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Loss of Uracil DNA Glycosylase Selectively Resensitizes p53-Mutant and -Deficient Cells to 5-FdU

Molecular cancer research, 2018-02, Vol.16 (2), p.212-221

2018

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Development of β-Lapachone Prodrugs for Therapy Against Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase 1 Levels

Clinical cancer research, 2005-04, Vol.11 (8), p.3055-3064

2005

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HPV infection and EGFR activation/alteration in HIV-infected East African patients with conjunctival carcinoma

PloS one, 2010-05, Vol.5 (5), p.e10477-e10477

2010

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MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model

British journal of cancer, 2016-10, Vol.115 (8), p.920-928

2016

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Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed-Platinum-Radiation in Patients with Advanced Nonsquamous Non-Small Cell Lung Cancer: Results of a Phase I Trial

Clinical cancer research, 2022-02, Vol.28 (4), p.646-652

2022

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Computational Drug Repositioning Identifies Statins as Modifiers of Prognostic Genetic Expression Signatures and Metastatic Behavior in Melanoma

Journal of investigative dermatology, 2021-07, Vol.141 (7), p.1802-1809

2021

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Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers

Molecular cancer therapeutics, 2013-10, Vol.12 (10), p.2110-2120

2013

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Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5306-5320

2013

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Abstract 2816: Evaluation of Cdk5 inhibitors in neural crest tumors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2816-2816

2016

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Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors

Investigational new drugs, 2021-02, Vol.39 (1), p.142-151

2021

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μ-Calpain Activation in β-Lapachone-Mediated Apoptosis

Cancer biology & therapy, 2003-03, Vol.2 (2), p.141-152

2003

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From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation

European journal of medicinal chemistry, 2012-01, Vol.47 (1), p.432-444

2012

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The C-terminus of interferon gamma receptor beta chain (IFNγR2) has antiapoptotic activity as a bax inhibitor

Cancer biology & therapy, 2009-09, Vol.8 (18), p.1771-1786

2009

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Identification of a Class of Novel Tubulin Inhibitors

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3425-3435

2012

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Nuclear Clusterin/XIP8, an X-Ray-Induced Ku70-Binding Protein That Signals Cell Death

Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (11), p.5907-5912

2000

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Interactions between self-assembled polyelectrolyte shells and tumor cells

Journal of biomedical materials research. Part A, 2005-06, Vol.73A (3), p.303-312

2005

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Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines

Cancer research (Chicago, Ill.), 1996-05, Vol.56 (10), p.2321-2330

1996

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Mornings with art, lessons learned: Feedback regulation, restriction threshold biology, and redundancy govern molecular stress responses

Journal of cellular physiology, 2006-12, Vol.209 (3), p.604-610

2006

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Computational drug repositioning identifies statins as a modifier of prognostic genetic expression signatures and metastatic behavior in melanoma

Journal of investigative dermatology, 2021-01, Vol.141 (7), p.1802-1809

2021

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Adding Base Excision Repair Inhibitor TRC102 to standard Pemetrexed-Platinum-Radiation in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Results of a phase I trial

Clinical cancer research, 2022-02, Vol.28 (4), p.646-652

2022

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An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein

Cancer research (Chicago, Ill.), 1995-06, Vol.55 (12), p.2583-2590

1995

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Delayed apoptotic responses associated with radiation-induced neoplastic transformation of human hybrid cells

Cancer research (Chicago, Ill.), 1999-08, Vol.59 (16), p.3972-3979

1999

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HEXIM1 is a critical determinant of the response to tamoxifen

Oncogene, 2011-08, Vol.30 (33), p.3563-3569

2011

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NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

The Journal of biological chemistry, 2000-02, Vol.275 (8), p.5416-5424

2000

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Calcium Is a Key Signaling Molecule in β-Lapachone-mediated Cell Death

The Journal of biological chemistry, 2001-06, Vol.276 (22), p.19150-19159

2001

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Loss of Uracil DNA Glycosylase Selectively Resensitizes p53-Mutant and -Deficient Cells to 5-FdU

Development of β-Lapachone Prodrugs for Therapy Against Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase 1 Levels

HPV infection and EGFR activation/alteration in HIV-infected East African patients with conjunctival carcinoma

MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model

Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed-Platinum-Radiation in Patients with Advanced Nonsquamous Non-Small Cell Lung Cancer: Results of a Phase I Trial

Computational Drug Repositioning Identifies Statins as Modifiers of Prognostic Genetic Expression Signatures and Metastatic Behavior in Melanoma

Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers

Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors

Abstract 2816: Evaluation of Cdk5 inhibitors in neural crest tumors

Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors

μ-Calpain Activation in β-Lapachone-Mediated Apoptosis

From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation

The C-terminus of interferon gamma receptor beta chain (IFNγR2) has antiapoptotic activity as a bax inhibitor

Identification of a Class of Novel Tubulin Inhibitors

Nuclear Clusterin/XIP8, an X-Ray-Induced Ku70-Binding Protein That Signals Cell Death

Interactions between self-assembled polyelectrolyte shells and tumor cells

Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines

Mornings with art, lessons learned: Feedback regulation, restriction threshold biology, and redundancy govern molecular stress responses

Computational drug repositioning identifies statins as a modifier of prognostic genetic expression signatures and metastatic behavior in melanoma

Adding Base Excision Repair Inhibitor TRC102 to standard Pemetrexed-Platinum-Radiation in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Results of a phase I trial

An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein

Delayed apoptotic responses associated with radiation-induced neoplastic transformation of human hybrid cells

HEXIM1 is a critical determinant of the response to tamoxifen

NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

Calcium Is a Key Signaling Molecule in β-Lapachone-mediated Cell Death

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