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Wnt signaling and cancer

Genes & development, 2000-08, Vol.14 (15), p.1837-1851

Polakis, P

2000

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Wnt signaling in cancer

Cold Spring Harbor perspectives in biology, 2012-05, Vol.4 (5), p.a008052-a008052

Polakis, Paul

2012

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Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

Oncogene, 2006-07, Vol.25 (31), p.4361-4369

2006

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Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

Oncogene, 2006-07, Vol.25 (31), p.4361-4369

2006

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The oncogenic activation of β-catenin

Current opinion in genetics & development, 1999-02, Vol.9 (1), p.15-21

Polakis, Paul

1999

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The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell

Current biology, 1999-02, Vol.9 (4), p.207-211

1999

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Regulation of Intracellular β-Catenin Levels by the Adenomatous Polyposis Coli (APC) Tumor-Suppressor Protein

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (7), p.3046-3050

1995

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Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

Molecular and Cellular Biology, 1996-05, Vol.16 (5), p.2128-2134

1996

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Casein Kinase 1: A Wnt'er of Disconnect

Current biology, 2002-07, Vol.12 (14), p.R499-R501

Polakis, Paul

2002

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IQGAP1, a calmodulin‐binding protein with a rasGAP‐related domain, is a potential effector for cdc42Hs

The EMBO journal, 1996-06, Vol.15 (12), p.2997-3005

1996

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The Adenomatous Polyposis Coli Tumor Suppressor Protein Localizes to Plasma Membrane Sites Involved in Active Cell Migration

The Journal of cell biology, 1996-07, Vol.134 (1), p.165-179

1996

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Arming antibodies for cancer therapy

Current opinion in pharmacology, 2005-08, Vol.5 (4), p.382-387

Polakis, Paul

2005

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Wnt Signaling in Oncogenesis and Embryogenesis-A Look outside the Nucleus

Science (American Association for the Advancement of Science), 2000-03, Vol.287 (5458), p.1606-1609

2000

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Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9157-9160

1993

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The adenomatous polyposis coli (APC) tumor suppressor

Biochimica et biophysica acta, 1997-06, Vol.1332 (3), p.F127-F147

Polakis, Paul

1997

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More Than One Way to Skin a Catenin

Cell, 2001-06, Vol.105 (5), p.563-566

Polakis, Paul

2001

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Mutations in the APC gene and their implications for protein structure and function

Current opinion in genetics & development, 1995-01, Vol.5 (1), p.66-71

Polakis, Paul

1995

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Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

Molecular and Cellular Biology, 1991-04, Vol.11 (4), p.1804-1812

1991

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Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

Science (American Association for the Advancement of Science), 1996-05, Vol.272 (5264), p.1023-1026

1996

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Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β

Current biology, 1998-05, Vol.8 (10), p.573-581

1998

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Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

Science (American Association for the Advancement of Science), 1997-03, Vol.275 (5307), p.1790-1792

1997

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Purification of a Plasma Membrane-Associated GTPase-Activating Protein Specific for Rap1/Krev-1 from HL60 Cells

Proceedings of the National Academy of Sciences - PNAS, 1991-01, Vol.88 (1), p.239-243

1991

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ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K + channels

Cell, 1990-06, Vol.61 (5), p.769-776

1990

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1598PTRANSLATIONAL PKPD OF DNIB0600A, AN ANTI-NAPI2B-VC-MMAE ADC IN OVARIAN AND NSCLC CANCERS

Annals of oncology, 2014-09, Vol.25 (suppl_4), p.iv554-iv554

2014

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Translational Pkpd of Dnib0600A, an Anti-Napi2B-Vc-Mmae Adc in Ovarian and Nsclc Cancers

Annals of oncology, 2014-09, Vol.25, p.iv554

2014

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Wnt signaling and cancer

Wnt signaling in cancer

Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

The oncogenic activation of β-catenin

The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell

Regulation of Intracellular β-Catenin Levels by the Adenomatous Polyposis Coli (APC) Tumor-Suppressor Protein

Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

Casein Kinase 1: A Wnt'er of Disconnect

IQGAP1, a calmodulin‐binding protein with a rasGAP‐related domain, is a potential effector for cdc42Hs

The Adenomatous Polyposis Coli Tumor Suppressor Protein Localizes to Plasma Membrane Sites Involved in Active Cell Migration

Arming antibodies for cancer therapy

Wnt Signaling in Oncogenesis and Embryogenesis-A Look outside the Nucleus

Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target

The adenomatous polyposis coli (APC) tumor suppressor

More Than One Way to Skin a Catenin

Mutations in the APC gene and their implications for protein structure and function

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β

Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

Purification of a Plasma Membrane-Associated GTPase-Activating Protein Specific for Rap1/Krev-1 from HL60 Cells

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K + channels

1598PTRANSLATIONAL PKPD OF DNIB0600A, AN ANTI-NAPI2B-VC-MMAE ADC IN OVARIAN AND NSCLC CANCERS

Translational Pkpd of Dnib0600A, an Anti-Napi2B-Vc-Mmae Adc in Ovarian and Nsclc Cancers

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