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IL-22 induces an acute-phase response

The Journal of immunology (1950), 2010-11, Vol.185 (9), p.5531-5538

2010

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Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Blood, 2020-02, Vol.135 (8), p.547-557

2020

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Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Blood, 2021-04, Vol.137 (15), p.2010-2020

2021

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Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Haemophilia : the official journal of the World Federation of Hemophilia, 2019-09, Vol.25 (5), p.797-806

2019

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Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti–Tissue Factor Pathway Inhibitor Antibody, PF-06741086

Journal of pharmaceutical sciences, 2018-07, Vol.107 (7), p.1995-2004

2018

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Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection

Critical care (London, England), 2007-01, Vol.11 (6), p.R122-R122, Article R122

2007

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Validation of patient‐reported vaso‐occlusive crisis day as an endpoint in sickle cell disease studies

European journal of haematology, 2022-09, Vol.109 (3), p.226-237

2022

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Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species

The AAPS journal, 2019-04, Vol.21 (3), p.52-52, Article 52

2019

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Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model

Research and practice in thrombosis and haemostasis, 2022-02, Vol.6 (2), p.e12679-n/a, Article e12679

2022

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PF‐04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo‐Controlled Study

Clinical and translational science, 2019-03, Vol.12 (2), p.180-188

2019

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Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor XaI16L

Journal of pharmaceutical sciences, 2017-08, Vol.106 (8), p.2136-2143

2017

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Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor Xa I16L

Journal of pharmaceutical sciences, 2017-08, Vol.106 (8), p.2136-2143

2017

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Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner

The Journal of immunology (1950), 2010-10, Vol.185 (7), p.4213-4222

2010

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A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia

Shock (Augusta, Ga.), 2011-05, Vol.35 (5), p.492-498

2011

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TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines

Rheumatology (Oxford, England), 2009-11, Vol.48 (11), p.1352-1358

2009

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Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells

Biochemical and biophysical research communications, 2011-06, Vol.409 (3), p.500-505

2011

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Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

Atherosclerosis, 2008-11, Vol.201 (1), p.53-66

2008

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Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

Journal of molecular biology, 2009-05, Vol.388 (3), p.541-558

2009

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Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice

mAbs, 2010-09, Vol.2 (5), p.571-575

2010

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Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis

Molecular medicine (Cambridge, Mass.), 2007-01, Vol.13 (1-2), p.40-58

2007

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Proteomic Identification of Endothelial Proteins Isolated in Situ from Atherosclerotic Aorta via Systemic Perfusion

Journal of proteome research, 2007-12, Vol.6 (12), p.4728-4736

2007

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A gene expression profile for endochondral bone formation: oligonucleotide microarrays establish novel connections between known genes and BMP-2-induced bone formation in mouse quadriceps

Bone (New York, N.Y.), 2003-07, Vol.33 (1), p.46-63

2003

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Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer

Molecular therapy, 2002-10, Vol.6 (4), p.464-470

2002

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Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Blood, 2018-11, Vol.132 (Supplement 1), p.2460-2460

2018

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Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Blood, 2018-11, Vol.132 (Supplement 1), p.1049-1049

2018

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IL-22 induces an acute-phase response

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti–Tissue Factor Pathway Inhibitor Antibody, PF-06741086

Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection

Validation of patient‐reported vaso‐occlusive crisis day as an endpoint in sickle cell disease studies

Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species

Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model

PF‐04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo‐Controlled Study

Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor XaI16L

Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor Xa I16L

Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner

A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia

TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines

Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells

Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice

Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis

Proteomic Identification of Endothelial Proteins Isolated in Situ from Atherosclerotic Aorta via Systemic Perfusion

A gene expression profile for endochondral bone formation: oligonucleotide microarrays establish novel connections between known genes and BMP-2-induced bone formation in mouse quadriceps

Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

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