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Gamma‐H2AX immunofluorescence for the detection of tissue‐specific genotoxicity in vivo

Environmental and molecular mutagenesis, 2019-01, Vol.60 (1), p.4-16

2019

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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.45-76

2015

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Inter-laboratory comparison of the in vivo comet assay including three image analysis systems

Environmental and molecular mutagenesis, 2015-12, Vol.56 (9), p.788-793

2015

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Evaluation of two in vitro assays for tumorigenicity assessment of CRISPR-Cas9 genome-edited cells

Molecular therapy. Methods & clinical development, 2021-12, Vol.23, p.241-253

2021

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The photo comet assay—A fast screening assay for the determination of photogenotoxicity in vitro

Mutation research, 2007-08, Vol.632 (1), p.44-57

2007

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Repair of Sparfloxacin-Induced Photochemical DNA Damage In Vivo

Journal of investigative dermatology, 2009-03, Vol.129 (3), p.699-704

2009

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DNA damage in human leukocytes after ischemia/reperfusion injury

Free radical biology & medicine, 2000-01, Vol.28 (1), p.1-12

2000

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Use of the alkaline in vivo Comet assay for mechanistic genotoxicity investigations

Mutagenesis, 2004-01, Vol.19 (1), p.51-59

2004

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part III: The Comet Assay as an Alternative to In Vitro Clastogenicity Tests for Early Drug Candidate Selection

Toxicological sciences, 2007-05, Vol.97 (1), p.21-26

2007

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Laser pyrolysis products—genotoxic, clastogenic and mutagenic effects of the particulate aerosol fractions

Mutation research, 1999-04, Vol.441 (1), p.29-41

1999

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Comparative study with the alkaline Comet assay and the chromosome aberration test

Mutation research, 2003-04, Vol.536 (1), p.27-38

2003

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In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data

Regulatory toxicology and pharmacology, 2024-03, Vol.148, p.105583-105583, Article 105583

2024

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Characterization of vemurafenib phototoxicity in a mouse model

Toxicological sciences, 2014-01, Vol.137 (1), p.259-267

2014

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Short-Term Effects of Early-Acting and Multilineage HematoPoietic Growth Factors on the Repair and Proliferation of Irradiated Pure Cord Blood (CB) CD34 Hematopoietic Progenitor Cells

International journal of radiation oncology, biology, physics, 1998-03, Vol.40 (5), p.1193-1203

1998

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Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation

Environmental and molecular mutagenesis, 1997, Vol.30 (2), p.153-160

1997

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-05, Vol.783, p.6-12

2015

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Evaluation of methyl methanesulfonate, 2,6-diaminotoluene and 5-fluorouracil: Part of the Japanese center for the validation of alternative methods (JaCVAM) international validation study of the in vivo rat alkaline comet assay

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.120-124

2015

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Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

Mutation research, 2011-08, Vol.723 (2), p.108-120

2011

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Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

Mutation research, 2010-09, Vol.702 (1), p.40-69

2010

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A modified oral UV-LLNA in Balb/c mice to investigate phototoxicity mechanisms and pharmacokinetic properties in skin

Toxicology letters, 2013-08, Vol.221, p.S87-S88

2013

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Performance and data interpretation of the in vivo comet assay in pharmaceutical industry: EFPIA survey results

Mutation research. Genetic toxicology and environmental mutagenesis, 2014-12, Vol.775-776, p.81-88

2014

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Does physical activity induce DNA damage?

Mutagenesis, 1994-05, Vol.9 (3), p.269-272

1994

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Detection of photogenotoxicity in skin and eye in rat with the photo comet assay

Photochemical & photobiological sciences, 2008-02, Vol.7 (2), p.240-249

2008

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Repair of Sparfloxacin-lnduced Photochemical DNA Damage In Vivo

Journal of investigative dermatology, 2009, Vol.129 (3), p.699-704

2009

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Photodegradation analysis as additional tool to verify phototoxicity

Toxicology (Amsterdam), 2006-09, Vol.226 (1), p.70-71

2006

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Gamma‐H2AX immunofluorescence for the detection of tissue‐specific genotoxicity in vivo

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Inter-laboratory comparison of the in vivo comet assay including three image analysis systems

Evaluation of two in vitro assays for tumorigenicity assessment of CRISPR-Cas9 genome-edited cells

The photo comet assay—A fast screening assay for the determination of photogenotoxicity in vitro

Repair of Sparfloxacin-Induced Photochemical DNA Damage In Vivo

DNA damage in human leukocytes after ischemia/reperfusion injury

Use of the alkaline in vivo Comet assay for mechanistic genotoxicity investigations

Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part III: The Comet Assay as an Alternative to In Vitro Clastogenicity Tests for Early Drug Candidate Selection

Laser pyrolysis products—genotoxic, clastogenic and mutagenic effects of the particulate aerosol fractions

Comparative study with the alkaline Comet assay and the chromosome aberration test

In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data

Characterization of vemurafenib phototoxicity in a mouse model

Short-Term Effects of Early-Acting and Multilineage HematoPoietic Growth Factors on the Repair and Proliferation of Irradiated Pure Cord Blood (CB) CD34 Hematopoietic Progenitor Cells

Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Evaluation of methyl methanesulfonate, 2,6-diaminotoluene and 5-fluorouracil: Part of the Japanese center for the validation of alternative methods (JaCVAM) international validation study of the in vivo rat alkaline comet assay

Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

A modified oral UV-LLNA in Balb/c mice to investigate phototoxicity mechanisms and pharmacokinetic properties in skin

Performance and data interpretation of the in vivo comet assay in pharmaceutical industry: EFPIA survey results

Does physical activity induce DNA damage?

Detection of photogenotoxicity in skin and eye in rat with the photo comet assay

Repair of Sparfloxacin-lnduced Photochemical DNA Damage In Vivo

Photodegradation analysis as additional tool to verify phototoxicity

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