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Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity

Protein science, 1998-10, Vol.7 (10), p.2118-2126

1998

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Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue

Cancer research (Chicago, Ill.), 1992-09, Vol.52 (18), p.4904

1992

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Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-α receptors in a human colon adenocarcinoma (Colo 205) cell line

Cancer research (Chicago, Ill.), 1998-09, Vol.58 (17), p.4001-4007

1998

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Solution structures of stromelysin complexed to thiadiazole inhibitors

Protein science, 1998-11, Vol.7 (11), p.2281-2286

1998

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Lethality, DNA alkylation, and cell cycle effects of adozelesin (U-73975) on rodent and human cells

Cancer research (Chicago, Ill.), 1992-10, Vol.52 (20), p.5687-5692

1992

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Reaction of the Antitumor Antibiotic CC-1065 with DNA: Structure of a DNA Adduct with DNA Sequence Specificity

Science (American Association for the Advancement of Science), 1984-11, Vol.226 (4676), p.843-844

1984

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Synthesis and DNA cross-linking by a rigid CPI dimer

Journal of the American Chemical Society, 1991-11, Vol.113 (23), p.8994-8995

1991

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Dopamine-Sensitive Adenylate Cyclase in Caudate Nucleus of Rat Brain, and Its Similarity to the ``Dopamine Receptor

Proceedings of the National Academy of Sciences - PNAS, 1972-08, Vol.69 (8), p.2145-2149

1972

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CHARACTERIZATION OF A DOPAMINE‐SENSITIVE ADENYLATE CYCLASE IN THE RAT CAUDATE NUCLEUS

Journal of neurochemistry, 1975-08, Vol.25 (2), p.143-149

1975

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Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

Proceedings of the National Academy of Sciences - PNAS, 1974-04, Vol.71 (4), p.1113-1117

1974

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Characterization of B16 melanoma cells resistant to the CC-1065 analogue U-71,184

Cancer research (Chicago, Ill.), 1990-04, Vol.50 (8), p.2485-2492

1990

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The binding of CC-1065 to thymidine and deoxyadenosine oligonucleotides and to poly(dA) · poly(dT)

Chemico-biological interactions, 1986-07, Vol.59 (1), p.55-72

1986

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A Fluorescence Resonance Energy Transfer Method for Measuring the Binding of Inhibitors to Stromelysin

Analytical biochemistry, 1999-11, Vol.275 (2), p.141-147

1999

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Evaluation of DNA binding characteristics of some CC-1065 analogs

Chemico-biological interactions, 1988, Vol.67 (3), p.199-213

1988

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Genotoxicity of the antitumor antibiotic CC-1065

Mutagenesis, 1986-11, Vol.1 (6), p.407-410

1986

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The constituent tryptophans and bisANS as fluorescent probes of the active site and of a secondary binding site of stromelysin-1 (MMP-3)

Journal of Protein Chemistry, 1998-10, Vol.17 (7), p.699-712

1998

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The Biosynthesis of Cytidine Diphosphate Diglyceride by Embryonic Chick Brain

The Journal of biological chemistry, 1967-03, Vol.242 (6), p.1187-1191

1967

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In vitro DNA damage/alkaline elution assay for predicting carcinogenic potential

Biochemical and biophysical research communications, 1976-09, Vol.72 (2), p.732-738

1976

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Mechanism of interaction of CC-1065 (NSC 298223) with DNA

Cancer research (Chicago, Ill.), 1982-07, Vol.42 (7), p.2821-2828

1982

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The binding of 1-(2-hydroxyethyl)-1-nitrosourea to DNA in vitro and to DNA of thymus and marrow in C57BL mice in vivo

Cancer letters, 1986-10, Vol.33 (1), p.75-81

1986

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Dissociation and Activation of Adenosine 3′,5′-Monophosphate-dependent and Guanosine 3′,5′-Monophosphate-dependent Protein Kinases by Cyclic Nucleotides and by Substrate Proteins

The Journal of biological chemistry, 1973-01, Vol.248 (1), p.179-189

1973

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Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver

Science (American Association for the Advancement of Science), 1970-04, Vol.168 (3929), p.382-384

1970

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Dissociation and concomitant activation of adenosine 3′,5′-monophosphate-dependent protein kinase by histone

Biochemical and biophysical research communications, 1971-07, Vol.44 (2), p.305-312

1971

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Dynamics of stromelysin/inhibitor interactions studied by 15N NMR relaxation measurements: comparison of ligand binding to the S1-S3 and S'1-S'3 subsites

Journal of biomolecular NMR, 1999-09, Vol.15 (1), p.55-64

1999

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Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity

Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue

Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-α receptors in a human colon adenocarcinoma (Colo 205) cell line

Solution structures of stromelysin complexed to thiadiazole inhibitors

Lethality, DNA alkylation, and cell cycle effects of adozelesin (U-73975) on rodent and human cells

Reaction of the Antitumor Antibiotic CC-1065 with DNA: Structure of a DNA Adduct with DNA Sequence Specificity

Synthesis and DNA cross-linking by a rigid CPI dimer

Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors

Dopamine-Sensitive Adenylate Cyclase in Caudate Nucleus of Rat Brain, and Its Similarity to the ``Dopamine Receptor

CHARACTERIZATION OF A DOPAMINE‐SENSITIVE ADENYLATE CYCLASE IN THE RAT CAUDATE NUCLEUS

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

Characterization of B16 melanoma cells resistant to the CC-1065 analogue U-71,184

The binding of CC-1065 to thymidine and deoxyadenosine oligonucleotides and to poly(dA) · poly(dT)

A Fluorescence Resonance Energy Transfer Method for Measuring the Binding of Inhibitors to Stromelysin

Evaluation of DNA binding characteristics of some CC-1065 analogs

Genotoxicity of the antitumor antibiotic CC-1065

The constituent tryptophans and bisANS as fluorescent probes of the active site and of a secondary binding site of stromelysin-1 (MMP-3)

The Biosynthesis of Cytidine Diphosphate Diglyceride by Embryonic Chick Brain

In vitro DNA damage/alkaline elution assay for predicting carcinogenic potential

Mechanism of interaction of CC-1065 (NSC 298223) with DNA

The binding of 1-(2-hydroxyethyl)-1-nitrosourea to DNA in vitro and to DNA of thymus and marrow in C57BL mice in vivo

Dissociation and Activation of Adenosine 3′,5′-Monophosphate-dependent and Guanosine 3′,5′-Monophosphate-dependent Protein Kinases by Cyclic Nucleotides and by Substrate Proteins

Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver

Dissociation and concomitant activation of adenosine 3′,5′-monophosphate-dependent protein kinase by histone

Dynamics of stromelysin/inhibitor interactions studied by 15N NMR relaxation measurements: comparison of ligand binding to the S1-S3 and S'1-S'3 subsites

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