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Abstract 5115: Pre-clinical development of next generation inhibitors of the enzymes indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase as cancer immunotherapies

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.5115-5115

2016

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ITOC2 – 013. In vitro kynurenine modulation by novel dual-acting and selective TDO and IDO inhibitors

European journal of cancer (1990), 2015-03, Vol.51, p.S5-S5

2015

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The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.497-501

2011

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Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB₁ antagonists

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2034-2039

2011

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Abstract B055: Characterization of highly selective and CNS-penetrant PARP1 inhibitors

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.B055-B055

2023

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Abstract 6172: Characterization of a novel series of highly selective PARP1 inhibitors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6172-6172

2023

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Abstract 486: Characterization of a novel series of highly selective PARP7 inhibitors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.486-486

2023

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Abstract 7120: Investigating PARP1 selective inhibitor DSB1559 efficacy in BRCA1-associated triple negative breast cancer

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.7120-7120

2024

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Abstract LB-B14: Characterization of next generation IDO1 and TDO inhibitors as novel cancer immunotherapeutic agents

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.LB-B14-LB-B14

2015

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Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.589-593

2005

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Abstract 4292: In vitro kynurenine modulation by novel dual-acting and selective tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) inhibitors

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4292-4292

2015

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Abstract 1283: Identification and activity of novel GLUT1 inhibitors in hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1283-1283

2016

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Recent Progress in Cannabinoid Research

Progress in Medicinal Chemistry, 2006, Vol.44, p.207-329

2006

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Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB sub(1 antagonists)

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2034-2039

2011

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Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB 1 antagonists

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (7), p.2034-2039

2011

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Asymmetric synthesis of (3S)-2,3,4,5-tetrahydropyridazine-3-carboxylic acid

Journal of the Chemical Society. Chemical communications, 1993 (15), p.1179-1180

1993

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Trends in medicinal chemistry 2004

Drug News & Perspectives, 2005-03, Vol.18 (2), p.142-148

2005

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Applications of Solid-Phase Synthesis to Drug Discovery

Current medicinal chemistry, 1997-06, Vol.4 (3), p.211-227

1997

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The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.497-501

2011

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Regio- and stereo-selective intermolecular interceptions of a conjugated N-acylhydrazonium ion

Tetrahedron letters, 1994-10, Vol.35 (42), p.7853-7856

1994

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6 Recent Progress in Cannabinoid Research

Progress in Medicinal Chemistry, 2006, Vol.44, p.207-329

2006

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Enhanced discrimination by aza dienophiles over their olefinic counterparts for the diastereotopic faces of methyl ( E, E)-5-(2′,3′,4′,6′-tetra- O-acetyl-β- d-glucopyranosyloxy)penta-2,4-dienoate

Tetrahedron letters, 1994-05, Vol.35 (20), p.3397-3400

1994

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Asymmetric synthesis of (3S )-2,3,4,5-tetrahydropyridazine-3-carboxylic acid and its methyl ester

Journal of the Chemical Society, Perkin Transactions 1, 1999 (18), p.2591-2600

1999

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Asymmetric Synthesis of α-Amino Acids

Cowley, Phillip M

1993

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Asymmetric Synthesis of α-Amino Acids

Cowley, Phillip M

1993

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Abstract 5115: Pre-clinical development of next generation inhibitors of the enzymes indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase as cancer immunotherapies

ITOC2 – 013. In vitro kynurenine modulation by novel dual-acting and selective TDO and IDO inhibitors

The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonists

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB₁ antagonists

Abstract B055: Characterization of highly selective and CNS-penetrant PARP1 inhibitors

Abstract 6172: Characterization of a novel series of highly selective PARP1 inhibitors

Abstract 486: Characterization of a novel series of highly selective PARP7 inhibitors

Abstract 7120: Investigating PARP1 selective inhibitor DSB1559 efficacy in BRCA1-associated triple negative breast cancer

Abstract LB-B14: Characterization of next generation IDO1 and TDO inhibitors as novel cancer immunotherapeutic agents

Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists

Abstract 4292: In vitro kynurenine modulation by novel dual-acting and selective tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) inhibitors

Abstract 1283: Identification and activity of novel GLUT1 inhibitors in hepatocellular carcinoma

Recent Progress in Cannabinoid Research

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB sub(1 antagonists)

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB 1 antagonists

Asymmetric synthesis of (3S)-2,3,4,5-tetrahydropyridazine-3-carboxylic acid

Trends in medicinal chemistry 2004

Applications of Solid-Phase Synthesis to Drug Discovery

The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists

Regio- and stereo-selective intermolecular interceptions of a conjugated N-acylhydrazonium ion

6 Recent Progress in Cannabinoid Research

Enhanced discrimination by aza dienophiles over their olefinic counterparts for the diastereotopic faces of methyl ( E, E)-5-(2′,3′,4′,6′-tetra- O-acetyl-β- d-glucopyranosyloxy)penta-2,4-dienoate

Asymmetric synthesis of (3S )-2,3,4,5-tetrahydropyridazine-3-carboxylic acid and its methyl ester

Asymmetric Synthesis of α-Amino Acids

Asymmetric Synthesis of α-Amino Acids

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