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Human papillomavirus type 16 E6 induces cell competition

PLoS pathogens, 2022-03, Vol.18 (3), p.e1010431-e1010431

2022

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Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Nature (London), 2016-01, Vol.529 (7587), p.541-545

2016

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Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness

PLoS pathogens, 2017-12, Vol.13 (12), p.e1006781-e1006781

2017

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Multiple regions of E6AP (UBE3A) contribute to interaction with papillomavirus E6 proteins and the activation of ubiquitin ligase activity

PLoS pathogens, 2020-01, Vol.16 (1), p.e1008295-e1008295

2020

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Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

Science (American Association for the Advancement of Science), 2013-02, Vol.339 (6120), p.694-698

2013

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Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems

PLoS pathogens, 2015-10, Vol.11 (10), p.e1005138-e1005138

2015

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E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007575-e1007575

2019

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Papillomavirus E6 PDZ Interactions Can Be Replaced by Repression of p53 To Promote Episomal Human Papillomavirus Genome Maintenance

Journal of Virology, 2014-03, Vol.88 (5), p.3027-3030

2014

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Papillomavirus E6 oncoproteins

Virology (New York, N.Y.), 2013-10, Vol.445 (1), p.115-137

2013

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Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes

The Journal of cell biology, 2016-06, Vol.213 (5), p.585-599

2016

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The Stardust Family Protein MPP7 Forms a Tripartite Complex with LIN7 and DLG1 That Regulates the Stability and Localization of DLG1 to Cell Junctions

The Journal of biological chemistry, 2007-03, Vol.282 (13), p.9392-9400

2007

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E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/[beta]-catenin pathway through E6AP-dependent degradation of NHERF1

PLoS pathogens, 2019-04, Vol.15 (4)

2019

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Degradation of Tyrosine Phosphatase PTPN3 (PTPH1) by Association with Oncogenic Human Papillomavirus E6 Proteins

Journal of Virology, 2007-03, Vol.81 (5), p.2231-2239

2007

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The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC

Journal of virology, 2016-06, Vol.90 (12), p.5611-5621

2016

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Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization

Virology (New York, N.Y.), 2018-03, Vol.516, p.127-138

2018

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Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein

Virology (New York, N.Y.), 2007-02, Vol.358 (2), p.303-310

2007

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Transformation by Bovine Papillomavirus Type 1 E6 Requires Paxillin

Journal of Virology, 2008-06, Vol.82 (12), p.5962-5966

2008

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Paxillin contracts the osteoclast cytoskeleton

Journal of bone and mineral research, 2012-12, Vol.27 (12), p.2490-2500

2012

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Destabilization of TIP60 by Human Papillomavirus E6 Results in Attenuation of TIP60-Dependent Transcriptional Regulation and Apoptotic Pathway

Molecular cell, 2010-06, Vol.38 (5), p.700-711

2010

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Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6

Journal of virology, 2014-09, Vol.88 (17), p.9927-9933

2014

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Human Papillomavirus E6 Regulates the Cytoskeleton Dynamics of Keratinocytes through Targeted Degradation of p53

Journal of Virology, 2007-11, Vol.81 (22), p.12675-12679

2007

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Requirement of e6ap and the features of human papillomavirus e6 necessary to support degradation of p53

Virology (New York, N.Y.), 2003-02, Vol.306 (1), p.87-99

2003

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PAT1, a Microtubule-Interacting Protein, Recognizes the Basolateral Sorting Signal of Amyloid Precursor Protein

Proceedings of the National Academy of Sciences - PNAS, 1998-12, Vol.95 (25), p.14745-14750

1998

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HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002807

2012

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Paxillin Enables Attachment-independent Tyrosine Phosphorylation of Focal Adhesion Kinase and Transformation by RAS

The Journal of biological chemistry, 2011-11, Vol.286 (44), p.37932-37944

2011

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Human papillomavirus type 16 E6 induces cell competition

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness

Multiple regions of E6AP (UBE3A) contribute to interaction with papillomavirus E6 proteins and the activation of ubiquitin ligase activity

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems

E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1

Papillomavirus E6 PDZ Interactions Can Be Replaced by Repression of p53 To Promote Episomal Human Papillomavirus Genome Maintenance

Papillomavirus E6 oncoproteins

Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes

The Stardust Family Protein MPP7 Forms a Tripartite Complex with LIN7 and DLG1 That Regulates the Stability and Localization of DLG1 to Cell Junctions

E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/[beta]-catenin pathway through E6AP-dependent degradation of NHERF1

Degradation of Tyrosine Phosphatase PTPN3 (PTPH1) by Association with Oncogenic Human Papillomavirus E6 Proteins

The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC

Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization

Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein

Transformation by Bovine Papillomavirus Type 1 E6 Requires Paxillin

Paxillin contracts the osteoclast cytoskeleton

Destabilization of TIP60 by Human Papillomavirus E6 Results in Attenuation of TIP60-Dependent Transcriptional Regulation and Apoptotic Pathway

Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6

Human Papillomavirus E6 Regulates the Cytoskeleton Dynamics of Keratinocytes through Targeted Degradation of p53

Requirement of e6ap and the features of human papillomavirus e6 necessary to support degradation of p53

PAT1, a Microtubule-Interacting Protein, Recognizes the Basolateral Sorting Signal of Amyloid Precursor Protein

HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage

Paxillin Enables Attachment-independent Tyrosine Phosphorylation of Focal Adhesion Kinase and Transformation by RAS

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