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4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (R/S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors: Design, Synthesis, Pharmacology, and Structure−Activity Relationships

Journal of medicinal chemistry, 1998-07, Vol.41 (16), p.2946-2959

1998

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Circumvention of P-GP MDR as a Function of Anthracycline Lipophilicity and Charge

Biochemistry (Easton), 1997-03, Vol.36 (9), p.2679-2685

1997

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3- and 4-Substituted 4H-Pyrido[4,3-e]-1,2,4-thiadiazine 1,1-Dioxides as Potassium Channel Openers: Synthesis, Pharmacological Evaluation, and Structure−Activity Relationships

Journal of medicinal chemistry, 1996-02, Vol.39 (4), p.937-948

1996

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Pyridothiadiazinedioxides structurally related to quinazolinones cholecystokinin/gastrin receptor ligands: synthesis and biological evaluation

European journal of pharmaceutical sciences, 1998-12, Vol.7 (1), p.29-40

1998

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4-Ethyl-2,3-dihydro-4H-pyrido[3,2-e]-1,2,4-thiadiazine 1,1-dioxide and 4-ethyl-2,3-dihydro-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide

Acta crystallographica. Section C, Crystal structure communications, 1999-03, Vol.55 (3), p.461-464

1999

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Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans : new synthesis and dopaminergic activity

European journal of medicinal chemistry, 1991-07, Vol.26 (5), p.497-504

1991

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3-Amino-3,4-dihydro-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. 2. Synthesis and Quantitative Structure−Activity Relationship Studies of Spiro[pyrrolidine- and piperidine-2,3‘(2‘H)-benzopyrans]

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4285-4298

1996

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3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies

Journal of medicinal chemistry, 1994-06, Vol.37 (12), p.1779-1793

1994

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Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

Tetrahedron, 1995-03, Vol.51 (11), p.3221-3234

1995

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Comparison of annamycin to adriamycin in cardiac and MDR tumor cell systems

Anticancer research, 1999-03, Vol.19 (2A), p.1277

1999

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4H-1,2,4-pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2,4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propio acid receptors : Design, synthesis, pharmacology, and structure-activity relationships

Journal of medicinal chemistry, 1998, Vol.41 (16), p.2946-2959

1998

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4-Ethyl-2,3-dihydro-4 H -pyrido[3,2- e ]-1,2,4-thiadiazine 1,1-dioxide and 4-ethyl-2,3-dihydro-4 H -pyrido[4,3- e ]-1,2,4-thiadiazine 1,1-dioxide

Acta crystallographica. Section C, Crystal structure communications, 1999-03, Vol.55 (3), p.461-464

1999

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Synthèse de N-(2-hydroxyéthyl)iminoglutarimides à partir de N-(2-bromoéthyl)glutarimides

Tetrahedron, 1993-05, Vol.49 (21), p.4619-4626

1993

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Synthesis and Biological Evaluation of New 3-Aralkylamino-2-aryl-2H-1,2,4-pyridothiadiazine 1,1-dioxides as Potential CCK-Receptor Ligands

Journal of pharmacy and pharmacology, 1997-05, Vol.49 (5), p.463-471

1997

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3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. I: Synthesis and structure-activity relationship studies

Journal of medicinal chemistry, 1994, Vol.37 (12), p.1779-1793

1994

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3-Amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT sub(1A) receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans]

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4285-4298

1996

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Fluorescent probes for 5-HT1A receptors: synthesis and characterization of 5-methoxy-3-[n-propyl-(4-n-aminobutyl)] amino-3,4-dihydro-2H-1-benzopyran derivatives

Bioorganic & medicinal chemistry letters, 1993-10, Vol.3 (10), p.1935-1940

1993

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3- and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers : synthesis, pharmacological evaluation, and structure-activity relationships

Journal of medicinal chemistry, 1995, Vol.39 (4), p.937-948

1995

Volltextzugriff (PDF)

Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di- n-propylamino)-2 H-1-benzopyrans: new synthesis and dopaminergic activity

European journal of medicinal chemistry, 1991, Vol.26 (5), p.497-504

1991

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Brevetoxin derivatives that inhibit toxin activity

