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Synthesis, radiolabeling with fluorine-18 and preliminary in vivo evaluation of a heparan sulphate mimetic as potent angiogenesis and heparanase inhibitor for cancer applications

Organic & biomolecular chemistry, 2016-01, Vol.14 (6), p.1915-1920

2016

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Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Journal of thrombosis and haemostasis, 2008-10, Vol.6 (10), p.1697-1706

2008

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First in man study of EP217609, a new long-acting, neutralisable parenteral antithrombotic with a dual mechanism of action

European journal of clinical pharmacology, 2016-09, Vol.72 (9), p.1041-1050

2016

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Neutralization of EP217609, a new dual-action FIIa/FXa anticoagulant, by its specific antidote avidin: a phase I study

European journal of clinical pharmacology, 2017, Vol.73 (1), p.15-28

2017

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Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Journal of thrombosis and haemostasis, 2008-10, Vol.6 (10), p.1697-1706

2008

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Conformation of heparin pentasaccharide bound to antithrombin III

Biochemical journal, 2001-10, Vol.359 (Pt 2), p.265-272

2001

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EP42675, a synthetic parenteral dual‐action anticoagulant: pharmacokinetics, pharmacodynamics, and absence of interactions with antiplatelet drugs

Journal of thrombosis and haemostasis, 2014-01, Vol.12 (1), p.24-33

2014

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Biochemical and Pharmacological Properties of SANORG 34006, a Potent and Long-Acting Synthetic Pentasaccharide

Blood, 1998-06, Vol.91 (11), p.4197-4205

1998

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A Synthetic Antithrombin III Binding Pentasaccharide Is Now a Drug! What Comes Next?

Angewandte Chemie International Edition, 2004-06, Vol.43 (24), p.3118-3133

2004

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SR123781A, a synthetic heparin mimetic

Thrombosis and haemostasis, 2001-05, Vol.85 (5), p.852-860

2001

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1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site

Biochimie, 2003-01, Vol.85 (1-2), p.83-89

2003

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1976–1983, a critical period in the history of heparin: the discoveryof the antithrombin binding site

Biochimie, 2003-02, Vol.85 (1), p.83-89

2003

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Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans

Trends in Biochemical Sciences, 1988-06, Vol.13 (6), p.221-225

1988

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The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity

Nature structural & molecular biology, 2004-09, Vol.11 (9), p.863-867

2004

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Pharmacokinetics of new synthetic heparin mimetics

Thrombosis and haemostasis, 2002-06, Vol.87 (6), p.985-989

2002

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Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin

Blood, 2005-01, Vol.105 (1), p.139-144

2005

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Molecular model of human heparanase with proposed binding mode of a heparan sulfate oligosaccharide and catalytic amino acids

Biopolymers, 2012-01, Vol.97 (1), p.21-34

2012

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The Anticoagulant Activation of Antithrombin by Heparin

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (26), p.14683-14688

1997

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Inhibition of coagulation proteases Xa and IIa decreases ischemia-reperfusion injuries in a preclinical renal transplantation model

Translational research : the journal of laboratory and clinical medicine, 2016-12, Vol.178, p.95-106.e1

2016

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Experimental Proof for the Structure of a Thrombin-Inhibiting Heparin Molecule

Chemistry : a European journal, 2001-02, Vol.7 (4), p.858-873

2001

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Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

Journal of thrombosis and haemostasis, 2003-09, Vol.1 (9), p.2008-2013

2003

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Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

Thrombosis and haemostasis, 2004-11, Vol.92 (5), p.929-939

2004

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The structure of synthetic oligosaccharides in relation to factor IXa inhibition

Thrombosis and haemostasis, 2002-09, Vol.88 (3), p.432-435

2002

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Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells

Haematologica (Roma), 2012-04, Vol.97 (4), p.491-499

2012

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Large, Tissue-regulated Domain Diversity of Heparan Sulfates Demonstrated by Phage Display Antibodies

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.10982-10986

2002

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Synthesis, radiolabeling with fluorine-18 and preliminary in vivo evaluation of a heparan sulphate mimetic as potent angiogenesis and heparanase inhibitor for cancer applications

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

First in man study of EP217609, a new long-acting, neutralisable parenteral antithrombotic with a dual mechanism of action

Neutralization of EP217609, a new dual-action FIIa/FXa anticoagulant, by its specific antidote avidin: a phase I study

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Conformation of heparin pentasaccharide bound to antithrombin III

EP42675, a synthetic parenteral dual‐action anticoagulant: pharmacokinetics, pharmacodynamics, and absence of interactions with antiplatelet drugs

Biochemical and Pharmacological Properties of SANORG 34006, a Potent and Long-Acting Synthetic Pentasaccharide

A Synthetic Antithrombin III Binding Pentasaccharide Is Now a Drug! What Comes Next?

SR123781A, a synthetic heparin mimetic

1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site

1976–1983, a critical period in the history of heparin: the discoveryof the antithrombin binding site

Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans

The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity

Pharmacokinetics of new synthetic heparin mimetics

Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin

Molecular model of human heparanase with proposed binding mode of a heparan sulfate oligosaccharide and catalytic amino acids

The Anticoagulant Activation of Antithrombin by Heparin

Inhibition of coagulation proteases Xa and IIa decreases ischemia-reperfusion injuries in a preclinical renal transplantation model

Experimental Proof for the Structure of a Thrombin-Inhibiting Heparin Molecule

Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

The structure of synthetic oligosaccharides in relation to factor IXa inhibition

Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells

Large, Tissue-regulated Domain Diversity of Heparan Sulfates Demonstrated by Phage Display Antibodies

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