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Modeling of Human Dermal Absorption of Octamethylcyclotetrasiloxane (D4) and Decamethylcyclopentasiloxane (D5)

Toxicological sciences, 2007-10, Vol.99 (2), p.422-431

2007

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A 28-day whole-body inhalation study to evaluate octamethylcyclotetrasiloxane (D4) absorption/distribution in two rat strains

Toxicology letters, 2022-11, Vol.370, p.53-65

2022

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Chronic toxicity and oncogenicity of octamethylcyclotetrasiloxane (D4) in the Fischer 344 rat

Toxicology letters, 2017-10, Vol.279, p.75-97

2017

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Comparative pharmacokinetic studies of 14C-octamethylcyclotetrasiloxane (14C-D4) in Fischer 344 and Sprague Dawley CD rats after single and repeated inhalation exposure

Toxicology letters, 2023-01, Vol.373, p.13-21

2023

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Effects of chronic exposure to octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane in the aging female Fischer 344 rat

Toxicology letters, 2017-10, Vol.279, p.54-74

2017

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A two-generation reproductive toxicity study of octamethylcyclotetrasiloxane (D 4) in rats exposed by whole-body vapor inhalation

Reproductive toxicology (Elmsford, N.Y.), 2007-02, Vol.23 (2), p.202-215

2007

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An inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D 4) in female rats using multiple and single day exposure regimens

Reproductive toxicology (Elmsford, N.Y.), 2007-02, Vol.23 (2), p.192-201

2007

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Chronic toxicity and oncogenicity of decamethylcyclopentasiloxane in the Fischer 344 Rat

Regulatory toxicology and pharmacology, 2016-02, Vol.74, p.S57-S66

2016

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Metabolism and disposition of [14C]-methylcyclosiloxanes in rats

Toxicology letters, 2017-10, Vol.279, p.98-114

2017

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In Vitro and In Vivo Evaluation of the Estrogenic, Androgenic, and Progestagenic Potential of Two Cyclic Siloxanes

Toxicological sciences, 2007-03, Vol.96 (1), p.145-153

2007

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Are highly lipophilic volatile compounds expected to bioaccumulate with repeated exposures?

Toxicology letters, 2008-06, Vol.179 (2), p.85-92

2008

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Effects of octamethylcyclotetrasiloxane (D 4) on the luteinizing hormone (LH) surge and levels of various reproductive hormones in female Sprague–Dawley rats

Reproductive toxicology (Elmsford, N.Y.), 2007-06, Vol.23 (4), p.532-540

2007

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In vitro and In vivo percutaneous absorption of 14C-octamethylcyclotetrasiloxane ( 14C-D 4) and 14C-decamethylcyclopentasiloxane ( 14C-D 5)

Regulatory toxicology and pharmacology, 2008-03, Vol.50 (2), p.239-248

2008

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Inhalation Dosimetry Modeling with Decamethylcyclopentasiloxane in Rats and Humans

Toxicological sciences, 2008-10, Vol.105 (2), p.275-285

2008

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Disposition of Decamethylcyclopentasiloxane in Fischer 344 Rats Following Single or Repeated Inhalation Exposure to 14C-Decamethylcyclopentasiloxane (14C-D5)

Inhalation toxicology, 2008-03, Vol.20 (5), p.513-531

2008

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Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine--a comparison of a linear and a cyclic siloxane

Drug metabolism and disposition, 2003-02, Vol.31 (2), p.206-214

2003

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Physiological Modeling of Inhalation Kinetics of Octamethylcyclotetrasiloxane in Humans during Rest and Exercise

Toxicological sciences, 2003-03, Vol.72 (1), p.3-18

2003

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Route-Specific Differences in Distribution Characteristics of Octamethylcyclotetrasiloxane in Rats: Analysis Using PBPK Models

Toxicological sciences, 2003-01, Vol.71 (1), p.41-52

2003

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A two-generation reproductive toxicity study of decamethylcyclopentasiloxane (D 5) in rats exposed by whole-body vapor inhalation

Reproductive toxicology (Elmsford, N.Y.), 2007-02, Vol.23 (2), p.216-225

2007

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Physiological Modeling Reveals Novel Pharmacokinetic Behavior for Inhaled Octamethylcyclotetrasiloxane in Rats

