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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Molecular cancer therapeutics, 2017-06, Vol.16 (6), p.1010-1020

2017

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Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

Nature communications, 2019-04, Vol.10 (1), p.1856-1856, Article 1856

2019

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Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression

Clinical cancer research, 2017-09, Vol.23 (17), p.5091-5100

2017

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Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib

Molecular cancer therapeutics, 2017-08, Vol.16 (8), p.1717-1726

2017

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Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (14), p.6899-6906

2007

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Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2015-10, Vol.33 (30), p.3401-3408

2015

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Heterochromatic Deposition of Centromeric Histone H3-Like Proteins

Proceedings of the National Academy of Sciences - PNAS, 2000-01, Vol.97 (2), p.716-721

2000

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Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (16), p.6522-6530

2009

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The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

BMC cell biology, 2008-01, Vol.9 (1), p.4, Article 4

2008

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Molecular Pathology in Drug Discovery and Development

Platero, J. Suso

1, 2009

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Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila

The Journal of cell biology, 1998-03, Vol.140 (6), p.1297-1306

1998

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Human Mitochondrial Carbonic Anhydrase: cDNA Cloning, Expression, Subcellular Localization, and Mapping to Chromosome 16

Proceedings of the National Academy of Sciences - PNAS, 1993-08, Vol.90 (16), p.7623-7627

1993

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Phase 1 study of JNJ-42756493, a pan-fibroblast growth factor receptor (FGFR) inhibitor, in patients with advanced solid tumors

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.2501-2501

2014

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Functional analysis of the chromo domain of HP1

The EMBO journal, 1995-08, Vol.14 (16), p.3977-3986

1995

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Frequency of actionable genomic alterations in early-stage lung adenocarcinoma (LA) detected by next-generation sequencing (NGS)

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.e17541-e17541

2012

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Mitochondrial Carbonic Anhydrase (Isozyme V) in Mouse and Rat: cDNA Cloning, Expression, Subcellular Localization, Processing, and Tissue Distribution

Proceedings of the National Academy of Sciences - PNAS, 1994-10, Vol.91 (22), p.10330-10334

1994

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A Distal Heterochromatic Block Displays Centromeric Activity When Detached from a Natural Centromere

Molecular cell, 1999-12, Vol.4 (6), p.995-1004

1999

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Ig/EBP-1 : a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP

Genes & development, 1990-08, Vol.4 (8), p.1404-1415

1990

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In vivo assay for protein-protein interactions using Drosophila chromosomes

Chromosoma, 1996-03, Vol.104 (6), p.393-404

1996

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Changes in chromosomal localization of heterochromatic-binding proteins during the cell cycle in Drosophila

The Journal of cell biology, 1998-03, Vol.140 (6), p.1297

1998

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Aqua® Technology and Molecular Pathology

Molecular Pathology in Drug Discovery and Development, 2009, p.295-333

2009

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Molecular Pathology and Drug Development

Molecular Pathology in Drug Discovery and Development, 2009, p.1-20

2009

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Molecular Pathology in Life‐Cycle Management in Drug Development

Molecular Pathology in Drug Discovery and Development, 2009, p.169-193

2009

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Molecular Pathology as a Way to Find the Right Dose for a Drug

Molecular Pathology in Drug Discovery and Development, 2009, p.143-168

2009

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Molecular Pathology and Molecular Therapy

Molecular Pathology in Drug Discovery and Development, 2009, p.195-220

2009

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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression

Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib

Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist

Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors

Heterochromatic Deposition of Centromeric Histone H3-Like Proteins

Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer

The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

Molecular Pathology in Drug Discovery and Development

Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila

Human Mitochondrial Carbonic Anhydrase: cDNA Cloning, Expression, Subcellular Localization, and Mapping to Chromosome 16

Phase 1 study of JNJ-42756493, a pan-fibroblast growth factor receptor (FGFR) inhibitor, in patients with advanced solid tumors

Functional analysis of the chromo domain of HP1

Frequency of actionable genomic alterations in early-stage lung adenocarcinoma (LA) detected by next-generation sequencing (NGS)

Mitochondrial Carbonic Anhydrase (Isozyme V) in Mouse and Rat: cDNA Cloning, Expression, Subcellular Localization, Processing, and Tissue Distribution

A Distal Heterochromatic Block Displays Centromeric Activity When Detached from a Natural Centromere

Ig/EBP-1 : a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP

In vivo assay for protein-protein interactions using Drosophila chromosomes

Changes in chromosomal localization of heterochromatic-binding proteins during the cell cycle in Drosophila

Aqua® Technology and Molecular Pathology

Molecular Pathology and Drug Development

Molecular Pathology in Life‐Cycle Management in Drug Development

Molecular Pathology as a Way to Find the Right Dose for a Drug

Molecular Pathology and Molecular Therapy

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