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Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

Acta neuropathologica, 2016-05, Vol.131 (5), p.753-773

2016

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Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (6), p.1298-1303

2018

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Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature

The Journal of clinical investigation, 2014-10, Vol.124 (10), p.4564-4576

2014

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Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19

JCI insight, 2021-10, Vol.6 (20)

2021

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VE-PTP inhibition elicits eNOS phosphorylation to blunt endothelial dysfunction and hypertension in diabetes

Cardiovascular research, 2021-05, Vol.117 (6), p.1546-1556

2021

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Targeting Tie2 for Treatment of Diabetic Retinopathy and Diabetic Macular Edema

Current Diabetes Reports, 2016-12, Vol.16 (12), p.126-126, Article 126

2016

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Controversial roles for dexamethasone in glioblastoma – Opportunities for novel vascular targeting therapies

Journal of cerebral blood flow and metabolism, 2019-08, Vol.39 (8), p.1460-1468

2019

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Preclinical models of human peripheral arterial occlusive disease: implications for investigation of therapeutic agents

Journal of applied physiology (1985), 2004-08, Vol.97 (2), p.773-780

2004

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Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

Circulation research, 1997-10, Vol.81 (4), p.567-574

1997

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A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

Investigative ophthalmology & visual science, 2020-12, Vol.61 (14), p.12

2020

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Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO 4) as the active component

Journal of inorganic biochemistry, 2003-08, Vol.96 (2), p.321-330

2003

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Vascular Endothelial Growth Factor Receptor Expression During Embryogenesis and Tissue Repair Suggests a Role in Endothelial Differentiation and Blood Vessel Growth

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.8915-8919

1993

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The Endothelial Receptor Tyrosine Kinase Tie1 Activates Phosphatidylinositol 3-Kinase and Akt To Inhibit Apoptosis

Molecular and Cellular Biology, 2002-03, Vol.22 (6), p.1704-1713

2002

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Tie2 Activation via VE-PTP Inhibition With Razuprotafib as an Adjunct to Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Translational vision science & technology, 2022-01, Vol.11 (1), p.7-7

2022

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Tyrosine phosphatase inhibition augments collateral blood flow in a rat model of peripheral vascular disease

American journal of physiology. Heart and circulatory physiology, 2004-07, Vol.287 (1), p.H268-H276

2004

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Induction and maintenance of increased VEGF protein by chronic motor nerve stimulation in skeletal muscle

American journal of physiology. Heart and circulatory physiology, 1998-03, Vol.274 (3), p.H860-H867

1998

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Tyrosine phosphatases in vessel wall signaling

Cardiovascular research, 2005-02, Vol.65 (3), p.587-598

2005

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Antiangiogenic Gene Therapy Targeting the Endothelium-Specific Receptor Tyrosine Kinase Tie2

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (15), p.8829-8834

1998

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1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1574-1578

2006

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Vascular Endothelial Growth Factor and the Angiopoietins: Working Together to Build a Better Blood Vessel

Circulation research, 1998-08, Vol.83 (3), p.342-343

Peters, Kevin G

1998

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Fetal Liver Kinase 1 is a Receptor for Vascular Endothelial Growth Factor and is Selectively Expressed in Vascular Endothelium

Proceedings of the National Academy of Sciences - PNAS, 1993-08, Vol.90 (16), p.7533-7537

1993

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Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency : Support for an endothelium-dependent mechanism

Cardiovascular research, 2006-03, Vol.69 (4), p.925-935

2006

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Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.4131-4140

1998

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A Nonspecific Phosphotyrosine Phosphatase Inhibitor, Bis(maltolato)oxovanadium(IV), Improves Glucose Tolerance and Prevents Diabetes in Zucker Diabetic Fatty Rats

Experimental biology and medicine (Maywood, N.J.), 2005-03, Vol.230 (3), p.207-216

2005

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Large Induction of Keratinocyte Growth Factor Expression in the Dermis During Wound Healing

Proceedings of the National Academy of Sciences - PNAS, 1992-08, Vol.89 (15), p.6896-6900

1992

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Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP

Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature

Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19

VE-PTP inhibition elicits eNOS phosphorylation to blunt endothelial dysfunction and hypertension in diabetes

Targeting Tie2 for Treatment of Diabetic Retinopathy and Diabetic Macular Edema

Controversial roles for dexamethasone in glioblastoma – Opportunities for novel vascular targeting therapies

Preclinical models of human peripheral arterial occlusive disease: implications for investigation of therapeutic agents

Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO 4) as the active component

Vascular Endothelial Growth Factor Receptor Expression During Embryogenesis and Tissue Repair Suggests a Role in Endothelial Differentiation and Blood Vessel Growth

The Endothelial Receptor Tyrosine Kinase Tie1 Activates Phosphatidylinositol 3-Kinase and Akt To Inhibit Apoptosis

Tie2 Activation via VE-PTP Inhibition With Razuprotafib as an Adjunct to Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Tyrosine phosphatase inhibition augments collateral blood flow in a rat model of peripheral vascular disease

Induction and maintenance of increased VEGF protein by chronic motor nerve stimulation in skeletal muscle

Tyrosine phosphatases in vessel wall signaling

Antiangiogenic Gene Therapy Targeting the Endothelium-Specific Receptor Tyrosine Kinase Tie2

1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Vascular Endothelial Growth Factor and the Angiopoietins: Working Together to Build a Better Blood Vessel

Fetal Liver Kinase 1 is a Receptor for Vascular Endothelial Growth Factor and is Selectively Expressed in Vascular Endothelium

Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency : Support for an endothelium-dependent mechanism

Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt

A Nonspecific Phosphotyrosine Phosphatase Inhibitor, Bis(maltolato)oxovanadium(IV), Improves Glucose Tolerance and Prevents Diabetes in Zucker Diabetic Fatty Rats

Large Induction of Keratinocyte Growth Factor Expression in the Dermis During Wound Healing

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