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Polymeric drugs based on conjugates of synthetic and natural macromolecules: I. Synthesis and physico-chemical characterisation

Journal of controlled release, 2000-02, Vol.64 (1), p.63-79

2000

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Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice

Journal of controlled release, 2004-02, Vol.95 (1), p.83-92

2004

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Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs

Journal of controlled release, 2002-01, Vol.78 (1), p.97-114

2002

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Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences

Journal of controlled release, 2008-04, Vol.127 (2), p.110-120

2008

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A Possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier

European journal of cancer (1990), 1999-03, Vol.35 (3), p.459-466

1999

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HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia

European journal of cancer (1990), 2002-03, Vol.38 (4), p.602-608

2002

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Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators

Journal of controlled release, 2000-02, Vol.64 (1-3), p.241

2000

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Antiproliferative Effect of a Lectin- and Anti-Thy-1.2 Antibody-Targeted HPMA Copolymer-Bound Doxorubicin on Primary and Metastatic Human Colorectal Carcinoma and on Human Colorectal Carcinoma Transfected with the Mouse Thy-1.2 Gene

Bioconjugate chemistry, 2000-09, Vol.11 (5), p.664-673

2000

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Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer–doxorubicin conjugates directed against different T-cell surface antigens

Journal of controlled release, 1998-03, Vol.52 (3), p.253-270

1998

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Poly [N -(2-hydroxypropyl)methacrylamide] Conjugates of Bovine Pancreatic Ribonuclease (RNase A) Inhibit Growth of Human Melanoma in Nude Mice

Journal of drug targeting, 2002-05, Vol.10 (3), p.175-183

2002

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Polymeric drugs based on conjugates of synthetic and natural macromolecules.: II. Anti-cancer activity of antibody or (Fab′) 2-targeted conjugates and combined therapy with immunomodulators

Journal of controlled release, 2000-02, Vol.64 (1), p.241-261

2000

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Immunoprotective therapy with targeted anticancer drugs

Macromolecular symposia., 2001-07, Vol.172 (1), p.21-28

2001

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Cytotoxic and cytostatic effects of anti-Thy 1.2 targeted doxorubicin and cyclosporin A

Journal of controlled release, 1996-07, Vol.40 (3), p.303-319

1996

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Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

Journal of controlled release, 2005-12, Vol.110 (1), p.119-129

2005

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Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data

Journal of controlled release, 2003-08, Vol.91 (1), p.1-16

2003

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Bioaffinity therapy with antibodies and drugs bound to soluble synthetic polymers

Journal of chromatography, 1986-04, Vol.376, p.221-233

1986

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The Activity of Complement in the Presence of N-(2-hydroxypropyl)methacrylamide Copolymers

Journal of bioactive and compatible polymers, 1986-01, Vol.1 (1), p.20-31

1986

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Polymer conjugated bovine seminal ribonuclease inhibits growth of solid tumors and development of metastases in mice

Neoplasma, 2001, Vol.48 (2), p.127

2001

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Different handling of antigen by macrophages of low-responder C57BL/10ScSn strain and high-responder A/J strain of mice. II. Antigen uptake

Folia biologica, 1989, Vol.35 (2), p.90

1989

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Polymeric drugs based on conjugates of synthetic and natural macromolecules

Journal of controlled release, 2000-02, Vol.64 (1-3), p.63-79

2000

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Polymeric drugs based on conjugates of synthetic and natural macromolecules

Journal of controlled release, 2000-02, Vol.64 (1-3), p.241-261

2000

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HPMA-hydrogels containing cytostatic drugs: Kinetics of the drug release and in vivo efficacy

Journal of controlled release, 2002-05, Vol.81 (1), p.101-111

2002

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Drug-HPMA-HuIg conjugates effective against human solid cancer

Advances in experimental medicine and biology, 2003, Vol.519, p.125

2003

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Antibody-targeted polymer-bound drugs

Immunology letters, 1997-05, Vol.56, p.225-225

1997

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Use of targeted drugs in antineoplastic and immunosuppressive therapy

Bratislavské lékarské listy, 1998-08, Vol.99 (8-9), p.439

1998

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Polymeric drugs based on conjugates of synthetic and natural macromolecules: I. Synthesis and physico-chemical characterisation

Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice

Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences

A Possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier

HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia

Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators

Antiproliferative Effect of a Lectin- and Anti-Thy-1.2 Antibody-Targeted HPMA Copolymer-Bound Doxorubicin on Primary and Metastatic Human Colorectal Carcinoma and on Human Colorectal Carcinoma Transfected with the Mouse Thy-1.2 Gene

Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer–doxorubicin conjugates directed against different T-cell surface antigens

Poly [N -(2-hydroxypropyl)methacrylamide] Conjugates of Bovine Pancreatic Ribonuclease (RNase A) Inhibit Growth of Human Melanoma in Nude Mice

Polymeric drugs based on conjugates of synthetic and natural macromolecules.: II. Anti-cancer activity of antibody or (Fab′) 2-targeted conjugates and combined therapy with immunomodulators

Immunoprotective therapy with targeted anticancer drugs

Cytotoxic and cytostatic effects of anti-Thy 1.2 targeted doxorubicin and cyclosporin A

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data

Bioaffinity therapy with antibodies and drugs bound to soluble synthetic polymers

The Activity of Complement in the Presence of N-(2-hydroxypropyl)methacrylamide Copolymers

Polymer conjugated bovine seminal ribonuclease inhibits growth of solid tumors and development of metastases in mice

Different handling of antigen by macrophages of low-responder C57BL/10ScSn strain and high-responder A/J strain of mice. II. Antigen uptake

Polymeric drugs based on conjugates of synthetic and natural macromolecules

Polymeric drugs based on conjugates of synthetic and natural macromolecules

HPMA-hydrogels containing cytostatic drugs: Kinetics of the drug release and in vivo efficacy

Drug-HPMA-HuIg conjugates effective against human solid cancer

Antibody-targeted polymer-bound drugs

Use of targeted drugs in antineoplastic and immunosuppressive therapy

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