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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Nature medicine, 2017-07, Vol.23 (7), p.878-884

2017

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Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Cell, 2022-06, Vol.185 (13), p.2213-2233.e25

2022

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Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease

The Journal of experimental medicine, 2012-12, Vol.209 (13), p.2501-2513

2012

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Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5620-5625

2011

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A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele

The Journal of neuroscience, 2015-05, Vol.35 (21), p.8091-8106

2015

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Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells

Journal of lipid research, 2017-04, Vol.58 (4), p.695-708

2017

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HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

Journal of lipid research, 2021-01, Vol.62, p.100114-100114, Article 100114

2021

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STARD4 abundance regulates sterol transport and sensing

Molecular biology of the cell, 2011-11, Vol.22 (21), p.4004-4015

2011

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Improvement in Lipid and Protein Trafficking in Niemann-Pick C1 Cells by Correction of a Secondary Enzyme Defect

Traffic (Copenhagen, Denmark), 2010-05, Vol.11 (5), p.601-615

2010

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Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells

PloS one, 2010-09, Vol.5 (9), p.e12788-e12788

2010

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Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary

PloS one, 2012-10, Vol.7 (10), p.e47320

2012

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Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells

Journal of lipid research, 2006-02, Vol.47 (2), p.284-301

2006

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Role of STARD4 and NPC1 in intracellular sterol transport

Biochemistry and cell biology, 2016-12, Vol.94 (6), p.499-506

2016

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2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-10, Vol.1864 (10), p.1545-1561

2019

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Sterol, Protein and Lipid Trafficking in Chinese Hamster Ovary Cells with Niemann‐Pick Type C1 Defect

Traffic (Copenhagen, Denmark), 2007-02, Vol.8 (2), p.130-141

2007

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Therapeutic potential of histone deacetylase inhibitor for treatment of Niemann-Pick type C1 disease

Molecular cytogenetics, 2014-01, Vol.7 (Suppl 1), p.O2-O2

2014

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A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20752-20761

2005

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Targeting molecular chaperone HSP90 to treat Niemann‐Pick type C1 disease

The FASEB journal, 2018-04, Vol.32 (S1), p.814.7-814.7

2018

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The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: Fluorescence and molecular dynamics studies of free and bound alpha spectrin

Protein science, 2009-09, Vol.18 (9), p.1916-1925

2009

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Targeting Molecular Chaperone HSP90 To Treat Niemann‐Pick Type C1 Disease

The FASEB journal, 2019-04, Vol.33 (S1), p.490.11-490.11

2019

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Human glia‐specific functional dysregulations affected by APOE ε4 risk of Alzheimer's disease

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Human glia‐specific functional dysregulations affected by APOE ε4 risk of Alzheimer's disease: Molecular and cell biology/stem cells, iPS cells

Alzheimer's & dementia, 2020-12, Vol.16 (S3)

2020

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Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays

Combinatorial chemistry & high throughput screening, 2006-11, Vol.9 (9), p.711-718

2006

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Erratum: Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Nature medicine, 2018-04, Vol.24 (4), p.526-526

2018

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Correction: Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Nature medicine, 2018-04, Vol.24 (4), p.526-526

2018

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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele

Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells

HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

STARD4 abundance regulates sterol transport and sensing

Improvement in Lipid and Protein Trafficking in Niemann-Pick C1 Cells by Correction of a Secondary Enzyme Defect

Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells

Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary

Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells

Role of STARD4 and NPC1 in intracellular sterol transport

2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease

Sterol, Protein and Lipid Trafficking in Chinese Hamster Ovary Cells with Niemann‐Pick Type C1 Defect

Therapeutic potential of histone deacetylase inhibitor for treatment of Niemann-Pick type C1 disease

A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells

Targeting molecular chaperone HSP90 to treat Niemann‐Pick type C1 disease

The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: Fluorescence and molecular dynamics studies of free and bound alpha spectrin

Targeting Molecular Chaperone HSP90 To Treat Niemann‐Pick Type C1 Disease

Human glia‐specific functional dysregulations affected by APOE ε4 risk of Alzheimer's disease

Human glia‐specific functional dysregulations affected by APOE ε4 risk of Alzheimer's disease: Molecular and cell biology/stem cells, iPS cells

Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays

Erratum: Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Correction: Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

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