Chemistry & biology, 2000-06, Vol.7 (6), p.385-393

2000

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ChemInform Abstract: Synthesis of N-(2-Hydroxyethyl)iminoglutarimides from N-(2-Bromoethyl) glutarimides

ChemInform, 1993-10, Vol.24 (41), p.no-no

1993

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Pyrido- and benzothiadiazine dioxides related to diazoxide: structural requirements leading to a KATP channel activator or to an allosteric modulator of the AMPA receptors

1999

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ChemInform Abstract: Synthesis and Structural Studies of a New Class of Heterocyclic Compounds: 1,2,4-Pyridothiadiazine 1,1-Dioxides, Pyridyl Analogues of 1,2,4-Benzothiadiazine 1,1-Dioxides

ChemInform, 1995-08, Vol.26 (33), p.no-no

1995

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ChemInform Abstract: 3,4-Dihydro-3-amino-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. Part 1. Synthesis and Structure-Activity Relationship Studies

ChemInform, 1994-11, Vol.25 (44), p.no-no

1994

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Synthesis ans structural studies of a new class of heterocyclic compounds: 1,2,4-pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

1995

Volltextzugriff (PDF)

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Circumvention of P-GP MDR as a Function of Anthracycline Lipophilicity and Charge

3- and 4-Substituted 4H-Pyrido[4,3-e]-1,2,4-thiadiazine 1,1-Dioxides as Potassium Channel Openers: Synthesis, Pharmacological Evaluation, and Structure−Activity Relationships

Pyridothiadiazinedioxides structurally related to quinazolinones cholecystokinin/gastrin receptor ligands: synthesis and biological evaluation

4-Ethyl-2,3-dihydro-4H-pyrido[3,2-e]-1,2,4-thiadiazine 1,1-dioxide and 4-ethyl-2,3-dihydro-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide

Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans : new synthesis and dopaminergic activity

3-Amino-3,4-dihydro-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. 2. Synthesis and Quantitative Structure−Activity Relationship Studies of Spiro[pyrrolidine- and piperidine-2,3‘(2‘H)-benzopyrans]

3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies

Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

Comparison of annamycin to adriamycin in cardiac and MDR tumor cell systems

4-Ethyl-2,3-dihydro-4 H -pyrido[3,2- e ]-1,2,4-thiadiazine 1,1-dioxide and 4-ethyl-2,3-dihydro-4 H -pyrido[4,3- e ]-1,2,4-thiadiazine 1,1-dioxide

Synthèse de N-(2-hydroxyéthyl)iminoglutarimides à partir de N-(2-bromoéthyl)glutarimides

Synthesis and Biological Evaluation of New 3-Aralkylamino-2-aryl-2H-1,2,4-pyridothiadiazine 1,1-dioxides as Potential CCK-Receptor Ligands

3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. I: Synthesis and structure-activity relationship studies

3-Amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT sub(1A) receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans]

Fluorescent probes for 5-HT1A receptors: synthesis and characterization of 5-methoxy-3-[n-propyl-(4-n-aminobutyl)] amino-3,4-dihydro-2H-1-benzopyran derivatives

3- and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers : synthesis, pharmacological evaluation, and structure-activity relationships

Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di- n-propylamino)-2 H-1-benzopyrans: new synthesis and dopaminergic activity

Brevetoxin derivatives that inhibit toxin activity

ChemInform Abstract: Synthesis of N-(2-Hydroxyethyl)iminoglutarimides from N-(2-Bromoethyl) glutarimides

Pyrido- and benzothiadiazine dioxides related to diazoxide: structural requirements leading to a KATP channel activator or to an allosteric modulator of the AMPA receptors

ChemInform Abstract: Synthesis and Structural Studies of a New Class of Heterocyclic Compounds: 1,2,4-Pyridothiadiazine 1,1-Dioxides, Pyridyl Analogues of 1,2,4-Benzothiadiazine 1,1-Dioxides

ChemInform Abstract: 3,4-Dihydro-3-amino-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. Part 1. Synthesis and Structure-Activity Relationship Studies

Synthesis ans structural studies of a new class of heterocyclic compounds: 1,2,4-pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

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