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ADME properties of CHF6366, a novel bi-functional M3 muscarinic receptor antagonist and ß2 adrenoceptor agonist (MABA) radiolabelled at both functional moieties

Xenobiotica, 2023-07, Vol.ahead-of-print (ahead-of-print), p.1-21

2023

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ADME properties of CHF6366, a novel bi-functional M3 muscarinic receptor antagonist and ß 2 adrenoceptor agonist (MABA) radiolabelled at both functional moieties

Xenobiotica, 2023-04, Vol.53 (4), p.288-308

2023

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Stereoselective synthesis of 3,4‐dihydropyrrolopyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids

Chirality (New York, N.Y.), 2022-11, Vol.34 (11), p.1437-1452

2022

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Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids

Chirality (New York, N.Y.), 2022-11, Vol.34 (11), p.1437-1452

2022

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Plasma-enhanced protein patterning in a microfluidic compartmentalized platform for multi-organs-on-chip: a liver-tumor model

Biomedical materials (Bristol), 2021-07, Vol.16 (4), p.45032

2021

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ChemInform Abstract: The Piancatelli Rearrangement: New Applications for an Intriguing Reaction

ChemInform, 2014-06, Vol.45 (23), p.no-no

2014

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Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases

Bioorganic & medicinal chemistry, 2013-12, Vol.21 (23), p.7364-7380

2013

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The Piancatelli rearrangement: new applications for an intriguing reaction

Molecules, 2013-10, Vol.18 (10), p.12290-12312

2013

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ChemInform Abstract: A Submarine Journey: The Pyrrole--Imidazole Alkaloids

ChemInform, 2010-05, Vol.41 (21), p.no-no

2010

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A submarine journey: the pyrrole-imidazole alkaloids

Marine Drugs, 2009-11, Vol.7 (4), p.705-753

2009

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.5058-5058

2005

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization

Journal of medicinal chemistry, 2005-04, Vol.48 (8), p.2944-2956

2005

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

Journal of medicinal chemistry, 2004-06, Vol.47 (13), p.3367-3380

2004

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3-aminopyrazole inhibitors of CDK/cyclin A as antitumor agents. 1. Lead finding

Journal of medicinal chemistry, 2004, Vol.47 (13), p.3367-3380

2004

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Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine Using Solid-Supported Reagents

ChemInform, 2002-12, Vol.33 (50), p.179-179

2002

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Total synthesis of the amaryllidaceae alkaloid (+)-plicamine using solid-supported reagents

Tetrahedron, 2002-08, Vol.58 (32), p.6285-6304

2002

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Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions

Angewandte Chemie (International ed.), 2002-06, Vol.41 (12), p.2194-2197

2002

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Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions

Angewandte Chemie, 2002-06, Vol.114 (12), p.2298-2301

2002

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Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions We gratefully acknowledge financial support from Pfizer Central Research for a Postdoctoral Fellowship (to I.R.B.), the BP endowment and the Novartis Research Fellowship (to S.V.L.), and Pharmacia & Upjohn (to C.P.)

Angewandte Chemie International Edition, 2002-06, Vol.41 (12), p.2194

2002

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Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions We gratefully acknowledge financial support from Pfizer Central Research for a Postdoctoral Fellowship (to I.R.B.), the BP endowment and the Novartis Research Fellowship (to S.V.L.), and Pharmacia & Upjohn (to C.P.)

Angewandte Chemie, 2002-06, Vol.114 (12), p.2298

2002

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Identification of Shc docking site on Ret tyrosine kinase

Oncogene, 1997-02, Vol.14 (7), p.773-782

1997

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The Full Oncogenic Activity of Ret/ptc2 Depends on Tyrosine 539, a Docking Site for Phospholipase Cγ

Molecular and cellular biology, 1996-05, Vol.16 (5), p.2151-2163

1996

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Phosphorylated residues as specificity determinants for an acidophilic protein tyrosine kinase: A study with src and cdc2 derived phosphopeptides

FEBS letters, 1993-09, Vol.330 (2), p.141-145

1993

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Phosphorylated residues as specificity determinants for an acidophilic protein tyrosine kinase

FEBS letters, 1993-09, Vol.330 (2), p.141-145

1993

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ADME properties of CHF6366, a novel bi-functional M3 muscarinic receptor antagonist and ß2 adrenoceptor agonist (MABA) radiolabelled at both functional moieties

ADME properties of CHF6366, a novel bi-functional M3 muscarinic receptor antagonist and ß 2 adrenoceptor agonist (MABA) radiolabelled at both functional moieties

Stereoselective synthesis of 3,4‐dihydropyrrolopyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids

Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids

Plasma-enhanced protein patterning in a microfluidic compartmentalized platform for multi-organs-on-chip: a liver-tumor model

ChemInform Abstract: The Piancatelli Rearrangement: New Applications for an Intriguing Reaction

Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases

The Piancatelli rearrangement: new applications for an intriguing reaction

ChemInform Abstract: A Submarine Journey: The Pyrrole--Imidazole Alkaloids

A submarine journey: the pyrrole-imidazole alkaloids

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

3-aminopyrazole inhibitors of CDK/cyclin A as antitumor agents. 1. Lead finding

Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine Using Solid-Supported Reagents

Total synthesis of the amaryllidaceae alkaloid (+)-plicamine using solid-supported reagents

Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions

Total Synthesis of the Amaryllidaceae Alkaloid (+)-Plicamine and Its Unnatural Enantiomer by Using Solid-Supported Reagents and Scavengers in a Multistep Sequence of Reactions

Identification of Shc docking site on Ret tyrosine kinase

The Full Oncogenic Activity of Ret/ptc2 Depends on Tyrosine 539, a Docking Site for Phospholipase Cγ

Phosphorylated residues as specificity determinants for an acidophilic protein tyrosine kinase: A study with src and cdc2 derived phosphopeptides

Phosphorylated residues as specificity determinants for an acidophilic protein tyrosine kinase

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