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Inhaled Phosphodiesterase 4 (PDE4) Inhibitors for Inflammatory Respiratory Diseases

Frontiers in pharmacology, 2020-03, Vol.11, p.259-259

Phillips, Jonathan E

2020

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The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals

eLife, 2024-03, Vol.12

2024

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Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease

PloS one, 2013-04, Vol.8 (4), p.e59348

2013

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Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis

eLife, 2022-06, Vol.11

2022

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Assessment of Brd4 Inhibition in Idiopathic Pulmonary Fibrosis Lung Fibroblasts and in Vivo Models of Lung Fibrosis

The American journal of pathology, 2013-08, Vol.183 (2), p.470-479

2013

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secreted protein is an endogenous chemorepellant in Dictyostelium discoideum

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.10990-10995

2012

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Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Sensors (Basel, Switzerland), 2022-03, Vol.22 (6), p.2264

2022

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Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum

Disease models & mechanisms, 2015-02, Vol.8 (2), p.147-156

2015

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Assembling a Hippo: the evolutionary emergence of an animal developmental signaling pathway

Trends in biochemical sciences (Amsterdam. Regular ed.), 2024-08, Vol.49 (8), p.681-692

2024

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The p21-activated kinase (PAK) family member PakD is required for chemorepulsion and proliferation inhibition by autocrine signals in Dictyostelium discoideum

PloS one, 2014-05, Vol.9 (5), p.e96633-e96633

2014

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Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma

American journal of physiology. Lung cellular and molecular physiology, 2014-01, Vol.306 (2), p.L196-L206

2014

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The ROCO Kinase QkgA Is Necessary for Proliferation Inhibition by Autocrine Signals in Dictyostelium discoideum

Eukaryotic Cell, 2010-10, Vol.9 (10), p.1557-1565

2010

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House dust mite models: Will they translate clinically as a superior model of asthma?

Journal of allergy and clinical immunology, 2013-07, Vol.132 (1), p.242-244

2013

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A Retinoblastoma Orthologue Is Required for the Sensing of a Chalone in Dictyostelium discoideum

Eukaryotic Cell, 2014-03, Vol.13 (3), p.376-382

2014

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Practical Considerations in Dose Extrapolation from Animals to Humans

Journal of aerosol medicine and pulmonary drug delivery, 2024-04, Vol.37 (2), p.77-89

2024

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Association of bronchial disease on CT imaging and clinical definitions of chronic bronchitis in a single-center COPD phenotyping study

Respiratory medicine, 2024-09, Vol.231, p.107733, Article 107733

2024

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Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl‐peptidase IV

Protein science, 2017-03, Vol.26 (3), p.578-585

2017

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Development of a QPatch-Automated Electrophysiology Assay for Identifying TMEM16A Small-Molecule Inhibitors

Assay and drug development technologies, 2020-04, Vol.18 (3), p.134-147

2020

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Corrigendum to “Bleomycin induced lung fibrosis increases work of breathing in the mouse” [Pulm. Pharmacol.Therapeut. 25 (2012) 281-285]

Pulmonary pharmacology & therapeutics, 2022-06, Vol.73-74, p.102122-102122, Article 102122

2022

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Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Journal of visualized experiments, 2017-04 (122)

2017

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The Putative bZIP Transcripton Factor BzpN Slows Proliferation and Functions in the Regulation of Cell Density by Autocrine Signals in Dictyostelium

PloS one, 2011-07, Vol.6 (7), p.e21765

2011

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Regulation of vocal fold transepithelial water fluxes

Journal of applied physiology (1985), 2001-09, Vol.91 (3), p.1401-1411

2001

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Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma

Journal of aerosol medicine and pulmonary drug delivery, 2016-06, Vol.29 (3), p.233-241

2016

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Bleomycin induced lung fibrosis increases work of breathing in the mouse

Pulmonary pharmacology & therapeutics, 2012-08, Vol.25 (4), p.281-285

2012

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Tachykinin NK 3 and NK 1 receptor activation elicits secretion from porcine airway submucosal glands

British journal of pharmacology, 2009-02, Vol.138 (1), p.254-260

2009

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Inhaled Phosphodiesterase 4 (PDE4) Inhibitors for Inflammatory Respiratory Diseases

The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals

Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease

Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis

Assessment of Brd4 Inhibition in Idiopathic Pulmonary Fibrosis Lung Fibroblasts and in Vivo Models of Lung Fibrosis

secreted protein is an endogenous chemorepellant in Dictyostelium discoideum

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum

Assembling a Hippo: the evolutionary emergence of an animal developmental signaling pathway

The p21-activated kinase (PAK) family member PakD is required for chemorepulsion and proliferation inhibition by autocrine signals in Dictyostelium discoideum

Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma

The ROCO Kinase QkgA Is Necessary for Proliferation Inhibition by Autocrine Signals in Dictyostelium discoideum

House dust mite models: Will they translate clinically as a superior model of asthma?

A Retinoblastoma Orthologue Is Required for the Sensing of a Chalone in Dictyostelium discoideum

Practical Considerations in Dose Extrapolation from Animals to Humans

Association of bronchial disease on CT imaging and clinical definitions of chronic bronchitis in a single-center COPD phenotyping study

Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl‐peptidase IV

Development of a QPatch-Automated Electrophysiology Assay for Identifying TMEM16A Small-Molecule Inhibitors

Corrigendum to “Bleomycin induced lung fibrosis increases work of breathing in the mouse” [Pulm. Pharmacol.Therapeut. 25 (2012) 281-285]

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

The Putative bZIP Transcripton Factor BzpN Slows Proliferation and Functions in the Regulation of Cell Density by Autocrine Signals in Dictyostelium

Regulation of vocal fold transepithelial water fluxes

Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma

Bleomycin induced lung fibrosis increases work of breathing in the mouse

Tachykinin NK 3 and NK 1 receptor activation elicits secretion from porcine airway submucosal glands

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