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Investigating metformin for cancer prevention and treatment: the end of the beginning

Cancer discovery, 2012-09, Vol.2 (9), p.778-790

Pollak, Michael N

2012

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Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

Biochemical journal, 2014-09, Vol.462 (3), p.475-487

2014

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Cancer, obesity, diabetes, and antidiabetic drugs: is the fog clearing?

Nature reviews. Clinical oncology, 2017-02, Vol.14 (2), p.85-99

2017

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Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial

The lancet oncology, 2015-07, Vol.16 (7), p.839-847

2015

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A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

GeroScience, 2018-12, Vol.40 (5-6), p.419-436

2018

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Metformin reduces endogenous reactive oxygen species and associated DNA damage

Cancer prevention research (Philadelphia, Pa.), 2012-04, Vol.5 (4), p.536-543

2012

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Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms

Diabetes (New York, N.Y.), 2015-05, Vol.64 (5), p.1632-1642

2015

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Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (14), p.4429-4438

2013

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Prediagnostic plasma IGFBP‐1, IGF‐1 and risk of prostate cancer

International journal of cancer, 2015-05, Vol.136 (10), p.2418-2426

2015

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The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma

Journal of bone and joint surgery. American volume, 2010-01, Vol.92 (1), p.7-15

2010

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Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3

JNCI : Journal of the National Cancer Institute, 1999-04, Vol.91 (7), p.620-625

1999

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Targeting IGF-IR improves neoadjuvant chemotherapy efficacy in breast cancers with low IGFBP7 expression

NPJ precision oncology, 2024-10, Vol.8 (1), p.212-11, Article 212

2024

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The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase

Cancer prevention research (Philadelphia, Pa.), 2008-10, Vol.1 (5), p.369-375

2008

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Cancer Immunoprevention: A Case Report Raising the Possibility of "Immuno-interception"

Cancer prevention research (Philadelphia, Pa.), 2020-04, Vol.13 (4), p.351-356

2020

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Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

Cell reports (Cambridge), 2018-07, Vol.24 (1), p.47-55

2018

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In vitro metformin anti-neoplastic activity in epithelial ovarian cancer

Gynecologic oncology, 2008-08, Vol.110 (2), p.246-250

2008

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Insulin-like growth factors and neoplasia

Nature reviews. Cancer, 2004-07, Vol.4 (7), p.505-518

2004

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Outer membrane vesicles from Brucella abortus promote bacterial internalization by human monocytes and modulate their innate immune response

PloS one, 2012-11, Vol.7 (11), p.e50214-e50214

2012

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Insulin, the Insulin-Like Growth Factor Axis, and Mortality in Patients With Nonmetastatic Colorectal Cancer

Journal of clinical oncology, 2009-01, Vol.27 (2), p.176-185

2009

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The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study

BMJ (Online), 2012-05, Vol.344 (may30 3), p.e3645-e3645

2012

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Gene and protein expression and metabolic flux analysis reveals metabolic scaling in liver ex vivo and in vivo

eLife, 2023-05, Vol.12

2023

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A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts

JNCI : Journal of the National Cancer Institute, 2013-01, Vol.105 (2), p.95-103

2013

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On the relationship between cell cycle analysis with ergodic principles and age-structured cell population models

Journal of theoretical biology, 2017-02, Vol.414, p.91-102

2017

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Obesity, Diabetes, and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial

Cancer epidemiology, biomarkers & prevention, 2006-10, Vol.15 (10), p.1977-1983

2006

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Are injured workers with higher rehabilitation service utilization less likely to be persistent opioid users? A cross-sectional study

BMC health services research, 2019-01, Vol.19 (1), p.32-32, Article 32

2019

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Investigating metformin for cancer prevention and treatment: the end of the beginning

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

Cancer, obesity, diabetes, and antidiabetic drugs: is the fog clearing?

Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

Metformin reduces endogenous reactive oxygen species and associated DNA damage

Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms

Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism

Prediagnostic plasma IGFBP‐1, IGF‐1 and risk of prostate cancer

The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3

Targeting IGF-IR improves neoadjuvant chemotherapy efficacy in breast cancers with low IGFBP7 expression

The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase

Cancer Immunoprevention: A Case Report Raising the Possibility of "Immuno-interception"

Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

In vitro metformin anti-neoplastic activity in epithelial ovarian cancer

Insulin-like growth factors and neoplasia

Outer membrane vesicles from Brucella abortus promote bacterial internalization by human monocytes and modulate their innate immune response

Insulin, the Insulin-Like Growth Factor Axis, and Mortality in Patients With Nonmetastatic Colorectal Cancer

The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study

Gene and protein expression and metabolic flux analysis reveals metabolic scaling in liver ex vivo and in vivo

A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts

On the relationship between cell cycle analysis with ergodic principles and age-structured cell population models

Obesity, Diabetes, and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial

Are injured workers with higher rehabilitation service utilization less likely to be persistent opioid users? A cross-sectional study

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