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Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

American journal of epidemiology, 2013-10, Vol.178 (7), p.1177-1184

2013

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Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

International journal of epidemiology, 2011-06, Vol.40 (3), p.740-752

2011

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Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank

The journals of gerontology. Series A, Biological sciences and medical sciences, 2021-01, Vol.76 (1), p.15-22

2021

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Sequencing-based fine-mapping and in silico functional characterization of the 10q24.32 arsenic metabolism efficiency locus across multiple arsenic-exposed populations

PLoS genetics, 2023-01, Vol.19 (1), p.e1010588

2023

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DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits

Nature genetics, 2023-01, Vol.55 (1), p.112-122

2023

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Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Genome Biology, 2020-09, Vol.21 (1), p.236-236, Article 236

2020

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Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study

The Lancet (British edition), 2010-07, Vol.376 (9737), p.252-258

2010

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Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

PLoS genetics, 2014-12, Vol.10 (12), p.e1004818-e1004818

2014

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Why are diabetics at reduced risk for prostate cancer? A review of the epidemiologic evidence

Urologic oncology, 2012-09, Vol.30 (5), p.735-743

Pierce, Brandon L., Ph.D

2012

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Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh

PLoS genetics, 2012-02, Vol.8 (2), p.e1002522

2012

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Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients

Journal of clinical oncology, 2009-07, Vol.27 (21), p.3437-3444

2009

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Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study

Neurobiology of aging, 2014-06, Vol.35 (6), p.1512.e11-1512.e18

2014

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An integrative multi-context Mendelian randomization method for identifying risk genes across human tissues

American journal of human genetics, 2024-08, Vol.111 (8), p.1736-1749

2024

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Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer

PLoS genetics, 2017-09, Vol.13 (9), p.e1006727-e1006727

2017

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Genome-Wide Pleiotropy Scan Identifies HNF1A Region as a Novel Pancreatic Cancer Susceptibility Locus

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (13), p.4352-4358

2011

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Nature communications, 2018-06, Vol.9 (1), p.2282-12, Article 2282

2018

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A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh

PLoS genetics, 2019-03, Vol.15 (3), p.e1007984

2019

Volltextzugriff (PDF)

Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms

Nature communications, 2018-02, Vol.9 (1), p.804-12, Article 804

2018

Volltextzugriff (PDF)

The aging epigenome

eLife, 2022-04, Vol.11

Pierce, Brandon L

2022

Volltextzugriff (PDF)

Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated With Reduced AS3MT Expression in Multiple Human Tissue Types

Toxicological sciences, 2020-08, Vol.176 (2), p.382-395

2020

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Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study

BMJ (Online), 2017-10, Vol.359, p.j4761

2017

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Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts

Nature communications, 2023-03, Vol.14 (1), p.1489-1489, Article 1489

2023

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Lessons Learned From Past Gene-Environment Interaction Successes

American journal of epidemiology, 2017-10, Vol.186 (7), p.778-786

2017

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Sex-Specific and Time-Varying Associations Between Cigarette Smoking and Telomere Length Among Older Adults

American journal of epidemiology, 2016-12, Vol.184 (12), p.922-932

2016

Volltextzugriff (PDF)

CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression

Bioinformatics (Oxford, England), 2021-09, Vol.37 (17), p.2513-2520

2021

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Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank

Sequencing-based fine-mapping and in silico functional characterization of the 10q24.32 arsenic metabolism efficiency locus across multiple arsenic-exposed populations

DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits

Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study

Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

Why are diabetics at reduced risk for prostate cancer? A review of the epidemiologic evidence

Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh

Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients

Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study

An integrative multi-context Mendelian randomization method for identifying risk genes across human tissues

Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer

Genome-Wide Pleiotropy Scan Identifies HNF1A Region as a Novel Pancreatic Cancer Susceptibility Locus

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh

Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms

The aging epigenome

Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated With Reduced AS3MT Expression in Multiple Human Tissue Types

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study

Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts

Lessons Learned From Past Gene-Environment Interaction Successes

Sex-Specific and Time-Varying Associations Between Cigarette Smoking and Telomere Length Among Older Adults

CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression

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