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Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery

Molecular therapy. Methods & clinical development, 2020-03, Vol.16, p.204-224

2020

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Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease

Scientific reports, 2024-01, Vol.14 (1), p.276-276, Article 276

2024

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Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies

Frontiers in immunology, 2022-09, Vol.13, p.1011143-1011143

2022

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The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation

Stem cell research, 2015-07, Vol.15 (1), p.96-108

2015

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Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity

Nature communications, 2023-07, Vol.14 (1), p.4206-4206, Article 4206

2023

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Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels

Frontiers in immunology, 2022-12, Vol.13, p.1070476-1070476

2022

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Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII

Frontiers in immunology, 2022-12, Vol.13, p.954984

2022

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In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application

Molecular therapy. Methods & clinical development, 2016-01, Vol.5 (C), p.16020-16020, Article 16020

2016

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Mesenchymal stem cells engineered to inhibit complement-mediated damage

PloS one, 2013-03, Vol.8 (3), p.e60461-e60461

2013

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Simulated microgravity impairs human NK cell cytotoxic activity against space radiation-relevant leukemic cells

NPJ microgravity, 2024-08, Vol.10 (1), p.85-10

2024

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Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins

PloS one, 2012-05, Vol.7 (5), p.e36163-e36163

2012

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Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery

Advanced drug delivery reviews, 2010-09, Vol.62 (12), p.1156-1166

2010

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Deconstructed Microfluidic Bone Marrow On‐A‐Chip to Study Normal and Malignant Hemopoietic Cell–Niche Interactions

Small (Weinheim an der Bergstrasse, Germany), 2019-10, Vol.15 (43), p.e1902971-n/a

2019

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Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC

Experimental hematology, 2011-12, Vol.39 (12), p.1124-1135.e4

2011

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Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model

Hepatology (Baltimore, Md.), 2012-09, Vol.56 (3), p.1086-1096

2012

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Trial offers hope to children with hypoplastic left heart syndrome

Molecular therapy, 2024-03, Vol.32 (3), p.565-565

2024

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Curcumin Nanodiscs Improve Solubility and Serve as Radiological Protectants against Ionizing Radiation Exposures in a Cell-Cycle Dependent Manner

Nanomaterials (Basel, Switzerland), 2022-10, Vol.12 (20), p.3619

2022

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Characterization of naturally-occurring humoral immunity to AAV in sheep

PloS one, 2013-09, Vol.8 (9), p.e75142-e75142

2013

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Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.465-477

2020

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Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A

Frontiers in cell and developmental biology, 2021-08, Vol.9, p.678117-678117

2021

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Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

Stem cell reports, 2016-06, Vol.6 (6), p.957-969

2016

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Development and characterization of recombinant ovine coagulation factor VIII

PloS one, 2012-11, Vol.7 (11), p.e49481

2012

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Hemophilia A: an ideal disease to correct in utero

Frontiers in pharmacology, 2014-12, Vol.5, p.276-276

2014

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Immediate effects of acute Mars mission equivalent doses of SEP and GCR radiation on the murine gastrointestinal system-protective effects of curcumin-loaded nanolipoprotein particles (cNLPs)

Frontiers in astronomy and space sciences, 2023, Vol.10

2023

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Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A

Frontiers in bioengineering and biotechnology, 2021-03, Vol.9, p.639070-639070

2021

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Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery

Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease

Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies

The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation

Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity

Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels

Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII

In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application

Mesenchymal stem cells engineered to inhibit complement-mediated damage

Simulated microgravity impairs human NK cell cytotoxic activity against space radiation-relevant leukemic cells

Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins

Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery

Deconstructed Microfluidic Bone Marrow On‐A‐Chip to Study Normal and Malignant Hemopoietic Cell–Niche Interactions

Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC

Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model

Trial offers hope to children with hypoplastic left heart syndrome

Curcumin Nanodiscs Improve Solubility and Serve as Radiological Protectants against Ionizing Radiation Exposures in a Cell-Cycle Dependent Manner

Characterization of naturally-occurring humoral immunity to AAV in sheep

Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A

Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A

Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

Development and characterization of recombinant ovine coagulation factor VIII

Hemophilia A: an ideal disease to correct in utero

Immediate effects of acute Mars mission equivalent doses of SEP and GCR radiation on the murine gastrointestinal system-protective effects of curcumin-loaded nanolipoprotein particles (cNLPs)

Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A

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