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Biological Effects on μ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives

Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5448

2021

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Plasma L-ergothioneine measurement by high-performance liquid chromatography and capillary electrophoresis after a pre-column derivatization with 5-iodoacetamidofluorescein (5-IAF) and fluorescence detection

PloS one, 2013-07, Vol.8 (7), p.e70374-e70374

2013

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Development of an LC⁻Tandem Mass Spectrometry Method for the Quantitative Analysis of Hercynine in Human Whole Blood

Molecules (Basel, Switzerland), 2018-12, Vol.23 (12), p.3326

2018

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Enantiomeric reversed-phase high-performance liquid chromatography resolution of d-/ l-penicillamine after spirocyclization with ninhydrin and by using copper(II)- l-proline complex as a chiral selector in the mobile phase

Journal of Chromatography A, 2008-09, Vol.1205 (1), p.90-93

2008

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Application of an unusual ninhydrin-based reaction for the indirect chiral resolution of d,l-penicillamine

Talanta (Oxford), 2011-09, Vol.85 (4), p.1783-1785

2011

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Quantification of L-ergothioneine in whole blood by hydrophilic interaction ultra-performance liquid chromatography and UV-detection

Journal of separation science, 2013-03, Vol.36 (6), p.1002-1006

2013

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hydrophilic interaction ultraperformance liquid chromatography (HILIC-UPLC) method for genomic DNA methylation assessment by UV detection

Analytical and bioanalytical chemistry, 2010-04, Vol.396 (8), p.2937-2941

2010

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A new general regression-based approach for method comparison studies

Clinical chemistry and laboratory medicine, 2008-07, Vol.46 (7), p.1046-1049

2008

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Chemistry of Tricyclic-based Heterocycles as Useful Scaffolds for Phosphodiesterase 10A Ligands

Mini-reviews in organic chemistry, 2013-05, Vol.10 (2), p.123-140

2013

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Improved rapid assay of plasma uric acid by short-end injection capillary zone electrophoresis

Analytical and bioanalytical chemistry, 2009-12, Vol.395 (8), p.2577-2582

2009

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Synthesis and SAR study of novel tricyclic pyrazoles as potent phosphodiesterase 10A inhibitors

European journal of medicinal chemistry, 2014-09, Vol.84, p.181-193

2014

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NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile

Behavioural brain research, 2012-10, Vol.234 (2), p.192-204

2012

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A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives

European journal of medicinal chemistry, 2016-10, Vol.121, p.194-208

2016

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Novel diazabicycloalkane delta opioid agonists

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (17), p.5527-5538

2015

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D-Penicillamine Interferes With S-Homocysteinylation and S-Cysteinylation of LDL Apolipoprotein B

Journal of clinical pharmacology, 2011-12, Vol.51 (12), p.1728-1732

2011

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Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake

European journal of medicinal chemistry, 2013-04, Vol.62, p.256-269

2013

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NESS002ie: A new fluorinated thiol endopeptidase inhibitor with antinociceptive activity in an animal model of persistent pain

Pharmacology, biochemistry and behavior, 2013-09, Vol.110, p.137-144

2013

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new selective pre-column ninhydrin-based derivatization for a RP-HPLC determination of plasma asymmetric dimethyl-l-arginine (ADMA) by fluorescence detection

Amino acids, 2008-05, Vol.34 (4), p.677-682

2008

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Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons

European journal of medicinal chemistry, 2013-11, Vol.69, p.413-426

2013

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Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties

Chemical and Pharmaceutical Bulletin, 2001, Vol.49(11), pp.1406-1411

2001

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Synthesis and antiproliferative properties of N 3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine

European journal of medicinal chemistry, 2007-03, Vol.42 (3), p.293-306

2007

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Synthesis and Cytotoxic Activities of Pyrrole[2,3-d]pyridazin-4-one Derivatives

Chemical and Pharmaceutical Bulletin, 2002, Vol.50(6), pp.754-759

2002

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ChemInform Abstract: Chemistry of Tricyclic-based Heterocycles as Useful Scaffolds for Phosphodiesterase 10A Ligands

ChemInform, 2013-12, Vol.44 (52), p.no-no

2013

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NESS06SM reduces body weight with an improved profile relative to SR141716A

Pharmacological research, 2013-08, Vol.74, p.94-108

2013

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Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl )pyridin -4 -yl ]methyl -piperazine

European journal of medicinal chemistry, 2007-03, Vol.42 (3), p.293-306

2007

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Biological Effects on μ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives

Plasma L-ergothioneine measurement by high-performance liquid chromatography and capillary electrophoresis after a pre-column derivatization with 5-iodoacetamidofluorescein (5-IAF) and fluorescence detection

Development of an LC⁻Tandem Mass Spectrometry Method for the Quantitative Analysis of Hercynine in Human Whole Blood

Enantiomeric reversed-phase high-performance liquid chromatography resolution of d-/ l-penicillamine after spirocyclization with ninhydrin and by using copper(II)- l-proline complex as a chiral selector in the mobile phase

Application of an unusual ninhydrin-based reaction for the indirect chiral resolution of d,l-penicillamine

Quantification of L-ergothioneine in whole blood by hydrophilic interaction ultra-performance liquid chromatography and UV-detection

hydrophilic interaction ultraperformance liquid chromatography (HILIC-UPLC) method for genomic DNA methylation assessment by UV detection

A new general regression-based approach for method comparison studies

Chemistry of Tricyclic-based Heterocycles as Useful Scaffolds for Phosphodiesterase 10A Ligands

Improved rapid assay of plasma uric acid by short-end injection capillary zone electrophoresis

Synthesis and SAR study of novel tricyclic pyrazoles as potent phosphodiesterase 10A inhibitors

NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile

A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives

Novel diazabicycloalkane delta opioid agonists

D-Penicillamine Interferes With S-Homocysteinylation and S-Cysteinylation of LDL Apolipoprotein B

Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake

NESS002ie: A new fluorinated thiol endopeptidase inhibitor with antinociceptive activity in an animal model of persistent pain

new selective pre-column ninhydrin-based derivatization for a RP-HPLC determination of plasma asymmetric dimethyl-l-arginine (ADMA) by fluorescence detection

Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons

Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties

Synthesis and antiproliferative properties of N 3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine

Synthesis and Cytotoxic Activities of Pyrrole[2,3-d]pyridazin-4-one Derivatives

ChemInform Abstract: Chemistry of Tricyclic-based Heterocycles as Useful Scaffolds for Phosphodiesterase 10A Ligands

NESS06SM reduces body weight with an improved profile relative to SR141716A

Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl )pyridin -4 -yl ]methyl -piperazine

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