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The Impact of Early-Phase Trial Design in the Drug Development Process

Clinical cancer research, 2019-01, Vol.25 (2), p.819-827

2019

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A web tool for designing and conducting phase I trials using the continual reassessment method

BMC cancer, 2018-02, Vol.18 (1), p.133-133, Article 133

2018

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Results of an early safety analysis of a study of the combination of pembrolizumab and pelvic chemoradiation in locally advanced cervical cancer

Cancer, 2020-11, Vol.126 (22), p.4948-4956

2020

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Implementation of adaptive methods in early‐phase clinical trials

Statistics in medicine, 2017-01, Vol.36 (2), p.215-224

2017

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Phase II randomized study of preoperative calcitriol to prevent hypocalcemia following thyroidectomy

Head & neck, 2021-10, Vol.43 (10), p.2935-2945

2021

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The Role of Early-Phase Design-Response

Clinical cancer research, 2019-05, Vol.25 (10), p.3191-3191

2019

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A Phase II Study of Dovitinib in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma

Clinical cancer research, 2017-08, Vol.23 (15), p.4138-4145

2017

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Randomized Multicenter Trial of the Effects of Melanoma-Associated Helper Peptides and Cyclophosphamide on the Immunogenicity of a Multipeptide Melanoma Vaccine

Journal of clinical oncology, 2011-07, Vol.29 (21), p.2924-2932

2011

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A multipeptide vaccine plus toll-like receptor agonists LPS or polyICLC in combination with incomplete Freund's adjuvant in melanoma patients

Journal for immunotherapy of cancer, 2019-06, Vol.7 (1), p.163-13, Article 163

2019

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Infrared thermography of cutaneous melanoma metastases

The Journal of surgical research, 2013-06, Vol.182 (1), p.e9-e14

2013

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Novel Form of Breast Intraoperative Radiation Therapy with CT-Guided High-Dose-Rate Brachytherapy: Interim Results of a Prospective Phase-II Clinical Trial

Journal of the American College of Surgeons, 2024-01, Vol.238 (1), p.10-20

2024

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Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a Multicenter Randomized Trial

Clinical cancer research, 2009-11, Vol.15 (22), p.7036-7044

2009

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Applications of the partial-order continual reassessment method in the early development of treatment combinations

Clinical trials (London, England), 2024-06, Vol.21 (3), p.331-339

2024

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Operating characteristics are needed to properly evaluate the scientific validity of phase I protocols

Contemporary clinical trials, 2021-09, Vol.108, p.106517-106517, Article 106517

2021

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Tailoring early-phase clinical trial design to address multiple research objectives

Cancer Immunology, Immunotherapy, 2020-01, Vol.69 (1), p.95-102

2020

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Evaluation of Preoperative and Intraoperative Mobile Gamma Camera Imaging in Sentinel Lymph Node Biopsy for Melanoma Independent of Preoperative Lymphoscintigraphy

The Journal of surgical research, 2023-05, Vol.285 (C), p.176-186

2023

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Randomized Comparison of ABVD and MOPP/ABV Hybrid for the Treatment of Advanced Hodgkin’s Disease: Report of an Intergroup Trial

Journal of clinical oncology, 2003-02, Vol.21 (4), p.607-614

2003

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Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund’s adjuvant (IFA) for resected high-risk melanoma

Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e003220

2021

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Characterization and comparison of innate and adaptive immune responses at vaccine sites in melanoma vaccine clinical trials

Cancer Immunology, Immunotherapy, 2021-08, Vol.70 (8), p.2151-2164

2021

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Video-Assisted Informed Consent in a Clinical Trial of Resuscitation of Extremely Preterm Infants: Lessons Learned

American journal of perinatology, 2024-05, Vol.41 (S 01), p.e187-e192

2024

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A Novel Form of Breast Intraoperative Radiation Therapy With CT-Guided High-Dose-Rate Brachytherapy: Results of a Prospective Phase 1 Clinical Trial

International journal of radiation oncology, biology, physics, 2016-09, Vol.96 (1), p.46-54

2016

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Alirocumab and plaque volume, calf muscle blood flow, and walking performance in peripheral artery disease: A randomized clinical trial

Vascular medicine (London, England), 2023-08, Vol.28 (4), p.282-289

2023

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Immunologic and Clinical Outcomes of a Randomized Phase II Trial of Two Multipeptide Vaccines for Melanoma in the Adjuvant Setting

Clinical cancer research, 2007-11, Vol.13 (21), p.6386-6395

2007

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Implementation of a Model-Based Design in a Phase Ib Study of Combined Targeted Agents

Clinical cancer research, 2017-12, Vol.23 (23), p.7158-7164

2017

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Achieving Sufficient Accrual to Address the Primary Endpoint in Phase III Clinical Trials from U.S. Cooperative Oncology Groups

Clinical cancer research, 2012-01, Vol.18 (1), p.256-262

2012

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The Impact of Early-Phase Trial Design in the Drug Development Process

A web tool for designing and conducting phase I trials using the continual reassessment method

Results of an early safety analysis of a study of the combination of pembrolizumab and pelvic chemoradiation in locally advanced cervical cancer

Implementation of adaptive methods in early‐phase clinical trials

Phase II randomized study of preoperative calcitriol to prevent hypocalcemia following thyroidectomy

The Role of Early-Phase Design-Response

A Phase II Study of Dovitinib in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma

Randomized Multicenter Trial of the Effects of Melanoma-Associated Helper Peptides and Cyclophosphamide on the Immunogenicity of a Multipeptide Melanoma Vaccine

A multipeptide vaccine plus toll-like receptor agonists LPS or polyICLC in combination with incomplete Freund's adjuvant in melanoma patients

Infrared thermography of cutaneous melanoma metastases

Novel Form of Breast Intraoperative Radiation Therapy with CT-Guided High-Dose-Rate Brachytherapy: Interim Results of a Prospective Phase-II Clinical Trial

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a Multicenter Randomized Trial

Applications of the partial-order continual reassessment method in the early development of treatment combinations

Operating characteristics are needed to properly evaluate the scientific validity of phase I protocols

Tailoring early-phase clinical trial design to address multiple research objectives

Evaluation of Preoperative and Intraoperative Mobile Gamma Camera Imaging in Sentinel Lymph Node Biopsy for Melanoma Independent of Preoperative Lymphoscintigraphy

Randomized Comparison of ABVD and MOPP/ABV Hybrid for the Treatment of Advanced Hodgkin’s Disease: Report of an Intergroup Trial

Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund’s adjuvant (IFA) for resected high-risk melanoma

Characterization and comparison of innate and adaptive immune responses at vaccine sites in melanoma vaccine clinical trials

Video-Assisted Informed Consent in a Clinical Trial of Resuscitation of Extremely Preterm Infants: Lessons Learned

A Novel Form of Breast Intraoperative Radiation Therapy With CT-Guided High-Dose-Rate Brachytherapy: Results of a Prospective Phase 1 Clinical Trial

Alirocumab and plaque volume, calf muscle blood flow, and walking performance in peripheral artery disease: A randomized clinical trial

Immunologic and Clinical Outcomes of a Randomized Phase II Trial of Two Multipeptide Vaccines for Melanoma in the Adjuvant Setting

Implementation of a Model-Based Design in a Phase Ib Study of Combined Targeted Agents

Achieving Sufficient Accrual to Address the Primary Endpoint in Phase III Clinical Trials from U.S. Cooperative Oncology Groups

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