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Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition

PloS one, 2015-06, Vol.10 (6), p.e0130518-e0130518

2015

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Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (23), p.11061-11070

2005

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An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

Molecular therapy. Oncolytics, 2016, Vol.3 (C), p.1-9, Article 16023

2016

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Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

Science translational medicine, 2014-11, Vol.6 (261), p.261ra151

2014

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Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

Cancer cell, 2015-10, Vol.28 (4), p.415-428

2015

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Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus

The Journal of immunology (1950), 2003-11, Vol.171 (9), p.4521-4527

2003

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207. Optimal Activation of Both CD28 and 4-1BB in CAR-Targeted T Cells Results in Enhanced Tumor Eradication

Molecular therapy, 2015-05, Vol.23, p.S82-S82

2015

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Retrovirally expressed 4-1BBL dramatically increases proliferation and in vivo persistence of adoptively transferred CD19-targeted T cells, promoting complete tumor elimination. (131.16)

The Journal of immunology (1950), 2010-04, Vol.184 (1_Supplement), p.131-131.16

2010

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Analysis of Transcription Factor Expression during Discrete Stages of Postnatal Thymocyte Differentiation

The Journal of immunology (1950), 2004-07, Vol.173 (2), p.1094-1102

2004

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Artificial Antigen Presenting Cells Expand NY-ESO-1 Antigen-Specific CD8+ T Cells From Patients with Melanoma

Blood, 2011-11, Vol.118 (21), p.4309-4309

2011

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Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication

Molecular therapy, 2010-02, Vol.18 (2), p.413-420

2010

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Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition: e0130518

PloS one, 2015-06, Vol.10 (6)

2015

Volltextzugriff (PDF)

Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

Endocrinology (Philadelphia), 2017-03, Vol.158 (3), p.664-677

2017

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The effects of resistance training to near failure on strength, hypertrophy, and motor unit adaptations in previously trained adults

Physiological reports, 2023-05, Vol.11 (9), p.e15679-n/a

2023

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Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

Nature communications, 2018-10, Vol.9 (1), p.4406-13, Article 4406

2018

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Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

Neurology, 2012-08, Vol.79 (9), p.897

2012

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New York City COVID-19 resident physician exposure during exponential phase of pandemic

The Journal of clinical investigation, 2020-09, Vol.130 (9), p.4726-4733

2020

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Increased condom use among key populations using oral PrEP in Kenya: results from large scale programmatic surveillance

BMC public health, 2022-02, Vol.22 (1), p.304-304, Article 304

2022

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Estimating prevalence of human traits among populations from polygenic risk scores

Human genomics, 2021-12, Vol.15 (1), p.70-70, Article 70

2021

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On the accessibility of adaptive phenotypes of a bacterial metabolic network

PLoS computational biology, 2009-08, Vol.5 (8), p.e1000472-e1000472

2009

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Novel CSF biomarkers for Alzheimer’s disease and mild cognitive impairment

Acta neuropathologica, 2010-06, Vol.119 (6), p.669-678

2010

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A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

Alzheimer's & dementia, 2014-07, Vol.10 (4), p.477-484.e1

2014

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Using discrete choice experiments to inform the design of complex interventions

Trials, 2019-03, Vol.20 (1), p.157-157, Article 157

2019

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The science of vaccine safety: Summary of meeting at Wellcome Trust

Vaccine, 2020-02, Vol.38 (8), p.1869-1880

2020

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White Paper on studying the safety of the childhood immunization schedule in the Vaccine Safety Datalink

Vaccine, 2016-02, Vol.34, p.A1-A29

2016

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Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition

Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus

207. Optimal Activation of Both CD28 and 4-1BB in CAR-Targeted T Cells Results in Enhanced Tumor Eradication

Retrovirally expressed 4-1BBL dramatically increases proliferation and in vivo persistence of adoptively transferred CD19-targeted T cells, promoting complete tumor elimination. (131.16)

Analysis of Transcription Factor Expression during Discrete Stages of Postnatal Thymocyte Differentiation

Artificial Antigen Presenting Cells Expand NY-ESO-1 Antigen-Specific CD8+ T Cells From Patients with Melanoma

Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication

Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition: e0130518

Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

The effects of resistance training to near failure on strength, hypertrophy, and motor unit adaptations in previously trained adults

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

New York City COVID-19 resident physician exposure during exponential phase of pandemic

Increased condom use among key populations using oral PrEP in Kenya: results from large scale programmatic surveillance

Estimating prevalence of human traits among populations from polygenic risk scores

On the accessibility of adaptive phenotypes of a bacterial metabolic network

Novel CSF biomarkers for Alzheimer’s disease and mild cognitive impairment

A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

Using discrete choice experiments to inform the design of complex interventions

The science of vaccine safety: Summary of meeting at Wellcome Trust

White Paper on studying the safety of the childhood immunization schedule in the Vaccine Safety Datalink

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