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Toward Project Optimus for Oncology Precision Medicine: Multi‐Dimensional Dose Optimization Enabled by Quantitative Clinical Pharmacology

Clinical pharmacology and therapeutics, 2022-11, Vol.112 (5), p.927-932

2022

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Weaning off Thorough QT Studies

Clinical pharmacology and therapeutics, 2024-07, Vol.116 (1), p.11-13

2024

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Model‐Informed Drug Development: Connecting the Dots With a Totality of Evidence Mindset to Advance Therapeutics

Clinical pharmacology and therapeutics, 2021-11, Vol.110 (5), p.1147-1154

2021

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Probability of Success in Drug Development

Clinical pharmacology and therapeutics, 2022-05, Vol.111 (5), p.983-985

Graaf, Piet H.

2022

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Clinical Significance of Therapeutic Peptide and Protein Drug Interactions: A Call to Action

Clinical pharmacology and therapeutics, 2023-06, Vol.113 (6), p.1173-1174

Graaf, Piet H.

2023

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Mush Room for Improving Therapeutic Approaches in Psychiatry

Clinical pharmacology and therapeutics, 2023-04, Vol.113 (4), p.757-759

Graaf, Piet H.

2023

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Reflections on Model‐Informed Drug Development

Clinical pharmacology and therapeutics, 2024-08, Vol.116 (2), p.267-270

2024

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Diversity in Clinical Pharmacology Coming of Age

Clinical pharmacology and therapeutics, 2022-08, Vol.112 (2), p.191-193

Graaf, Piet H.

2022

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The Pandemic as a Catalyst for Disruptive Innovation in Clinical Pharmacology

Clinical pharmacology and therapeutics, 2022-03, Vol.111 (3), p.529-532

2022

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Diversity in Clinical Pharmacology and Therapeutics

Clinical pharmacology and therapeutics, 2021-10, Vol.110 (4), p.837-840

Graaf, Piet H.

2021

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Learn–confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform

CPT: pharmacometrics and systems pharmacology, 2023-02, Vol.12 (2), p.139-143

2023

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Moving the needle for oncology dose optimization: A call for action

CPT: pharmacometrics and systems pharmacology, 2024-06, Vol.13 (6), p.909-918

2024

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Application of quantitative systems pharmacology to guide the optimal dosing of COVID‐19 vaccines

CPT: pharmacometrics and systems pharmacology, 2021-10, Vol.10 (10), p.1130-1133

2021

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Design principles of collateral sensitivity-based dosing strategies

Nature communications, 2021-09, Vol.12 (1), p.5691-14, Article 5691

2021

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Using a Network-Based Analysis Approach to Investigate the Involvement of S. aureus in the Pathogenesis of Granulomatosis with Polyangiitis

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1822

2023

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Toward Replacement of Thorough QT Studies

Clinical pharmacology and therapeutics, 2021-02, Vol.109 (2), p.281-282

Graaf, Piet H.

2021

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Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine

Clinical pharmacology and therapeutics, 2024-09, Vol.116 (3), p.491-496

2024

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How a Pandemic Simultaneously Strengthened Existing Fundamentals and Drove New Innovations in Clinical Pharmacology

Clinical pharmacology and therapeutics, 2022-12, Vol.112 (6), p.1141-1144

2022

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Data Science in Clinical Pharmacology and Drug Development for Improving Health Outcomes in Patients

Clinical pharmacology and therapeutics, 2020-04, Vol.107 (4), p.683-686

2020

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Best Practices for Pharmacokinetic Studies of New Chemical Entities

Clinical pharmacology and therapeutics, 2024-05, Vol.115 (5), p.917-919

2024

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The Pharmacological War Against and With Opioids

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.557-559

Graaf, Piet H.

2021

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Artificial Intelligence/Machine Learning: The New Frontier of Clinical Pharmacology and Precision Medicine

Clinical pharmacology and therapeutics, 2024-04, Vol.115 (4), p.637-642

2024

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The Role of Quantitative Systems Pharmacology in the Design of First‐in‐Human Trials

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.797-797

2018

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Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology

Clinical pharmacology and therapeutics, 2020-09, Vol.108 (3), p.528-541

2020

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Subcutaneous Biologics: Clinical Pharmacology and Drug Development

Clinical pharmacology and therapeutics, 2024-03, Vol.115 (3), p.385-390

2024

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Toward Project Optimus for Oncology Precision Medicine: Multi‐Dimensional Dose Optimization Enabled by Quantitative Clinical Pharmacology

Weaning off Thorough QT Studies

Model‐Informed Drug Development: Connecting the Dots With a Totality of Evidence Mindset to Advance Therapeutics

Probability of Success in Drug Development

Clinical Significance of Therapeutic Peptide and Protein Drug Interactions: A Call to Action

Mush Room for Improving Therapeutic Approaches in Psychiatry

Reflections on Model‐Informed Drug Development

Diversity in Clinical Pharmacology Coming of Age

The Pandemic as a Catalyst for Disruptive Innovation in Clinical Pharmacology

Diversity in Clinical Pharmacology and Therapeutics

Learn–confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform

Moving the needle for oncology dose optimization: A call for action

Application of quantitative systems pharmacology to guide the optimal dosing of COVID‐19 vaccines

Design principles of collateral sensitivity-based dosing strategies

Using a Network-Based Analysis Approach to Investigate the Involvement of S. aureus in the Pathogenesis of Granulomatosis with Polyangiitis

Toward Replacement of Thorough QT Studies

Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine

How a Pandemic Simultaneously Strengthened Existing Fundamentals and Drove New Innovations in Clinical Pharmacology

Data Science in Clinical Pharmacology and Drug Development for Improving Health Outcomes in Patients

Best Practices for Pharmacokinetic Studies of New Chemical Entities

The Pharmacological War Against and With Opioids

Artificial Intelligence/Machine Learning: The New Frontier of Clinical Pharmacology and Precision Medicine

The Role of Quantitative Systems Pharmacology in the Design of First‐in‐Human Trials

Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology

Subcutaneous Biologics: Clinical Pharmacology and Drug Development

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