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Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia

Immunological reviews, 2020-03, Vol.294 (1), p.92-105

2020

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Enhanced Innate and Acquired Immune Responses in Systemic Sclerosis Primary Peripheral Blood Mononuclear Cells (PBMCs)

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14438

2023

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GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells

Scientific reports, 2024-02, Vol.14 (1), p.3565-3565, Article 3565

2024

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TERT rs2736100 A>C SNP and JAK2 46/1 haplotype significantly contribute to the occurrence of JAK2 V617F and CALR mutated myeloproliferative neoplasms – a multicentric study on 529 patients

British journal of haematology, 2016-07, Vol.174 (2), p.218-226

2016

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Hyperuricemia remodels the serum proteome toward a higher inflammatory state

iScience, 2023-10, Vol.26 (10), p.107909-107909, Article 107909

2023

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Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination

Vaccines (Basel), 2024-07, Vol.12 (7), p.736

2024

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Trained immunity and inflammation in rheumatic diseases

Joint, bone, spine : revue du rhumatisme, 2022-07, Vol.89 (4), p.105364-105364, Article 105364

2022

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Downregulation of type I interferon signalling pathway by urate in primary human PBMCs

Immunology, 2024-10

2024

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The future clinical implications of trained immunity

Expert review of clinical immunology, 2022-11, Vol.18 (11), p.1125-1134

2022

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Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells

Joint, bone, spine : revue du rhumatisme, 2024-05, Vol.91 (3), p.105698-105698, Article 105698

2024

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Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter

Case reports in hematology, 2014-01, Vol.2014 (2014), p.1-3

2014

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Modest contribution of JAK2 V617F allele burden to the occurrence of major thrombosis in polycthemia vera and essential thrombocythemia

Blood cells, molecules, & diseases, 2018-11, Vol.73, p.45-46

2018

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Cholelithiasis in Patients with Gaucher Disease type 1: Risk Factors and the Role of ABCG5/ABCG8 Gene Variants

Journal of gastrointestinal and liver diseases : JGLD, 2016-12, Vol.25 (4), p.447-455

2016

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Gene variants of osteoprotegerin, estrogen-, calcitonin- and vitamin D-receptor genes and serum markers of bone metabolism in patients with Gaucher disease type 1

Therapeutics and clinical risk management, 2018-01, Vol.14, p.2069-2080

2018

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The glucocorticoid receptor A3669G SNP is not associated with polycythemia vera, essential thrombocythemia or primary myelofibrosis

Leukemia & lymphoma, 2016-01, Vol.57 (1), p.209-211

2016

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The role of NOS2A -954G/C and vascular endothelial growth factor +936C/T polymorphisms in type 2 diabetes mellitus and diabetic nonproliferative retinopathy risk management

Therapeutics and clinical risk management, 2015-01, Vol.11 (default), p.1743-1748

2015

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TET2 rs1548483 SNP Associating with Susceptibility to Molecularly Annotated Polycythemia Vera and Primary Myelofibrosis

Journal of personalized medicine, 2020-12, Vol.10 (4), p.259

2020

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The C677T Variant in the Methylenetetrahydrofolate Reductase Gene and Idiopathic Spontaneous Abortion in a Romanian Population Group

Notulae scientia biologicae, 2012-02, Vol.4 (1), p.7-11

2012

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TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Arthritis research & therapy, 2023-02, Vol.25 (1), p.30-30, Article 30

2023

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Among a panel of polymorphisms in genes related to oxidative stress, CAT-262 C>T, GPX1 Pro198Leu and GSTP1 Ile105Val influence the risk of developing BCR-ABL negative myeloproliferative neoplasms

Hematology (Luxembourg), 2016-10, Vol.21 (9), p.520-525

2016

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The relationship between factor V Leiden, prothrombin G20210A, and MTHFR mutations and the first major thrombotic episode in polycythemia vera and essential thrombocythemia

Annals of hematology, 2014-02, Vol.93 (2), p.203-209

2014

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G allele of the JAK2 rs10974944 SNP, part of JAK2 46/1 haplotype, is strongly associated with JAK2 V617F-positive myeloproliferative neoplasms

Annals of hematology, 2010-10, Vol.89 (10), p.979-983

2010

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The XRCC1 Arg194Trp polymorphism is significantly associated with lung adenocarcinoma: a case-control study in an Eastern European Caucasian group

OncoTargets and therapy, 2015-01, Vol.8, p.3533-3538

2015

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Development of a reliable PCR-RFLP assay for investigation of the JAK2 rs10974944 SNP, which might predispose to the acquisition of somatic mutation JAK2(V617F)

Acta haematologica, 2010-01, Vol.123 (2), p.84-87

2010

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Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia

Enhanced Innate and Acquired Immune Responses in Systemic Sclerosis Primary Peripheral Blood Mononuclear Cells (PBMCs)

GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells

MECOM, HBS1L‐MYB, THRB‐RARB, JAK2, and TERT polymorphisms defining the genetic predisposition to myeloproliferative neoplasms: A study on 939 patients

TERT rs2736100 A>C SNP and JAK2 46/1 haplotype significantly contribute to the occurrence of JAK2 V617F and CALR mutated myeloproliferative neoplasms – a multicentric study on 529 patients

Hyperuricemia remodels the serum proteome toward a higher inflammatory state

Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination

Trained immunity and inflammation in rheumatic diseases

Downregulation of type I interferon signalling pathway by urate in primary human PBMCs

The future clinical implications of trained immunity

Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells

Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter

Modest contribution of JAK2 V617F allele burden to the occurrence of major thrombosis in polycthemia vera and essential thrombocythemia

Cholelithiasis in Patients with Gaucher Disease type 1: Risk Factors and the Role of ABCG5/ABCG8 Gene Variants

Gene variants of osteoprotegerin, estrogen-, calcitonin- and vitamin D-receptor genes and serum markers of bone metabolism in patients with Gaucher disease type 1

The glucocorticoid receptor A3669G SNP is not associated with polycythemia vera, essential thrombocythemia or primary myelofibrosis

The role of NOS2A -954G/C and vascular endothelial growth factor +936C/T polymorphisms in type 2 diabetes mellitus and diabetic nonproliferative retinopathy risk management

TET2 rs1548483 SNP Associating with Susceptibility to Molecularly Annotated Polycythemia Vera and Primary Myelofibrosis

The C677T Variant in the Methylenetetrahydrofolate Reductase Gene and Idiopathic Spontaneous Abortion in a Romanian Population Group

TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Among a panel of polymorphisms in genes related to oxidative stress, CAT-262 C>T, GPX1 Pro198Leu and GSTP1 Ile105Val influence the risk of developing BCR-ABL negative myeloproliferative neoplasms

The relationship between factor V Leiden, prothrombin G20210A, and MTHFR mutations and the first major thrombotic episode in polycythemia vera and essential thrombocythemia

G allele of the JAK2 rs10974944 SNP, part of JAK2 46/1 haplotype, is strongly associated with JAK2 V617F-positive myeloproliferative neoplasms

The XRCC1 Arg194Trp polymorphism is significantly associated with lung adenocarcinoma: a case-control study in an Eastern European Caucasian group

Development of a reliable PCR-RFLP assay for investigation of the JAK2 rs10974944 SNP, which might predispose to the acquisition of somatic mutation JAK2(V617F)

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