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Physiological release of endogenous tau is stimulated by neuronal activity

EMBO reports, 2013-04, Vol.14 (4), p.389-394

2013

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A role for tau at the synapse in Alzheimer's disease pathogenesis

Neuropharmacology, 2014-01, Vol.76, p.1-8

2014

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Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells

Arteriosclerosis, thrombosis, and vascular biology, 2019-09, Vol.39 (9), p.e195

2019

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Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

Alzheimer's research & therapy, 2013-10, Vol.5 (5), p.49-49

2013

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Dynamic association of tau with neuronal membranes is regulated by phosphorylation

Neurobiology of aging, 2012-02, Vol.33 (2), p.431.e27-431.e38

2012

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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease

Acta neuropathologica communications, 2015-03, Vol.3 (1), p.14, Article 14

2015

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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

Neurobiology of disease, 2016-01, Vol.85, p.1-10

2016

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The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

Ageing research reviews, 2013-06, Vol.12 (3), p.757-763

2013

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Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

The EMBO journal, 2015-12, Vol.34 (24), p.3028-3041

2015

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Functional implications of the association of tau with the plasma membrane

Biochemical Society transactions, 2010-08, Vol.38 (4), p.1012

2010

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Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease

Molecular neurobiology, 2017-07, Vol.54 (5), p.3428-3438

2017

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Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

Acta neuropathologica, 2014-02, Vol.127 (2), p.257-270

2014

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Studying synapses in human brain with array tomography and electron microscopy

Nature protocols, 2013-07, Vol.8 (7), p.1366-1380

2013

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Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau

The FEBS journal, 2011-08, Vol.278 (16), p.2927-2937

2011

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Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

Cell death & disease, 2017-03, Vol.8 (3), p.e2671-e2671

2017

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Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice

Neurobiology of aging, 2016-03, Vol.39, p.1-18

2016

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Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting

The FEBS journal, 2010-12, Vol.277 (24), p.5174-5189

2010

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Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease

Acta neuropathologica communications, 2016-05, Vol.4 (1), p.49-49, Article 49

2016

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Intracellular and extracellular roles for tau in neurodegenerative disease

Journal of Alzheimer's disease, 2014, Vol.40 Suppl 1, p.S37

2014

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NUB1 modulation of GSK3β reduces tau aggregation

Human molecular genetics, 2012-12, Vol.21 (24), p.5254-5267

2012

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3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons

Journal of neurochemistry, 2006-05, Vol.97 (3), p.716-723

2006

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Advances in tau-based drug discovery

Expert opinion on drug discovery, 2011-08, Vol.6 (8), p.797-810

2011

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Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

Journal of comparative neurology (1911), 2013-12, Vol.521 (18), p.4236-4248

2013

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A systems approach to personalised nutrition: Report on the Keystone Symposium “Human Nutrition, Environment and Health”

Applied & translational genomics, 2016-09, Vol.10, p.16-18

2016

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Physiological release of endogenous tau is stimulated by neuronal activity

A role for tau at the synapse in Alzheimer's disease pathogenesis

Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells

Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

Dynamic association of tau with neuronal membranes is regulated by phosphorylation

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

Functional implications of the association of tau with the plasma membrane

Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

Studying synapses in human brain with array tomography and electron microscopy

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau

Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease

Intracellular and extracellular roles for tau in neurodegenerative disease

NUB1 modulation of GSK3β reduces tau aggregation

3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons

Advances in tau-based drug discovery

Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

A systems approach to personalised nutrition: Report on the Keystone Symposium “Human Nutrition, Environment and Health”

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