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The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes

eLife, 2022-10, Vol.11

2022

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Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway

PLoS genetics, 2012-07, Vol.8 (7), p.e1002772-e1002772

2012

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The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

PLoS biology, 2004-08, Vol.2 (8), p.E240-E240

2004

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The Rad50 hook domain regulates DNA damage signaling and tumorigenesis

Genes & development, 2014-03, Vol.28 (5), p.451-462

2014

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Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells

PLoS genetics, 2012-08, Vol.8 (8), p.e1002935-e1002935

2012

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Functions of the MRE11 complex in the development and maintenance of oocytes

Chromosoma, 2016-03, Vol.125 (1), p.151-162

2016

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The Mre11 complex and ATM: collaborating to navigate S phase

Current Opinion in Cell Biology, 2000-06, Vol.12 (3), p.293-296

Petrini, John HJ

2000

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The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

Nature genetics, 2002-03, Vol.30 (3), p.290-294

2002

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The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex

Nature, 2007-05, Vol.447 (7141), p.218-221

2007

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Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS

Genes & development, 2009-01, Vol.23 (2), p.171-180

2009

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An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

Nature genetics, 2001-04, Vol.27 (4), p.417-421

2001

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Srs2 and Sgs1 DNA Helicases Associate with Mre11 in Different Subcomplexes following Checkpoint Activation and CDK1-Mediated Srs2 Phosphorylation

Molecular and Cellular Biology, 2005-07, Vol.25 (13), p.5738-5751

2005

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Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (8), p.2797-2802

2007

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A Touching Response to Damage

Science (American Association for the Advancement of Science), 2007-05, Vol.316 (5828), p.1138-1139

Petrini, John H. J.

2007

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Rad50S alleles of the Mre11 complex: Questions answered and questions raised

Experimental cell research, 2006-08, Vol.312 (14), p.2694-2699

2006

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Artemis and Nonhomologous End Joining-Independent Influence of DNA-Dependent Protein Kinase Catalytic Subunit on Chromosome Stability

Molecular and Cellular Biology, 2009-01, Vol.29 (2), p.503-514

2009

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NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication

DNA repair, 2009-12, Vol.8 (12), p.1363-1370

2009

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ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over: e1000042

PLoS genetics, 2008-03, Vol.4 (3)

2008

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Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates

Molecular cell, 2009-04, Vol.34 (1), p.13-25

2009

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Modeling disease in the mouse: Lessons from DNA damage response and cell cycle control genes

Journal of cellular biochemistry, 2006-02, Vol.97 (3), p.459-473

2006

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The Rad50 super(S) allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor

Genes & development, 2005-12, Vol.19 (24), p.3043-3054

2005

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Palliative bipolar electrocoagulation therapy of obstructing esophageal cancer

Gastrointestinal endoscopy, 1987-10, Vol.33 (5), p.349-353

1987

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The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis

Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells

Functions of the MRE11 complex in the development and maintenance of oocytes

The Mre11 complex and ATM: collaborating to navigate S phase

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex

Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

Srs2 and Sgs1 DNA Helicases Associate with Mre11 in Different Subcomplexes following Checkpoint Activation and CDK1-Mediated Srs2 Phosphorylation

Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53

A Touching Response to Damage

Rad50S alleles of the Mre11 complex: Questions answered and questions raised

Artemis and Nonhomologous End Joining-Independent Influence of DNA-Dependent Protein Kinase Catalytic Subunit on Chromosome Stability

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication

ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over: e1000042

A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome: e1003695

Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates

Modeling disease in the mouse: Lessons from DNA damage response and cell cycle control genes

The Rad50 super(S) allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor

Palliative bipolar electrocoagulation therapy of obstructing esophageal cancer

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