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The roles of the prostaglandin D 2 receptors DP 1 and CRTH2 in promoting allergic responses

British journal of pharmacology, 2009-01, Vol.153 (S1)

Pettipher, R

2009

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Anti‐eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

Allergy (Copenhagen), 2013-03, Vol.68 (3), p.375-385

2013

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Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459

Allergy (Copenhagen), 2014-09, Vol.69 (9), p.1223-1232

2014

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A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

Clinical and experimental allergy, 2012-01, Vol.42 (1), p.38-48

2012

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The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

Allergy (Copenhagen), 2012-12, Vol.67 (12), p.1572-1579

2012

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The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses

British journal of pharmacology, 2008-03, Vol.153 (S1), p.S191-S199

Pettipher, R

2008

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Interaction between prostaglandin D₂ and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells

Clinical and experimental immunology, 2009-04, Vol.156 (1), p.126-133

2009

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CRTH2 mediates the activation of human Th2 cells in response to PGD(2) released from IgE/anti-IgE treated nasal polyp tissue

Allergy (Copenhagen), 2010-03, Vol.65 (3), p.304-310

2010

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CRTH2 mediates the activation of human Th2 cells in response to PGD₂ released from IgE/anti-IgE treated nasal polyp tissue

Allergy (Copenhagen), 2010-03, Vol.65 (3), p.304-310

2010

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Systemic administration of the chemokine macrophage inflammatory protein 1α exacerbates inflammatory bowel disease in a mouse model

Gut, 2005-08, Vol.54 (8), p.1114-1120

2005

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Interleukin 1 Induces Leukocyte Infiltration and Cartilage Proteoglycan Degradation in the Synovial Joint

Proceedings of the National Academy of Sciences - PNAS, 1986-11, Vol.83 (22), p.8749-8753

1986

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The roles of the prostaglandin D sub(2) receptors DP sub(1) and CRTH2 in promoting allergic responses

British journal of pharmacology, 2008-03, Vol.153, p.S191-S199

Pettipher, R

2008

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The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses

British journal of pharmacology, 2008-03, Vol.153 Suppl 1, p.S191

Pettipher, R

2008

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The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses: Life Sciences Supplement: A selection of review articles from the 2007 Life Sciences meeting in Glasgow

British journal of pharmacology, 2008, Vol.153

PETTIPHER, R

2008

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Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis

Proceedings of the National Academy of Sciences - PNAS, 1995-01, Vol.92 (2), p.517-521

1995

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Striking Effect of Hydroxamic Acid Substitution on the Phosphodiesterase Type 4 (PDE4) and TNFα Inhibitory Activity of Two Series of Rolipram Analogues: Implications for a New Active Site Model of PDE4

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.266-270

1998

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Arthritogenic actions of recombinant IL-1 and tumour necrosis factor α in the rabbit: evidence for synergistic interactions between cytokines in vivo

Clinical and experimental immunology, 1989-02, Vol.75 (2), p.306-310

1989

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2‐Amino‐4‐methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo

British journal of pharmacology, 1996-11, Vol.119 (6), p.1101-1108

1996

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The application of genetics to the discovery of better medicines

Pharmacogenomics, 2002-03, Vol.3 (2), p.257-263

2002

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Inhibition of leukotriene B4-receptor interaction suppresses eosinophil infiltration and disease pathology in a murine model of experimental allergic encephalomyelitis

The Journal of experimental medicine, 1996-04, Vol.183 (4), p.1893-1898

1996

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The preclinical pharmacological profile of the potent and selective leukotriene B4 antagonist CP-195543

The Journal of pharmacology and experimental therapeutics, 1998-06, Vol.285 (3), p.946

1998

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Heightened response of eosinophilic asthmatic patients to the CRTH 2 antagonist OC 000459

Allergy (Copenhagen), 2014-09, Vol.69 (9), p.1223-1232

2014

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The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696

The Journal of pharmacology and experimental therapeutics, 1995-04, Vol.273 (1), p.176

1995

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CRTH2 mediates the activation of human Th2 cells in response to PGD 2 released from IgE/anti‐IgE treated nasal polyp tissue

Allergy (Copenhagen), 2010-03, Vol.65 (3), p.304-310

2010

Volltextzugriff (PDF)

Regulation of tumour necrosis factor production by adrenal hormones in vivo: insights into the antiinflammatory activity of rolipram

British journal of pharmacology, 1996-04, Vol.117 (7), p.1530-1534

1996

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The roles of the prostaglandin D 2 receptors DP 1 and CRTH2 in promoting allergic responses

Anti‐eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459

A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses

Interaction between prostaglandin D₂ and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells

CRTH2 mediates the activation of human Th2 cells in response to PGD(2) released from IgE/anti-IgE treated nasal polyp tissue

CRTH2 mediates the activation of human Th2 cells in response to PGD₂ released from IgE/anti-IgE treated nasal polyp tissue

Systemic administration of the chemokine macrophage inflammatory protein 1α exacerbates inflammatory bowel disease in a mouse model

Interleukin 1 Induces Leukocyte Infiltration and Cartilage Proteoglycan Degradation in the Synovial Joint

The roles of the prostaglandin D sub(2) receptors DP sub(1) and CRTH2 in promoting allergic responses

The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses

The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses: Life Sciences Supplement: A selection of review articles from the 2007 Life Sciences meeting in Glasgow

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis

Striking Effect of Hydroxamic Acid Substitution on the Phosphodiesterase Type 4 (PDE4) and TNFα Inhibitory Activity of Two Series of Rolipram Analogues: Implications for a New Active Site Model of PDE4

Arthritogenic actions of recombinant IL-1 and tumour necrosis factor α in the rabbit: evidence for synergistic interactions between cytokines in vivo

2‐Amino‐4‐methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo

The application of genetics to the discovery of better medicines

Inhibition of leukotriene B4-receptor interaction suppresses eosinophil infiltration and disease pathology in a murine model of experimental allergic encephalomyelitis

The preclinical pharmacological profile of the potent and selective leukotriene B4 antagonist CP-195543

Heightened response of eosinophilic asthmatic patients to the CRTH 2 antagonist OC 000459

The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696

CRTH2 mediates the activation of human Th2 cells in response to PGD 2 released from IgE/anti‐IgE treated nasal polyp tissue

Regulation of tumour necrosis factor production by adrenal hormones in vivo: insights into the antiinflammatory activity of rolipram

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