Toxicological sciences, 2001-04, Vol.60 (2), p.214-231

2001

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Assessing Kinetic Determinants for Metabolism and Oral Uptake of Octamethylcyclotetrasiloxane (D4) from Inhalation Chamber Studies

Inhalation toxicology, 2008-01, Vol.20 (4), p.361-373

2008

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Identification of metabolites of octamethylcyclotetrasiloxane (D(4)) in rat urine

Drug metabolism and disposition, 1999-11, Vol.27 (11), p.1267

1999

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Dose-Response Modeling of Cytochrome P450 Induction in Rats by Octamethylcyclotetrasiloxane

Toxicological sciences, 2002-06, Vol.67 (2), p.159-172

2002

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Comparative pharmacokinetic studies of 14 C-octamethylcyclotetrasiloxane ( 14 C-D4) in Fischer 344 and Sprague Dawley CD rats after single and repeated inhalation exposure

Toxicology letters, 2023-01, Vol.373, p.13

2023

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Extraction of Octamethylcyclotetrasiloxane and Its Metabolites from Biological Matrices

Analytical biochemistry, 1998-02, Vol.256 (1), p.14-22

1998

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Modeling of Human Dermal Absorption of Octamethylcyclotetrasiloxane (D4) and Decamethylcyclopentasiloxane (D5)

A 28-day whole-body inhalation study to evaluate octamethylcyclotetrasiloxane (D4) absorption/distribution in two rat strains

Chronic toxicity and oncogenicity of octamethylcyclotetrasiloxane (D4) in the Fischer 344 rat

Comparative pharmacokinetic studies of 14C-octamethylcyclotetrasiloxane (14C-D4) in Fischer 344 and Sprague Dawley CD rats after single and repeated inhalation exposure

Effects of chronic exposure to octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane in the aging female Fischer 344 rat

A two-generation reproductive toxicity study of octamethylcyclotetrasiloxane (D 4) in rats exposed by whole-body vapor inhalation

An inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D 4) in female rats using multiple and single day exposure regimens

Chronic toxicity and oncogenicity of decamethylcyclopentasiloxane in the Fischer 344 Rat

Metabolism and disposition of [14C]-methylcyclosiloxanes in rats

In Vitro and In Vivo Evaluation of the Estrogenic, Androgenic, and Progestagenic Potential of Two Cyclic Siloxanes

Are highly lipophilic volatile compounds expected to bioaccumulate with repeated exposures?

Effects of octamethylcyclotetrasiloxane (D 4) on the luteinizing hormone (LH) surge and levels of various reproductive hormones in female Sprague–Dawley rats

In vitro and In vivo percutaneous absorption of 14C-octamethylcyclotetrasiloxane ( 14C-D 4) and 14C-decamethylcyclopentasiloxane ( 14C-D 5)

Inhalation Dosimetry Modeling with Decamethylcyclopentasiloxane in Rats and Humans

Disposition of Decamethylcyclopentasiloxane in Fischer 344 Rats Following Single or Repeated Inhalation Exposure to 14C-Decamethylcyclopentasiloxane (14C-D5)

Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine--a comparison of a linear and a cyclic siloxane

Physiological Modeling of Inhalation Kinetics of Octamethylcyclotetrasiloxane in Humans during Rest and Exercise

Route-Specific Differences in Distribution Characteristics of Octamethylcyclotetrasiloxane in Rats: Analysis Using PBPK Models

A two-generation reproductive toxicity study of decamethylcyclopentasiloxane (D 5) in rats exposed by whole-body vapor inhalation

Physiological Modeling Reveals Novel Pharmacokinetic Behavior for Inhaled Octamethylcyclotetrasiloxane in Rats

Assessing Kinetic Determinants for Metabolism and Oral Uptake of Octamethylcyclotetrasiloxane (D4) from Inhalation Chamber Studies

Identification of metabolites of octamethylcyclotetrasiloxane (D(4)) in rat urine

Dose-Response Modeling of Cytochrome P450 Induction in Rats by Octamethylcyclotetrasiloxane

Comparative pharmacokinetic studies of 14 C-octamethylcyclotetrasiloxane ( 14 C-D4) in Fischer 344 and Sprague Dawley CD rats after single and repeated inhalation exposure

Extraction of Octamethylcyclotetrasiloxane and Its Metabolites from Biological Matrices

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