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Modulation of inflammation by autophagy: Consequences for human disease

Autophagy, 2016-01, Vol.12 (2), p.245-260

2016

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IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3526-3531

2014

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TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

Journal of leukocyte biology, 2013-11, Vol.94 (5), p.885-902

2013

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Human TLR10 is an anti-inflammatory pattern-recognition receptor

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.E4478-E4484

2014

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Assessing thyroid cancer risk using polygenic risk scores

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (11), p.5997-6002

2020

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Early Stop Polymorphism in Human DECTIN-1 Is Associated with Increased Candida Colonization in Hematopoietic Stem Cell Transplant Recipients

Clinical infectious diseases, 2009-09, Vol.49 (5), p.724-732

2009

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PI3K/Akt/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma

Cancer treatment reviews, 2015-09, Vol.41 (8), p.707-713

2015

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Inflammasome-independent modulation of cytokine response by autophagy in human cells

PloS one, 2011-04, Vol.6 (4), p.e18666-e18666

2011

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STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis

PloS one, 2011-12, Vol.6 (12), p.e29248-e29248

2011

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Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade

Cancer research (Chicago, Ill.), 2021-04, Vol.81 (7), p.1775-1787

2021

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STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

The New England journal of medicine, 2011-07, Vol.365 (1), p.54-61

2011

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Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Cancer discovery, 2022-05, Vol.12 (5), p.1248-1265

2022

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Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

Gut, 2011-09, Vol.60 (9), p.1229-1235

2011

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An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy

Molecular cancer therapeutics, 2024-02, Vol.23 (2), p.187

2024

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Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2668-2673

2014

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Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome

PloS one, 2014-04, Vol.9 (4), p.e94086

2014

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MEFV mutations affecting pyrin amino acid 577 cause autosomal dominant autoinflammatory disease

Annals of the rheumatic diseases, 2014-02, Vol.73 (2), p.455-461

2014

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Polymorphisms in autophagy genes and susceptibility to tuberculosis

PloS one, 2012-08, Vol.7 (8), p.e41618-e41618

2012

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Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages

Oncoimmunology, 2016-12, Vol.5 (12), p.e1229725-e1229725

2016

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Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Nature communications, 2013-01, Vol.4 (1), p.1342-1342, Article 1342

2013

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Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines

Carcinogenesis (New York), 2016-02, Vol.37 (2), p.197-205

2016

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The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

Journal of leukocyte biology, 2011-08, Vol.90 (2), p.357-366

2011

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Pathological processes and therapeutic advances in radioiodide refractory thyroid cancer

Journal of molecular endocrinology, 2017-11, Vol.59 (4), p.R141-R154

2017

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A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.25742-25748

2009

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Autophagy modulates the Mycobacterium tuberculosis‐induced cytokine response

Immunology, 2011-11, Vol.134 (3), p.341-348

2011

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Modulation of inflammation by autophagy: Consequences for human disease

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

Human TLR10 is an anti-inflammatory pattern-recognition receptor

Assessing thyroid cancer risk using polygenic risk scores

Early Stop Polymorphism in Human DECTIN-1 Is Associated with Increased Candida Colonization in Hematopoietic Stem Cell Transplant Recipients

PI3K/Akt/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma

Inflammasome-independent modulation of cytokine response by autophagy in human cells

STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis

Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade

STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome

MEFV mutations affecting pyrin amino acid 577 cause autosomal dominant autoinflammatory disease

Polymorphisms in autophagy genes and susceptibility to tuberculosis

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

Pathological processes and therapeutic advances in radioiodide refractory thyroid cancer

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

Autophagy modulates the Mycobacterium tuberculosis‐induced cytokine response

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