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Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species

PLoS genetics, 2022-07, Vol.18 (7), p.e1010215-e1010215

2022

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A rationale for tRNA modification circuits in the anticodon loop

RNA (Cambridge), 2018-10, Vol.24 (10), p.1277-1284

2018

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tRNA biology charges to the front

Genes & development, 2010-09, Vol.24 (17), p.1832-1860

2010

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Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences

PLoS genetics, 2020-08, Vol.16 (8), p.e1008893-e1008893

2020

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Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay path way in evolutionarily distant yeast species

PLoS genetics, 2022-07, Vol.18 (7), p.e1010215

2022

Volltextzugriff (PDF)

The life and times of a tRNA

RNA (Cambridge), 2023-07, Vol.29 (7), p.898-957

2023

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Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

PLoS genetics, 2018-03, Vol.14 (3), p.e1007288-e1007288

2018

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A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition

Human genetics, 2016-07, Vol.135 (7), p.707-713

2016

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Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation

Molecular systems biology, 2014-12, Vol.10 (12), p.770-n/a

2014

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S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates

RNA (Cambridge), 2017-03, Vol.23 (3), p.406-419

2017

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Do all modifications benefit all tRNAs?

FEBS letters, 2010-01, Vol.584 (2), p.265-271

2010

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Two-subunit enzymes involved in eukaryotic post-transcriptional tRNA modification

RNA biology, 2014-12, Vol.11 (12), p.1608-1618

2014

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Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

Genes & development, 2008-05, Vol.22 (10), p.1369-1380

2008

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Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1

Human mutation, 2015-12, Vol.36 (12), p.1176-1187

2015

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Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast

RNA (Cambridge), 2020-01, Vol.26 (1), p.29-43

2020

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Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability

Molecular and cellular biology, 2019-10, Vol.39 (19)

2019

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PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly

Human genetics, 2019-03, Vol.138 (3), p.231-239

2019

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A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay

PLoS genetics, 2024-01, Vol.20 (1), p.e1011146-e1011146

2024

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tRNAs Marked with CCACCA Are Targeted for Degradation

Science (American Association for the Advancement of Science), 2011-11, Vol.334 (6057), p.817-821

2011

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Rapid tRNA Decay Can Result from Lack of Nonessential Modifications

Molecular cell, 2006-01, Vol.21 (1), p.87-96

2006

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tRNA processing, modification, and subcellular dynamics: past, present, and future

RNA (Cambridge), 2015-04, Vol.21 (4), p.483-485

2015

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The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA

Genes & development, 2011-06, Vol.25 (11), p.1173-1184

2011

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A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop

RNA (Cambridge), 2011-06, Vol.17 (6), p.1100-1110

2011

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Conditional accumulation of toxic tRNAs to cause amino acid misincorporation

Nucleic acids research, 2018-09, Vol.46 (15), p.7831

2018

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The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications

RNA (Cambridge), 2012-10, Vol.18 (10), p.1886-1896

2012

Volltextzugriff (PDF)

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Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species

A rationale for tRNA modification circuits in the anticodon loop

tRNA biology charges to the front

Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences

Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay path way in evolutionarily distant yeast species

The life and times of a tRNA

Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition

Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation

S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates

Do all modifications benefit all tRNAs?

Two-subunit enzymes involved in eukaryotic post-transcriptional tRNA modification

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1

Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast

Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability

PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly

A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay

tRNAs Marked with CCACCA Are Targeted for Degradation

Rapid tRNA Decay Can Result from Lack of Nonessential Modifications

tRNA processing, modification, and subcellular dynamics: past, present, and future

The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA

A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop

Conditional accumulation of toxic tRNAs to cause amino acid misincorporation

The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications

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