09, Vol.20 (9), p.1476-1481

1997

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The evaluation of insulin as a metabolic signal influencing behavior via the brain

Neuroscience and biobehavioral reviews, 1996, Vol.20 (1), p.139-144

1996

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Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) zucker rats

Endocrinology (Philadelphia), 1991-05, Vol.128 (5), p.2645-2647

1991

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Diabetes Complications: Why is Glucose Potentially Toxic?

Science (American Association for the Advancement of Science), 1996-05, Vol.272 (5262), p.699-700

1996

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Diabetes, obesity, and the brain

Science (American Association for the Advancement of Science), 2005-01, Vol.307 (5708), p.375-379

2005

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Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

The journal of clinical endocrinology and metabolism, 1998-02, Vol.83 (2), p.604-608

1998

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Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs : quantitative aspects and implications for transport

The Journal of clinical investigation, 1991-10, Vol.88 (4), p.1272-1281

1991

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Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus

The journal of clinical endocrinology and metabolism, 1990-05, Vol.70 (5), p.1247-1253

1990

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Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function

The journal of clinical endocrinology and metabolism, 1985, Vol.60 (1), p.13-20

1985

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Insulin resistance and β-cell dysfunction in aging: the importance of dietary carbohydrate

The journal of clinical endocrinology and metabolism, 1988-11, Vol.67 (5), p.951-957

1988

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Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man

The journal of clinical endocrinology and metabolism, 1987, Vol.64 (1), p.190-194

1987

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Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs

Diabetes (New York, N.Y.), 1996-01, Vol.45 (1), p.86-90

1996

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Effect of troglitazone on B cell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus

The journal of clinical endocrinology and metabolism, 1998-03, Vol.83 (3), p.819-823

1998

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Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose

The journal of clinical endocrinology and metabolism, 1990-10, Vol.71 (4), p.994-1002

1990

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Signals that regulate food intake and energy homeostasis

Central nervous system control of food intake

Insulin in the brain : a hormonal regulator of energy balance

Obesity, diabetes and the central nervous system

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo : a mechanism for regulated insulin delivery to the brain

beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms

Localization of insulin receptor mRNA in rat brain by in situ hybridization

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight

Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

Evidence that plasma leptin and insulin levels are associated with body adiposity via different mechanisms

The evaluation of insulin as a metabolic signal influencing behavior via the brain

Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) zucker rats

Diabetes Complications: Why is Glucose Potentially Toxic?

Diabetes, obesity, and the brain

Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs : quantitative aspects and implications for transport

Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus

Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function

Insulin resistance and β-cell dysfunction in aging: the importance of dietary carbohydrate

Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man

Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs

Effect of troglitazone on B cell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus

Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose

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