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Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization

Frontiers in immunology, 2022-06, Vol.13, p.877930-877930

2022

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Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes

Blood, 2010-09, Vol.116 (11), p.1895-1898

2010

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The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells

The Journal of experimental medicine, 2013-07, Vol.210 (8), p.1501-1507

2013

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Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Nature (London), 2003-04, Vol.422 (6933), p.726-730

2003

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Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry

Cell, 2017-04, Vol.169 (3), p.523-537.e15

2017

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AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.931-934

2012

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The IgH Eµ -MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation

Frontiers in immunology, 2023, Vol.14, p.1030813-1030813

2023

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Elucidation of IgH Intronic Enhancer Functions via Germ-Line Deletion

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (40), p.14362-14367

2005

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Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (6), p.1618-1623

2016

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Enhancers Located in Heavy Chain Regulatory Region (hs3a, hs1,2, hs3b, and hs4) Are Dispensable for Diversity of VDJ Recombination

The Journal of biological chemistry, 2012-03, Vol.287 (11), p.8356-8360

2012

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In Vivo Redundant Function of the 3' IgH Regulatory Element HS3b in the Mouse

The Journal of immunology (1950), 2010-04, Vol.184 (7), p.3710-3717

2010

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Fam72a enforces error-prone DNA repair during antibody diversification

Nature (London), 2021-12, Vol.600 (7888), p.329-333

2021

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A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

Cellular & molecular immunology, 2023-10, Vol.20 (10), p.1114-1126

2023

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S-S Synapsis during Class Switch Recombination Is Promoted by Distantly Located Transcriptional Elements and Activation-Induced Deaminase

Immunity (Cambridge, Mass.), 2007-11, Vol.27 (5), p.711-722

2007

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The IgH Locus 3' Regulatory Region: Pulling the Strings from Behind

Advances in Immunology, 2011, Vol.110, p.27-70

2011

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Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method

The Journal of immunology (1950), 2018-08, Vol.201 (3), p.950-956

2018

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Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region

Nature (London), 2009-12, Vol.462 (7274), p.803-807

2009

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The IgH 3′ regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate

Oncotarget, 2015-03, Vol.6 (7), p.4845-4852

2015

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The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo

The Journal of immunology (1950), 2014-08, Vol.193 (3), p.1171-1183

2014

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The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

Oncotarget, 2017-02, Vol.8 (8), p.12929-12940

2017

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E μ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

Scientific reports, 2017-03, Vol.7 (1), p.442-442

2017

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Deletion of the [alpha] immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion

Immunology, 2012-05, Vol.136 (1), p.54

2012

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Nuclear Proximity of Mtr4 with RNA exosome restricts DNA mutational asymmetry

Cell, 2017-04, Vol.169 (3), p.523-537.e15

2017

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Panorama of stepwise involvement of the IgH 3' regulatory region in murine B cells

Advances in immunology, 2021, Vol.149, p.95-114

2021

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Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination

Immunity (Cambridge, Mass.), 2001-08, Vol.15 (2), p.187-199

2001

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Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization

Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry

AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells

The IgH Eµ -MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation

Elucidation of IgH Intronic Enhancer Functions via Germ-Line Deletion

Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region

Enhancers Located in Heavy Chain Regulatory Region (hs3a, hs1,2, hs3b, and hs4) Are Dispensable for Diversity of VDJ Recombination

In Vivo Redundant Function of the 3' IgH Regulatory Element HS3b in the Mouse

Fam72a enforces error-prone DNA repair during antibody diversification

A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

S-S Synapsis during Class Switch Recombination Is Promoted by Distantly Located Transcriptional Elements and Activation-Induced Deaminase

The IgH Locus 3' Regulatory Region: Pulling the Strings from Behind

Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region

The IgH 3′ regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate

The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo

The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

E μ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

Deletion of the [alpha] immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion

Nuclear Proximity of Mtr4 with RNA exosome restricts DNA mutational asymmetry

Panorama of stepwise involvement of the IgH 3' regulatory region in murine B cells

Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination

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