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Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

Science signaling, 2018-12, Vol.11 (559)

2018

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Membrane signalling complexes: Implications for development of functionally selective ligands modulating heptahelical receptor signalling

Cellular signalling, 2009-02, Vol.21 (2), p.179-185

Piñeyro, Graciela

2009

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Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action

Neuron (Cambridge, Mass.), 2007-09, Vol.55 (5), p.712-725

2007

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Regulation of opioid receptor signalling: implications for the development of analgesic tolerance

Molecular brain, 2011-06, Vol.4 (1), p.25-25

2011

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N‑Guanidyl and C‑Tetrazole Leu-Enkephalin Derivatives: Efficient Mu and Delta Opioid Receptor Agonists with Improved Pharmacological Properties

ACS chemical neuroscience, 2019-03, Vol.10 (3), p.1615-1626

2019

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β-Arrestin-Mediated Activation of MAPK by Inverse Agonists Reveals Distinct Active Conformations for G Protein-Coupled Receptors

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11406-11411

2003

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Ligand-specific receptor states: Implications for opiate receptor signalling and regulation

Cellular signalling, 2007, Vol.19 (1), p.8-19

2007

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Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression

Psychopharmacologia, 2009-08, Vol.205 (2), p.293-303

2009

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Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat

PloS one, 2010-02, Vol.5 (2), p.e9253

2010

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A type II cannabis extract and a 1:1 blend of Δ(9)-tetrahydrocannabinol and cannabidiol display distinct antinociceptive profiles and engage different endocannabinoid targets when administered into the subarachnoid space

Frontiers in pharmacology, 2023-09, Vol.14, p.1235255-1235255

2023

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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Nature communications, 2019-09, Vol.10 (1), p.4075-4075, Article 4075

2019

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Exploration of the fifth position of leu‐enkephalin and its role in binding and activating delta (DOP) and mu (MOP) opioid receptors

Peptide science (Hoboken, N.J.), 2019-01, Vol.111 (1), p.n/a

2019

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Kir3 channel signaling complexes: focus on opioid receptor signaling

Frontiers in cellular neuroscience, 2014-07, Vol.8, p.186-186

2014

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Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR

Scientific reports, 2020-05, Vol.10 (1), p.8779-8779, Article 8779

2020

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Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Nature communications, 2020-04, Vol.11 (1), p.1929-1929, Article 1929

2020

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379. Molecular Pathways Underpinning Cannabis-Related Variations in Cortical Thickness During Adolescence

Biological psychiatry (1969), 2023-05, Vol.93 (9), p.S247-S247

2023

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Autoregulation of serotonin neurons: role in antidepressant drug action

Pharmacological reviews, 1999-09, Vol.51 (3), p.533

1999

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Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias

Cellular signalling, 2021-04, Vol.80, p.109906-109906, Article 109906

2021

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Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence

The Journal of neuroscience, 2024-08, p.e2256232024

2024

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Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action

Neuron (Cambridge, Mass.), 2007-09, Vol.55 (5), p.712-725

2007

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Using BRET to detect ligand-specific conformational changes in preformed signalling complexes

Methods in molecular biology (Clifton, N.J.), 2011, Vol.756, p.149

2011

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Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach

Methods (San Diego, Calif.), 2016-01, Vol.92, p.78-86

2016

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Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice

Neuroreport, 1995-12, Vol.7 (1), p.353-359

1995

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Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories

Molecular psychiatry, 2023-07, Vol.28 (7), p.2946-2963

2023

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Molecular Pharmacology of δ-Opioid Receptors

Pharmacological reviews, 2016-07, Vol.68 (3), p.631-700

2016

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Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

Membrane signalling complexes: Implications for development of functionally selective ligands modulating heptahelical receptor signalling

Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action

Regulation of opioid receptor signalling: implications for the development of analgesic tolerance

N‑Guanidyl and C‑Tetrazole Leu-Enkephalin Derivatives: Efficient Mu and Delta Opioid Receptor Agonists with Improved Pharmacological Properties

β-Arrestin-Mediated Activation of MAPK by Inverse Agonists Reveals Distinct Active Conformations for G Protein-Coupled Receptors

Ligand-specific receptor states: Implications for opiate receptor signalling and regulation

Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression

Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat

A type II cannabis extract and a 1:1 blend of Δ(9)-tetrahydrocannabinol and cannabidiol display distinct antinociceptive profiles and engage different endocannabinoid targets when administered into the subarachnoid space

Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Exploration of the fifth position of leu‐enkephalin and its role in binding and activating delta (DOP) and mu (MOP) opioid receptors

Kir3 channel signaling complexes: focus on opioid receptor signaling

Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR

Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

379. Molecular Pathways Underpinning Cannabis-Related Variations in Cortical Thickness During Adolescence

Autoregulation of serotonin neurons: role in antidepressant drug action

Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias

Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence

Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action

Using BRET to detect ligand-specific conformational changes in preformed signalling complexes

Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach

Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice

Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories

Molecular Pharmacology of δ-Opioid Receptors

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