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In Vitro Activity of Tigecycline against Isolates from Patients Enrolled in Phase 3 Clinical Trials of Treatment for Complicated Skin and Skin-Structure Infections and Complicated Intra-Abdominal Infections

Clinical infectious diseases, 2005-09, Vol.41 (Supplement-5), p.S315-S332

2005

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Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

Antimicrobial Agents and Chemotherapy, 2005-09, Vol.49 (9), p.3903-3909

2005

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Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors

Journal of the American Chemical Society, 2002-09, Vol.124 (35), p.10260-10261

2002

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In Vitro and In Vivo Activities of Tigecycline (GAR-936), Daptomycin, and Comparative Antimicrobial Agents against Glycopeptide-Intermediate Staphylococcus aureus and Other Resistant Gram-Positive Pathogens

Antimicrobial Agents and Chemotherapy, 2002-08, Vol.46 (8), p.2595-2601

2002

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Occurrence of Tetracycline Resistance Genes among Escherichia coli Isolates from the Phase 3 Clinical Trials for Tigecycline

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3205-3211

2007

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Effect of Medium Age and Supplementation with the Biocatalytic Oxygen-Reducing Reagent Oxyrase on In Vitro Activities of Tigecycline against Recent Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2005-09, Vol.49 (9), p.3910-3918

2005

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Efficacy of Piperacillin Combined with the Penem β-Lactamase Inhibitor BLI-489 in Murine Models of Systemic Infection

Antimicrobial Agents and Chemotherapy, 2009-04, Vol.53 (4), p.1698-1700

2009

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Comparative In Vitro Activities of AC98-6446, a Novel Semisynthetic Glycopeptide Derivative of the Natural Product Mannopeptimycin α, and Other Antimicrobial Agents against Gram-Positive Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2004-03, Vol.48 (3), p.739-746

2004

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3,5-Dioxopyrazolidines, Novel Inhibitors of UDP-N- Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria

Antimicrobial Agents and Chemotherapy, 2006-02, Vol.50 (2), p.556-564

2006

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In Vitro Activity of Tigecycline against Staphylococcus epidermidis Growing in an Adherent-Cell Biofilm Model

Antimicrobial Agents and Chemotherapy, 2003-12, Vol.47 (12), p.3967-3969

2003

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Validation and Reproducibility Assessment of Tigecycline MIC Determinations by Etest

Journal of Clinical Microbiology, 2007-08, Vol.45 (8), p.2474-2479

2007

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Establishment of In Vitro Susceptibility Testing Methodologies and Comparative Activities of Piperacillin in Combination with the Penem β-Lactamase Inhibitor BLI-489

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.370-384

2009

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Naphthyl Tetronic Acids as Multi-Target Inhibitors of Bacterial Peptidoglycan Biosynthesis

ChemMedChem, 2007-10, Vol.2 (10), p.1414-1417

2007

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In vitro antibacterial activities of tigecycline in combination with other antimicrobial agents determined by chequerboard and time-kill kinetic analysis

Journal of antimicrobial chemotherapy, 2006-03, Vol.57 (3), p.573-576

2006

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In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4589-4596

2004

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Therapeutic Efficacy of GAR-936, a Novel Glycylcycline, in a Rat Model of Experimental Endocarditis

Antimicrobial Agents and Chemotherapy, 2000-11, Vol.44 (11), p.3022-3027

2000

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Novel α-Pyrones Produced by a Marine Pseudomonas sp. F92S91: Taxonomy and Biological Activities

The Journal of Antibiotics, 2003/12/25, Vol.56(12), pp.1033-1044

2003

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Design and synthesis of indolo[2,3- a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1427-1431

2004

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Pyrosequencing Using the Single-Nucleotide Polymorphism Protocol for Rapid Determination of TEM- and SHV-Type Extended-Spectrum β-Lactamases in Clinical Isolates and Identification of the Novel β-Lactamase Genes blaSHV-48, blaSHV-105, and blaTEM-155

Antimicrobial Agents and Chemotherapy, 2009-03, Vol.53 (3), p.977-986

2009

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Pyrazolidine-3,5-diones and 5-Hydroxy-1H-pyrazol-3(2H)-ones, Inhibitors of UDP-N-acetylenolpyruvyl Glucosamine Reductase

