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The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity

Journal of medicinal chemistry, 2015-03, Vol.58 (6), p.2855-2861

2015

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Structural basis for the fast maturation of Arthropoda green fluorescent protein

EMBO reports, 2006-10, Vol.7 (10), p.1006-1012

2006

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1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1574-1578

2006

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Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO 4) as the active component

Journal of inorganic biochemistry, 2003-08, Vol.96 (2), p.321-330

2003

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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Journal of medicinal chemistry, 2001-03, Vol.44 (7), p.1060-1071

2001

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Design and synthesis of potent, non-peptidic inhibitors of HPTPβ

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4252-4256

2006

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Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2‑Associated Kinase 1 Inhibitors

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.4121-4155

2022

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The high-mosaicity illusion: revealing the true physical characteristics of macromolecular crystals

Acta crystallographica. Section D, Biological crystallography., 2000-08, Vol.56 (8), p.986-995

2000

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Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage

ACS medicinal chemistry letters, 2020-03, Vol.11 (3), p.266-271

2020

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Design and synthesis of a series of novel pyrazolopyridines as HIF 1-α prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5687-5690

2006

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A novel series of imidazo[1,2- a]pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5598-5601

2006

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Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

Journal of medicinal chemistry, 2008-01, Vol.51 (1), p.4-16

2008

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Similar modes of polypeptide recognition by export chaperones in flagellar biosynthesis and type III secretion

Nature structural & molecular biology, 2003-10, Vol.10 (10), p.789-793

2003

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Dynamically Optimizing Experiment Schedules of a Laboratory Robot System with Simulated Annealing

Journal of Laboratory Automation, 2014-12, Vol.19 (6), p.517-527

2014

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Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5517-5522

2006

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Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase 1 1Edited by R. Huber

Journal of molecular biology, 2000-03, Vol.296 (4), p.951-959

2000

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Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5659-5663

2006

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Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase

Journal of molecular biology, 2000-03, Vol.296 (4), p.951-959

2000

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Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5616-5620

2006

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Development of New Hydroxamate Matrix Metalloproteinase Inhibitors Derived from Functionalized 4-Aminoprolines

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.4948-4963

2000

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Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors

Proteins, structure, function, and bioinformatics, 2007-02, Vol.66 (3), p.538-546

2007

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Corrigendum to “Design and synthesis of potent, non-peptidic inhibitors of HPTPβ” [Bioorg. Med. Chem. Lett. 16 (2006) 4252–4256]

Bioorganic & medicinal chemistry letters, 2008-08, Vol.18 (16), p.4745-4745

2008

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A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5598-5601

2006

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Design and synthesis of a series of novel pyrazolopyridines as HIF-1alpha prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5687-5690

2006

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Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5517-5522

2006

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The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity

Structural basis for the fast maturation of Arthropoda green fluorescent protein

1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO 4) as the active component

Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Design and synthesis of potent, non-peptidic inhibitors of HPTPβ

Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2‑Associated Kinase 1 Inhibitors

The high-mosaicity illusion: revealing the true physical characteristics of macromolecular crystals

Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage

Design and synthesis of a series of novel pyrazolopyridines as HIF 1-α prolyl hydroxylase inhibitors

A novel series of imidazo[1,2- a]pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

Similar modes of polypeptide recognition by export chaperones in flagellar biosynthesis and type III secretion

Dynamically Optimizing Experiment Schedules of a Laboratory Robot System with Simulated Annealing

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors

Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase 1 1Edited by R. Huber

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase

Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Development of New Hydroxamate Matrix Metalloproteinase Inhibitors Derived from Functionalized 4-Aminoprolines

Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors

Corrigendum to “Design and synthesis of potent, non-peptidic inhibitors of HPTPβ” [Bioorg. Med. Chem. Lett. 16 (2006) 4252–4256]

A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors

Design and synthesis of a series of novel pyrazolopyridines as HIF-1alpha prolyl hydroxylase inhibitors

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors

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