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Modeling conjugate vaccine and natural induced antibody correlates of protection for pneumococcal colonization and acute otitis media infection in young children

Vaccine, 2024-12, Vol.42 (26), p.126295, Article 126295

2024

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Anticipated Effects of Higher-valency Pneumococcal Conjugate Vaccines on Colonization and Acute Otitis Media

The Pediatric infectious disease journal, 2024-10, Vol.43 (10), p.1004-1010

2024

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Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

Clinical epigenetics, 2024-07, Vol.16 (1), p.85-10, Article 85

2024

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Variability of Vaccine Responsiveness in Young Children

The Journal of infectious diseases, 2024-06, Vol.229 (6), p.1856

2024

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Pneumococci isolated from children in community-based practice differ from isolates identified by population and laboratory-based invasive disease surveillance

The Journal of infectious diseases, 2024-04

2024

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Serotype 3 Antibody Response and Antibody Functionality Compared to Serotype 19A Following 13-Valent Pneumococcal Conjugate Immunization in Children

The Pediatric infectious disease journal, 2024-03, Vol.43 (3), p.294-300

2024

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Acute otitis media pneumococcal disease burden and nasopharyngeal colonization in children due to serotypes included and not included in current and new pneumococcal conjugate vaccines

Expert review of vaccines, 2023-12, Vol.22 (1), p.118-138

2023

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1725. Differences in serotype 3 antibody response and antibody functionality compared to serotype 19A following 13-valent pneumococcal conjugate immunization in children

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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1688. Naturally-induced Serum Antibody Levels in Children to Pneumococcal Polysaccharide 15B that Correlate with Protection from Nasopharyngeal Colonization but Anti-serotype 15B Antibody has Low Functional Cross-reactivity with Serotype 15C

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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Naturally-induced serum antibody levels in children to pneumococcal polysaccharide 15B that correlate with protection from nasopharyngeal colonization but anti-serotype 15B antibody has low functional cross-reactivity with serotype 15C

Vaccine, 2023-11, Vol.41 (48), p.7265-7273

2023

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Variability of vaccine responsiveness in early life

Cellular immunology, 2023-11, Vol.393-394, p.104777-104777, Article 104777

Pichichero, Michael E

2023

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Very early life microbiome and metabolome correlates with primary vaccination variability in children

mSystems, 2023-10, Vol.8 (5), p.e0066123-e0066123

2023

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Expression conditions and characterization of a novelly constructed lipoprotein intended as a vaccine to prevent human Haemophilus influenzae infections

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.105031-105031, Article 105031

2023

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Colonization, Density, and Antibiotic Resistance of Streptococcus pneumoniae, Haemophilus Influenzae, and Moraxella catarrhalis among PCV13-Vaccinated Infants in the First Six Months of Life in Rochester, New York: A Cohort Study

Journal of the Pediatric Infectious Diseases Society, 2023-04, Vol.12 (3), p.135-142

2023

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Window of Susceptibility to Acute Otitis Media Infection

Pediatrics (Evanston), 2023-02, Vol.151 (2), p.1

2023

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Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers

Proteins, structure, function, and bioinformatics, 2023-02, Vol.91 (2), p.161-170

2023

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Abstract 1658: Haemophilus influenzae Protein D antibody suppression in a multi-component vaccine formulation

The Journal of biological chemistry, 2023, Vol.299 (3), p.104047, Article 104047

2023

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Haemophilus influenzae Protein D antibody suppression in a multi‐component vaccine formulation

FEBS open bio, 2022-12, Vol.12 (12), p.2191-2202

2022

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Pathogenesis of Streptococcus pneumoniae serotype 3 during natural colonization and infections among children and its IgG correlate of protection in a mouse model

Vaccine, 2022-10, Vol.40 (44), p.6412-6421

2022

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Lipidation of Haemophilus influenzae Antigens P6 and OMP26 Improves Immunogenicity and Protection against Nasopharyngeal Colonization and Ear Infection