Journal of medicinal chemistry, 2006-10, Vol.49 (20), p.6027-6036

2006

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Synthesis and activity of novel benzoxazole derivatives of mannopeptimycin glycopeptide antibiotics

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (15), p.2607-2610

2003

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Resistance development profiling of piperacillin in combination with the novel β-lactamase inhibitor BLI-489

Journal of antimicrobial chemotherapy, 2010-02, Vol.65 (2), p.252-257

2010

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Mannopeptimycin esters and carbonates, potent antibiotic agents against drug-resistant bacteria

Bioorganic & medicinal chemistry letters, 2004-01, Vol.14 (1), p.279-282

2004

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In vitro Activity of Tigecycline Against Patient Isolates Collected during Phase 3 Clinical Trials for Hospital Acquired Pneumonia

Infectious disease reports, 2010-02, Vol.2 (1), p.e1-e1

2010

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5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (4), p.1890-1902

2008

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In Vitro Activity of Tigecycline against Isolates from Patients Enrolled in Phase 3 Clinical Trials of Treatment for Complicated Skin and Skin-Structure Infections and Complicated Intra-Abdominal Infections

Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors

In Vitro and In Vivo Activities of Tigecycline (GAR-936), Daptomycin, and Comparative Antimicrobial Agents against Glycopeptide-Intermediate Staphylococcus aureus and Other Resistant Gram-Positive Pathogens

Occurrence of Tetracycline Resistance Genes among Escherichia coli Isolates from the Phase 3 Clinical Trials for Tigecycline

Effect of Medium Age and Supplementation with the Biocatalytic Oxygen-Reducing Reagent Oxyrase on In Vitro Activities of Tigecycline against Recent Clinical Isolates

Efficacy of Piperacillin Combined with the Penem β-Lactamase Inhibitor BLI-489 in Murine Models of Systemic Infection

Comparative In Vitro Activities of AC98-6446, a Novel Semisynthetic Glycopeptide Derivative of the Natural Product Mannopeptimycin α, and Other Antimicrobial Agents against Gram-Positive Clinical Isolates

3,5-Dioxopyrazolidines, Novel Inhibitors of UDP-N- Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria

In Vitro Activity of Tigecycline against Staphylococcus epidermidis Growing in an Adherent-Cell Biofilm Model

Validation and Reproducibility Assessment of Tigecycline MIC Determinations by Etest

Establishment of In Vitro Susceptibility Testing Methodologies and Comparative Activities of Piperacillin in Combination with the Penem β-Lactamase Inhibitor BLI-489

Naphthyl Tetronic Acids as Multi-Target Inhibitors of Bacterial Peptidoglycan Biosynthesis

In vitro antibacterial activities of tigecycline in combination with other antimicrobial agents determined by chequerboard and time-kill kinetic analysis

In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

Therapeutic Efficacy of GAR-936, a Novel Glycylcycline, in a Rat Model of Experimental Endocarditis

Novel α-Pyrones Produced by a Marine Pseudomonas sp. F92S91: Taxonomy and Biological Activities

Design and synthesis of indolo[2,3- a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction

Pyrosequencing Using the Single-Nucleotide Polymorphism Protocol for Rapid Determination of TEM- and SHV-Type Extended-Spectrum β-Lactamases in Clinical Isolates and Identification of the Novel β-Lactamase Genes blaSHV-48, blaSHV-105, and blaTEM-155

Pyrazolidine-3,5-diones and 5-Hydroxy-1H-pyrazol-3(2H)-ones, Inhibitors of UDP-N-acetylenolpyruvyl Glucosamine Reductase

Synthesis and activity of novel benzoxazole derivatives of mannopeptimycin glycopeptide antibiotics

Resistance development profiling of piperacillin in combination with the novel β-lactamase inhibitor BLI-489

Mannopeptimycin esters and carbonates, potent antibiotic agents against drug-resistant bacteria

In vitro Activity of Tigecycline Against Patient Isolates Collected during Phase 3 Clinical Trials for Hospital Acquired Pneumonia

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

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