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Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis

Journal of the neurological sciences, 2020-10, Vol.417, p.117054-117054, Article 117054

2020

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Trajectories of impairment in amyotrophic lateral sclerosis: Insights from the Pooled Resource Open‐Access ALS Clinical Trials cohort

Muscle & nerve, 2018-06, Vol.57 (6), p.937-945

2018

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Graph theory network analysis provides brain MRI evidence of a partial continuum of neurodegeneration in patients with UMN-predominant ALS and ALS-FTD

NeuroImage clinical, 2022-01, Vol.35, p.103037-103037, Article 103037

2022

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Unbiased MRI Analyses Identify Micropathologic Differences Between Upper Motor Neuron-Predominant ALS Phenotypes

Frontiers in neuroscience, 2019-07, Vol.13, p.704-704

2019

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Dextromethorphan Plus Ultra Low-Dose Quinidine Reduces Pseudobulbar Affect

Annals of neurology, 2010-11, Vol.68 (5), p.693-702

2010

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Control of microglial neurotoxicity by the fractalkine receptor

Nature neuroscience, 2006-07, Vol.9 (7), p.917-924

2006

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Brain white matter shape changes in amyotrophic lateral sclerosis (ALS): a fractal dimension study

PloS one, 2013-09, Vol.8 (9), p.e73614-e73614

2013

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Differential involvement of corticospinal tract (CST) fibers in UMN-predominant ALS patients with or without CST hyperintensity: A diffusion tensor tractography study

NeuroImage clinical, 2017-01, Vol.14 (C), p.574-579

2017

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Corticospinal Tract and Related Grey Matter Morphometric Shape Analysis in ALS Phenotypes: A Fractal Dimension Study

Brain sciences, 2021-03, Vol.11 (3), p.371

2021

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A new method for estimating under-recruitment of a patient registry: a case study with the Ohio Registry of Amyotrophic Lateral Sclerosis

Scientific reports, 2022-08, Vol.12 (1), p.14721-14721, Article 14721

2022

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Quantitative Brain MRI Metrics Distinguish Four Different ALS Phenotypes: A Machine Learning Based Study

Diagnostics (Basel), 2023-04, Vol.13 (9), p.1521

2023

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Differing patterns of cortical grey matter pathology identified by multifractal analysis in UMN-predominant ALS patients with and without corticospinal tract hyperintensity

Journal of the neurological sciences, 2024-04, Vol.459, p.122945-122945, Article 122945

2024

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Graph network measures reveal distinct white matter abnormalities in motor and extra-motor brain regions of two UMN-predominant ALS subtypes

Journal of the neurological sciences, 2023-09, Vol.452, p.120765-120765, Article 120765

2023

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Hypometabolic and hypermetabolic brain regions in patients with ALS-FTD show distinct patterns of grey and white matter degeneration: A pilot multimodal neuroimaging study

European journal of radiology, 2023-01, Vol.158, p.110616-110616, Article 110616

2023

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Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

EMBO molecular medicine, 2021-01, Vol.13 (1), p.e12595-n/a

2021

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Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes

Stem cell research, 2021-01, Vol.50, p.102141-102141, Article 102141

2021

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Lack of evidence of monomer/misfolded superoxide dismutase-1 in sporadic amyotrophic lateral sclerosis

Annals of neurology, 2009-07, Vol.66 (1), p.75-80

2009

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Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (29), p.12860-12865

2010

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Racing against the clock: Recognizing, differentiating, diagnosing, and referring the amyotrophic lateral sclerosis patient

Annals of neurology, 2009-01, Vol.65 (S1), p.S10-S16

2009

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Comparing brain structural MRI and metabolic FDG-PET changes in patients with ALS-FTD: ‘the chicken or the egg?’ question

Journal of neurology, neurosurgery and psychiatry, 2015-09, Vol.86 (9), p.952-958

2015

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Self-reported factors contributing to delay in ALS diagnosis among primary care providers in a large Ohio-based US healthcare network

Journal of the neurological sciences, 2023-02, Vol.445, p.120532-120532, Article 120532

2023

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Laughter, crying and sadness in ALS

Journal of neurology, neurosurgery and psychiatry, 2017-10, Vol.88 (10), p.825

2017

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Neuroimaging in primary lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2020-11, Vol.21 (S1), p.18-27

2020

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Depression in ALS in a large self-reporting cohort

Neurology, 2016-03, Vol.86 (11), p.1031

2016

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Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis

Trajectories of impairment in amyotrophic lateral sclerosis: Insights from the Pooled Resource Open‐Access ALS Clinical Trials cohort

Graph theory network analysis provides brain MRI evidence of a partial continuum of neurodegeneration in patients with UMN-predominant ALS and ALS-FTD

Unbiased MRI Analyses Identify Micropathologic Differences Between Upper Motor Neuron-Predominant ALS Phenotypes

Dextromethorphan Plus Ultra Low-Dose Quinidine Reduces Pseudobulbar Affect

Control of microglial neurotoxicity by the fractalkine receptor

Brain white matter shape changes in amyotrophic lateral sclerosis (ALS): a fractal dimension study

Differential involvement of corticospinal tract (CST) fibers in UMN-predominant ALS patients with or without CST hyperintensity: A diffusion tensor tractography study

Corticospinal Tract and Related Grey Matter Morphometric Shape Analysis in ALS Phenotypes: A Fractal Dimension Study

A new method for estimating under-recruitment of a patient registry: a case study with the Ohio Registry of Amyotrophic Lateral Sclerosis

Quantitative Brain MRI Metrics Distinguish Four Different ALS Phenotypes: A Machine Learning Based Study

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III

Differing patterns of cortical grey matter pathology identified by multifractal analysis in UMN-predominant ALS patients with and without corticospinal tract hyperintensity

Graph network measures reveal distinct white matter abnormalities in motor and extra-motor brain regions of two UMN-predominant ALS subtypes

Hypometabolic and hypermetabolic brain regions in patients with ALS-FTD show distinct patterns of grey and white matter degeneration: A pilot multimodal neuroimaging study

Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes

Lack of evidence of monomer/misfolded superoxide dismutase-1 in sporadic amyotrophic lateral sclerosis

Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex

Racing against the clock: Recognizing, differentiating, diagnosing, and referring the amyotrophic lateral sclerosis patient

Comparing brain structural MRI and metabolic FDG-PET changes in patients with ALS-FTD: ‘the chicken or the egg?’ question

Self-reported factors contributing to delay in ALS diagnosis among primary care providers in a large Ohio-based US healthcare network

Laughter, crying and sadness in ALS

Neuroimaging in primary lateral sclerosis

Depression in ALS in a large self-reporting cohort

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