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Type II collagen degradation and its regulation in articular cartilage in osteoarthritis

Annals of the rheumatic diseases, 2002-11, Vol.61 (suppl 2), p.ii78-81

2002

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Composition and structure of articular cartilage: a template for tissue repair

Clinical orthopaedics and related research, 2001-10, Vol.391 (391 Suppl), p.S26-S33

2001

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Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

Circulation (New York, N.Y.), 1999-05, Vol.99 (19), p.2503-2509

1999

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Distinct Phases of Coordinated Early and Late Gene Expression in Growth Plate Chondrocytes in Relationship to Cell Proliferation, Matrix Assembly, Remodeling, and Cell Differentiation

Journal of bone and mineral research, 2003-05, Vol.18 (5), p.844-851

2003

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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

The Journal of clinical investigation, 2001-09, Vol.108 (6), p.817-829

2001

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Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis

Osteoarthritis and cartilage, 2011-05, Vol.19 (5), p.515-542

2011

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Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice

Human molecular genetics, 2006-06, Vol.15 (11), p.1783-1792

2006

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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

The Journal of clinical investigation, 1997-04, Vol.99 (7), p.1534-1545

1997

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Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay

The Journal of clinical investigation, 1994-04, Vol.93 (4), p.1722-1732

1994

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Serum concentrations of type II collagen biomarkers (C2C, C1, 2C and CPII) suggest different pathophysiologies in patients with hip osteoarthritis

Clinical and experimental rheumatology, 2008-05, Vol.26 (3), p.430

2008

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Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: an evaluation from 1 to 4 years after diagnosis

Arthritis research & therapy, 2006-01, Vol.8 (1), p.R31-R31

2006

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Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage

Osteoarthritis and cartilage, 2016-08, Vol.24 (8), p.1461-1469

2016

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Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis

Clinical and experimental rheumatology, 2010-07, Vol.28 (4), p.553

2010

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Type II collagen degradation in articular cartilage fibrillation after anterior cruciate ligament transection in rats

Osteoarthritis and cartilage, 2001-05, Vol.9 (4), p.308-315

2001

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Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures

Biomaterials, 1992, Vol.13 (2), p.67-97

1992

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C2K77 ELISA detects cleavage of type II collagen by cathepsin K in equine articular cartilage

Osteoarthritis and cartilage, 2017-12, Vol.25 (12), p.2119-2126

2017

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Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis : evidence for molecular heterogeneity and extensive molecular changes in disease

The Journal of clinical investigation, 1992-12, Vol.90 (6), p.2268-2277

1992

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Changes in subchondral bone in cartilage resurfacing—an experimental study in sheep using different types of osteochondral grafts

Osteoarthritis and cartilage, 2003-04, Vol.11 (4), p.265-277

2003

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Elevation of a collagenase generated type II collagen neoepitope and proteoglycan epitopes in synovial fluid following induction of joint instability in the dog

Osteoarthritis and cartilage, 2002-08, Vol.10 (8), p.662-669

2002

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An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline

Osteoarthritis and cartilage, 2000-05, Vol.8 (3), p.180-185

2000

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Relationship between pre-radiographic cartilage damage following anterior cruciate ligament injury and biomarkers of cartilage turnover in clinical practice: a cross-sectional observational study

Osteoarthritis and cartilage, 2013-06, Vol.21 (6), p.831-838

2013

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Proteoglycans in health and disease: structures and functions

Biochemical journal, 1986-05, Vol.236 (1), p.1-14

Poole, A R

1986

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Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration

Osteoarthritis and cartilage, 2004-09, Vol.12 (9), p.720-728

2004

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Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism

The Journal of clinical investigation, 1995-03, Vol.95 (3), p.1071-1077

1995

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Immunochemical markers of joint inflammation, skeletal damage and repair: where are we now?

Annals of the rheumatic diseases, 1994-01, Vol.53 (1), p.3-5

Poole, A R

1994

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Type II collagen degradation and its regulation in articular cartilage in osteoarthritis

Composition and structure of articular cartilage: a template for tissue repair

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

Distinct Phases of Coordinated Early and Late Gene Expression in Growth Plate Chondrocytes in Relationship to Cell Proliferation, Matrix Assembly, Remodeling, and Cell Differentiation

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis

Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay

Serum concentrations of type II collagen biomarkers (C2C, C1, 2C and CPII) suggest different pathophysiologies in patients with hip osteoarthritis

Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: an evaluation from 1 to 4 years after diagnosis

Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage

Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis

Type II collagen degradation in articular cartilage fibrillation after anterior cruciate ligament transection in rats

Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures

C2K77 ELISA detects cleavage of type II collagen by cathepsin K in equine articular cartilage

Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis : evidence for molecular heterogeneity and extensive molecular changes in disease

Changes in subchondral bone in cartilage resurfacing—an experimental study in sheep using different types of osteochondral grafts

Elevation of a collagenase generated type II collagen neoepitope and proteoglycan epitopes in synovial fluid following induction of joint instability in the dog

An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline

Relationship between pre-radiographic cartilage damage following anterior cruciate ligament injury and biomarkers of cartilage turnover in clinical practice: a cross-sectional observational study

Proteoglycans in health and disease: structures and functions

Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration

Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism

Immunochemical markers of joint inflammation, skeletal damage and repair: where are we now?

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