Infection and immunity, 2022-05, Vol.90 (5), p.e0067821-e0067821

2022

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Antibiotic Use and Vaccine Antibody Levels

Pediatrics (Evanston), 2022-05, Vol.149 (5), p.1

2022

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Interferon-γ promotes monocyte-mediated lung injury during influenza infection

Cell reports (Cambridge), 2022-03, Vol.38 (9), p.110456-110456, Article 110456

2022

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Pneumonia, Sinusitis, Influenza and Other Respiratory Illnesses in Acute Otitis Media-Prone Children

The Pediatric infectious disease journal, 2021-11, Vol.40 (11), p.975-980

2021

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Transition of Serotype 35B Pneumococci From Commensal to Prevalent Virulent Strain in Children

Frontiers in cellular and infection microbiology, 2021-10, Vol.11, p.744742-744742

2021

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Nasopharyngeal microbiome composition associated with Streptococcus pneumoniae colonization suggests a protective role of Corynebacterium in young children

PloS one, 2021-09, Vol.16 (9), p.e0257207-e0257207

2021

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Modeling conjugate vaccine and natural induced antibody correlates of protection for pneumococcal colonization and acute otitis media infection in young children

Anticipated Effects of Higher-valency Pneumococcal Conjugate Vaccines on Colonization and Acute Otitis Media

Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

Variability of Vaccine Responsiveness in Young Children

Pneumococci isolated from children in community-based practice differ from isolates identified by population and laboratory-based invasive disease surveillance

Serotype 3 Antibody Response and Antibody Functionality Compared to Serotype 19A Following 13-Valent Pneumococcal Conjugate Immunization in Children

Acute otitis media pneumococcal disease burden and nasopharyngeal colonization in children due to serotypes included and not included in current and new pneumococcal conjugate vaccines

1725. Differences in serotype 3 antibody response and antibody functionality compared to serotype 19A following 13-valent pneumococcal conjugate immunization in children

1688. Naturally-induced Serum Antibody Levels in Children to Pneumococcal Polysaccharide 15B that Correlate with Protection from Nasopharyngeal Colonization but Anti-serotype 15B Antibody has Low Functional Cross-reactivity with Serotype 15C

Naturally-induced serum antibody levels in children to pneumococcal polysaccharide 15B that correlate with protection from nasopharyngeal colonization but anti-serotype 15B antibody has low functional cross-reactivity with serotype 15C

Variability of vaccine responsiveness in early life

Very early life microbiome and metabolome correlates with primary vaccination variability in children

Expression conditions and characterization of a novelly constructed lipoprotein intended as a vaccine to prevent human Haemophilus influenzae infections

Colonization, Density, and Antibiotic Resistance of Streptococcus pneumoniae, Haemophilus Influenzae, and Moraxella catarrhalis among PCV13-Vaccinated Infants in the First Six Months of Life in Rochester, New York: A Cohort Study

Window of Susceptibility to Acute Otitis Media Infection

Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers

Abstract 1658: Haemophilus influenzae Protein D antibody suppression in a multi-component vaccine formulation

Haemophilus influenzae Protein D antibody suppression in a multi‐component vaccine formulation

Pathogenesis of Streptococcus pneumoniae serotype 3 during natural colonization and infections among children and its IgG correlate of protection in a mouse model

Lipidation of Haemophilus influenzae Antigens P6 and OMP26 Improves Immunogenicity and Protection against Nasopharyngeal Colonization and Ear Infection

Antibiotic Use and Vaccine Antibody Levels

Interferon-γ promotes monocyte-mediated lung injury during influenza infection

Pneumonia, Sinusitis, Influenza and Other Respiratory Illnesses in Acute Otitis Media-Prone Children

Transition of Serotype 35B Pneumococci From Commensal to Prevalent Virulent Strain in Children

Nasopharyngeal microbiome composition associated with Streptococcus pneumoniae colonization suggests a protective role of Corynebacterium in young children

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