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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1034-1040

2000

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Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor

Antimicrobial Agents and Chemotherapy, 1997-05, Vol.41 (5), p.1058-1063

1997

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Nonnucleoside Reverse Transcriptase Inhibitors that Potently and Specifically Block Human Immunodeficiency Virus Type 1 Replication

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (19), p.8806-8810

1991

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A Mutation in Reverse Transcriptase of Bis(heteroaryl)Piperazine-Resistant Human Immunodeficiency Virus Type 1 that Confers Increased Sensitivity to Other Nonnucleoside Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4713-4717

1993

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U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication

Antimicrobial Agents and Chemotherapy, 1993-05, Vol.37 (5), p.1127-1131

1993

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Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Journal of medicinal chemistry, 1998-09, Vol.41 (20), p.3793-3803

1998

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Oxazolidinone Antibiotics Target the P Site on Escherichia coli Ribosomes

Antimicrobial Agents and Chemotherapy, 2002-04, Vol.46 (4), p.1080-1085

2002

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(-)-6-chloro-2-[(1-furo[2,3-c]pyridin-5-yl-ethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1357-1360

1998

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Creatinine synthesis rate and muscle strength and self-reported physical health in dialysis patients

Clinical nutrition (Edinburgh, Scotland), 2020-05, Vol.39 (5), p.1600-1607

2020

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Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Journal of medicinal chemistry, 1996-10, Vol.39 (22), p.4349-4353

1996

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(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes

Journal of Virology, 1996-06, Vol.70 (6), p.3698-3705

1996

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Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing

Teratogenesis, carcinogenesis, and mutagenesis, 1984, Vol.4 (2), p.181-188

1984

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Validation of a quantitative RNA PCR assay for HIV-1 in human plasma

Journal of clinical laboratory analysis, 1996, Vol.10 (5), p.262-268

1996

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A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

Biochemistry (Easton), 1996-07, Vol.35 (30), p.9737-9745

1996

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Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

Biochemistry (Easton), 1996-02, Vol.35 (6), p.1911-1917

1996

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The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

The Journal of biological chemistry, 1995-06, Vol.270 (22), p.13573-13579

1995

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Developmental toxicity of bropirimine in rats after oral administration

Teratology (Philadelphia), 1988-07, Vol.38 (1), p.7-14

1988

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Reproductive and developmental effects on rats after prenatal, postnatal, or pre- and postnatal exposure to the hypotensive agent losulazine

Teratology (Philadelphia), 1987-10, Vol.36 (2), p.171-180

1987

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(Alkylamino)piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 sub(IIIB) with reduced replication phenotypes

Journal of virology, 1996-01, Vol.70 (6), p.3698-3705

1996

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Postnatal behavioral effects of ochratoxin a in offspring of treated mice

Teratology (Philadelphia), 1983-06, Vol.27 (3), p.293-300

1983

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Nonnucleoside reverse transcriptase inhibitors that potently and specificity block human immonodeficiency virus type 1 replication

Proceedings of the National Academy of Sciences - PNAS, 1991, Vol.88 (19), p.8806-8810

1991

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Developmental toxicity of bropivimine in rats after oral administration

Teratology (Philadelphia), 1988, Vol.38 (1), p.7-14

1988

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The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data

International Journal of Obesity, 2014-08, Vol.38 (8), p.1110-1114

2014

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Theory and Practice of Thermal Transient Testing of Electronic Components

1, 2023

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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor

Nonnucleoside Reverse Transcriptase Inhibitors that Potently and Specifically Block Human Immunodeficiency Virus Type 1 Replication

A Mutation in Reverse Transcriptase of Bis(heteroaryl)Piperazine-Resistant Human Immunodeficiency Virus Type 1 that Confers Increased Sensitivity to Other Nonnucleoside Inhibitors

U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication

Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Oxazolidinone Antibiotics Target the P Site on Escherichia coli Ribosomes

(-)-6-chloro-2-[(1-furo[2,3-c]pyridin-5-yl-ethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor

Creatinine synthesis rate and muscle strength and self-reported physical health in dialysis patients

Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes

Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing

Validation of a quantitative RNA PCR assay for HIV-1 in human plasma

A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

Developmental toxicity of bropirimine in rats after oral administration

Reproductive and developmental effects on rats after prenatal, postnatal, or pre- and postnatal exposure to the hypotensive agent losulazine

(Alkylamino)piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 sub(IIIB) with reduced replication phenotypes

(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor

Postnatal behavioral effects of ochratoxin a in offspring of treated mice

Nonnucleoside reverse transcriptase inhibitors that potently and specificity block human immonodeficiency virus type 1 replication

Developmental toxicity of bropivimine in rats after oral administration

The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data

Theory and Practice of Thermal Transient Testing of Electronic Components

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